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How to get fromMelbourne to Florenceby plane, car, train, shuttle, bus, or taxi

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There are 5 ways to get from Melbourne to Florence by plane, car, train, shuttle, bus, or taxi

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly

    best
    1. Fly from Melbourne International Airport (MLB) to Florence Regional Airport (FLO)plane plane MLB - FLO
    6h 41m
    $76–384

  2. Drive, train (Amtrak)

    1. Drive from Melbourne to Kissimmee Amtrak Stationcar car
    2. Take the train from Kissimmee Amtrak Station to Florence Stationtrain train Silver Meteor
    11h 31m
    $170–354

  3. Shuttle, bus

    1. Take a shuttle bus from Melbourne, FL - Mobil Gas to Orlando Airportshuttle bus Northbound
    2. Take the bus from Orlando Bus Station to Florencebus bus FlixBus N2472
    13h 45m
    $146–208

  4. Drive 480.4 mi

    1. Drive from Melbourne to Florencecar car 480.4 mi
    7h 58m
    $88–127

  5. Taxi, bus

    1. Take the taxi from Melbourne to Sebastiantaxi taxi
    2. Take the bus from Sebastian to Jacksonvillebus bus
    3. Take the bus from Jacksonville to Sumter Bus Stopbus bus
    4. Take the bus from Sumter Bus Stop to Florence Bus Stationbus bus
    14h 14m
    $166–264

Melbourne International Airport (MLB) to Florence Regional Airport (FLO) flights

Calendar15Weekly Planes
Duration8h 18mAverage Duration
Ticket$67Cheapest Price
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Questions & Answers

Map of how to get from Melbourne to Florence.ExpandLaunch map view
  • Distance: 427.7 mi
  • Duration: 6h 41m

What companies run services between Melbourne, FL, USA and Florence, SC, USA?

American Airlines flies from Melbourne International Airport (MLB) to Florence Regional Airport (FLO) twice daily.

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