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How to get fromMedina to Indianapolisby bus (Greyhound, Flixbus), car, plane, bus (Greyhound), or bus (Flixbus)

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There are 6 ways to get from Medina to Indianapolis by bus (Greyhound, Flixbus), car, plane, bus (Greyhound), or bus (Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus

    best
    1. Take the bus from West Salem Bus Station to Columbus - Downtown - Mound Stbus bus Cleveland
    2. Take the bus from Columbus to Indianapolisbus bus FlixBus 2511 / ...
    6h 34m
    $104–152

  2. Drive 281.2 mi

    cheapest
    1. Drive from Medina to Indianapoliscar car 281.2 mi
    4h 54m
    $52–75

  3. Fly

    1. Fly from Cleveland-Hopkins International Airport (CLE) to Indianapolis (IND)plane plane CLE - IND
    4h 47m
    $152–628

  4. Bus via Indianapolis Union Station

    1. Take the bus from West Salem Bus Station to Columbus - Downtown - Mound Stbus bus Cleveland
    2. Take the bus from Columbus to Indianapolis Union Stationbus bus Greyhound US0421
    7h
    $101–154

  5. Bus #2

    1. Take the bus from West Salem Bus Station to Dayton Trotwood Bus Stationbus bus Greyhound US0105
    2. Take the bus from Dayton Trotwood Bus Station to Indianapolisbus bus FlixBus 2511 / ...
    7h 45m
    $102–150

  6. Bus via Robert K Pfaff Transit Center - Akron

    1. Take the bus from Robert K Pfaff Transit Center - Akron to Columbus, Ohio Greyhound Stationbus bus 379 D
    2. Take the bus from Columbus to Indianapolisbus bus FlixBus 2511 / ...
    10h 44m
    $115–163

Cleveland-Hopkins International Airport (CLE) to Indianapolis (IND) flights

Calendar120Weekly Planes
Duration4h 28mAverage Duration
Ticket$86Cheapest Price
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Questions & Answers

Map of how to get from Medina to Indianapolis.ExpandLaunch map view
  • Distance: 292.9 mi
  • Duration: 6h 34m

What companies run services between Medina, OH, USA and Indianapolis, IN, USA?

You can take a vehicle from Medina to Indianapolis via West Salem Bus Station, Columbus - Downtown - Mound St, S Grant Ave & E Mound St, S High St & E Rich St, and Columbus in around 6h 34m. Alternatively, Delta, Southwest Airlines, and three other airlines fly from Cleveland-Hopkins International Airport (CLE) to Indianapolis (IND) hourly.

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