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How to get fromMelbourne to Des Moinesby plane, shuttle, bus, car, or train

Find Transport to Des Moines

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There are 7 ways to get from Melbourne to Des Moines by plane, shuttle, bus, car, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Melbourne International Airport

    best
    1. Fly from Melbourne International Airport (MLB) to Des Moines (DSM)plane plane MLB - DSM
    6h 28m
    $198–872

  2. Shuttle, bus

    1. Take a shuttle bus from Melbourne, FL - Mobil Gas to Orlando Airportshuttle bus
    2. Take the bus from Orlando to Atlanta Bus Stationbus bus
    3. Take the bus from Atlanta Bus Station to St Louis Bus Stationbus bus
    4. Take the bus from St Louis Bus Station to Des Moinesbus bus
    35h 51m
    $268–468

  3. Drive, train, bus

    1. Drive from Melbourne to Kissimmee Amtrak Stationcar car
    2. Take the train from Kissimmee Amtrak Station to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Galesburg Amtrak Stationtrain train
    4. Take the bus from Galesburg to Des Moinesbus bus
    2d 2h
    $640–1,384

  4. Drive 1,382.2 mi

    1. Drive from Melbourne to Des Moinescar car 1,382.2 mi
    24h 2m
    $253–365

  5. Drive to Daytona Beach International Airport, fly

    1. Drive from Melbourne to Daytona-Beach-Airport-DABcar car
    2. Fly from Daytona Beach International Airport (DAB) to Des Moines (DSM)plane plane DAB - DSM
    6h 30m
    $263–1,144

  6. Shuttle to Orlando, fly

    1. Take a shuttle bus from Melbourne, FL - Mobil Gas to Orlando Airportshuttle bus
    2. Fly from Orlando (MCO) to Des Moines (DSM)plane plane MCO - DSM
    8h 49m
    $234–838

  7. Drive to Orlando Sanford, fly

    1. Drive from Melbourne to Orlando-Sanford-Airport-SFBcar car
    2. Fly from Orlando Sanford (SFB) to Des Moines (DSM)plane plane SFB - DSM
    4h 43m
    $200–840

Melbourne to Des Moines by bus and shuttle

Calendar6Weekly Services
Duration35h 51mAverage Duration
Ticket$268Cheapest Price
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Questions & Answers

Map of how to get from Melbourne to Des Moines.ExpandLaunch map view
  • Distance: 1,190.6 mi
  • Duration: 6h 28m

What companies run services between Melbourne, FL, USA and Des Moines, IA, USA?

Delta and American Airlines fly from Melbourne International Airport (MLB) to Des Moines (DSM) 5 times a day.

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