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How to get fromMedford to St. Louisby plane, bus (Greyhound, Flixbus), bus, train, or car

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There are 5 ways to get from Medford to St. Louis by plane, bus (Greyhound, Flixbus), bus, train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly

    best
    1. Fly from Rogue Valley International - Medford Airport (MFR) to Lambert–St. Louis International Airport (STL)plane plane MFR - STL
    6h 23m
    $153–615

  2. Bus

    1. Take the bus from Medford to JCT Transit Hub - 300 NW 5th St - Rt 100bus bus 100
    2. Take the bus from Grants Pass to Portland Curbside Bus Stopbus bus
    3. Take the bus from Portland Curbside Bus Stop to Pasco Bus Stopbus bus
    4. Take the bus from Pasco Bus Stop to Denver Union Stationbus bus
    5. Take the bus from Denver Union Station to St Louis Bus Stationbus bus
    2d 4h
    $366–727

  3. Bus, train

    1. Take the bus from Medford to JCT Transit Hub - 300 NW 5th St - Rt 100bus bus 100
    2. Take the bus from Grants Pass to Portland Curbside Bus Stopbus bus
    3. Take the train from Portland to Chicago Union Stationtrain train
    4. Take the train from Chicago Union Station to St. Louistrain train
    2d 11h
    $826–1,767

  4. Drive 2,037 mi

    1. Drive from Medford to St. Louiscar car 2,037 mi
    34h 14m
    $372–537

  5. Bus, train via Los Angeles

    1. Take the bus from Front Street Station - Medford to Klamath Falls Amtrak Stationbus bus
    2. Take the train from Klamath Falls to Los Angelestrain train
    3. Take the train from Los Angeles to St. Louistrain train
    3d 11h
    $1,046–2,243

Medford to St. Louis by bus and foot

Calendar7Weekly Services
Duration2d 4hAverage Duration
Ticket$366Cheapest Price
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Questions & Answers

Map of how to get from Medford to St. Louis.ExpandLaunch map view
  • Distance: 1,728.1 mi
  • Duration: 6h 23m

What companies run services between Medford, OR, USA and St. Louis, MO, USA?

United Airlines, Alaska Airlines, Inc., and Delta fly from Rogue Valley International - Medford Airport (MFR) to Lambert–St. Louis International Airport (STL) 5 times a day. Alternatively, you can take a bus from Medford to St Louis Bus Station via JCT Transit Hub - 300 NW 5th St - Rt 100, Grants Pass, Portland Curbside Bus Stop, Pasco Bus Stop, and Denver Union Station in around 2d 4h.

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