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How to get fromMedford to Winston-Salemby plane, bus, train, bus (Greyhound, Flixbus), or car

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There are 7 ways to get from Medford to Winston-Salem by plane, bus, train, bus (Greyhound, Flixbus), or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Piedmont Triad International Airport

    best
    1. Fly from Rogue Valley International - Medford Airport (MFR) to Piedmont Triad International Airport (GSO)plane plane MFR - GSO
    10h 51m
    $243–881

  2. Fly to Raleigh-Durham International Airport, bus

    cheapest
    1. Fly from Rogue Valley International - Medford Airport (MFR) to Raleigh-Durham International Airport (RDU)plane plane MFR - RDU
    2. Take the bus from Durham to Winston Salem(Trans Center)bus bus
    11h 22m
    $177–640

  3. Bus, train via Columbus

    1. Take the bus from Front Street Station - Medford to Newman United Methodist Church - Grants Passbus bus
    2. Take the bus from Grants Pass to Portland Curbside Bus Stopbus bus
    3. Take the train from Portland to Chicago Union Stationtrain train
    4. Take the bus from Chicago to Columbus - Mound Stbus bus
    5. Take the bus from Columbus to Winston Salem(Trans Center)bus bus
    3d 1h
    $833–1,812

  4. Bus

    1. Take the bus from Medford to JCT Transit Hub - 300 NW 5th St - Rt 100bus bus
    2. Take the bus from Grants Pass to Seattle Bus Stationbus bus
    3. Take the bus from Seattle Bus Station to Denver Union Stationbus bus
    4. Take the bus from Denver Union Station to St Louis Bus Stationbus bus
    5. Take the bus from St Louis Bus Station to Atlanta Bus Stationbus bus
    6. Take the bus from Atlanta Bus Station to Winston Salem(Trans Center)bus bus
    3d 5h
    $506–1,017

  5. Drive 2,715 mi

    1. Drive from Medford to Winston-Salemcar car 2,715 mi
    46h 33m
    $496–716

  6. Fly to Charlotte Douglas International Airport, bus

    1. Fly from Rogue Valley International - Medford Airport (MFR) to Charlotte Douglas International Airport (CLT)plane plane MFR - CLT
    2. Take the bus from Charlotte Bus Station to Winston Salem(Trans Center)bus bus
    10h 29m
    $210–813

  7. Bus, train

    1. Take the bus from Medford to JCT Transit Hub - 300 NW 5th St - Rt 100bus bus
    2. Take the bus from Grants Pass to Portland Curbside Bus Stopbus bus
    3. Take the train from Portland to Chicago Union Stationtrain train
    4. Take the train from Chicago Union Station to Raleigh Union Stationtrain train
    5. Take the train from Raleigh Union Station to Greensborotrain train
    6. Take the bus from Greensboro Bus Stop to Winston Salem(Trans Center)bus bus
    3d 10h
    $1,095–2,335

Medford to Winston-Salem by bus, train, and foot

Calendar7Weekly Services
Duration3d 1hAverage Duration
Ticket$833Cheapest Price
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Questions & Answers

Map of how to get from Medford to Winston-Salem.ExpandLaunch map view
  • Distance: 2,336.1 mi
  • Duration: 10h 51m

What companies run services between Medford, OR, USA and Winston-Salem, NC, USA?

Delta, United Airlines, and three other airlines fly from Rogue Valley International - Medford Airport (MFR) to Piedmont Triad International Airport (GSO) 5 times a day. Alternatively, you can take a bus from Medford to Winston Salem(Trans Center) via JCT Transit Hub - 300 NW 5th St - Rt 100, Grants Pass, Seattle Bus Station, Denver Union Station, St Louis Bus Station, and Atlanta Bus Station in around 3d 5h.

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