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How to get fromMelbourne to Key West (Island)by bus, shuttle, plane, taxi, car, or train

Find Transport to Key West (Island)

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There are 8 ways to get from Melbourne to Key West (Island) by bus, shuttle, plane, taxi, car, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Line 20 bus, shuttle to Orlando, fly

    best
    1. Take the bus from Melbourne Square Mall to West New Haven Ave @ Goodwillbus bus
    2. Take a shuttle bus from Melbourne, FL - Mobil Gas to Orlando Airportshuttle bus
    3. Fly from Orlando (MCO) to Key West International Airport (EYW)plane plane MCO - EYW
    4h 53m
    $126–716

  2. Drive to Orlando Sanford, fly

    cheapest
    1. Drive from Melbourne to Orlando-Sanford-Airport-SFBcar car
    2. Fly from Orlando Sanford (SFB) to Key West International Airport (EYW)plane plane SFB - EYW
    2h 55m
    $48–269

  3. Taxi, bus via Fort Pierce South

    1. Take the taxi from Melbourne to Sebastiantaxi taxi
    2. Take the bus from Sebastian to Fort Piercebus bus
    3. Take the bus from Fort Pierce to Miami Airportbus bus
    4. Take the bus from Miami Airport Station to Key West Airportbus bus
    10h
    $143–221

  4. Drive 332 mi

    1. Drive from Melbourne to Key Westcar car 332 mi
    6h 25m
    $61–88

  5. Fly from Melbourne International Airport

    1. Fly from Melbourne International Airport (MLB) to Key West International Airport (EYW)plane plane MLB - EYW
    6h 1m
    $82–392

  6. Taxi, bus, bus to Miami International Airport, fly

    1. Take the taxi from Melbourne to Sebastiantaxi taxi
    2. Take the bus from Sebastian to Fort Piercebus bus
    3. Take the bus from Fort Pierce to Miami Airportbus bus
    4. Fly from Miami International Airport (MIA) to Key West International Airport (EYW)plane plane MIA - EYW
    6h 25m
    $147–386

  7. Drive, train, bus

    1. Drive from Melbourne to Orlandocar car
    2. Take the train from Orlando to Miamitrain train
    3. Take the bus from Miami Airport Station to Key West Airportbus bus
    10h 45m
    $77–234

  8. Taxi, bus

    1. Take the taxi from Melbourne to Sebastiantaxi taxi
    2. Take the bus from Sebastian to Miami Airport Stationbus bus
    3. Take the bus from Miami Airport Station to Key West Airportbus bus
    11h 19m
    $134–197

Orlando (MCO) to Key West International Airport (EYW) flights

Calendar10Weekly Planes
Duration2h 12mAverage Duration
Ticket$37Cheapest Price
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Questions & Answers

Map of how to get from Melbourne to Key West (Island).ExpandLaunch map view
  • Distance: 345.9 mi
  • Duration: 4h 53m

What companies run services between Melbourne, FL, USA and Key West (Island), FL, USA?

Delta and American Airlines fly from Melbourne International Airport (MLB) to Key West International Airport (EYW) 4 times a day.

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