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How to get fromMelrose Park to Indianapolisby bus (Greyhound), train (Amtrak), car, bus, plane, or bus (Flixbus)

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There are 6 ways to get from Melrose Park to Indianapolis by bus (Greyhound), train (Amtrak), car, bus, plane, or bus (Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus via Kedzie-Homan (Greyhound)

    best
    1. Take the bus from Chicago Bus Station to Indianapolis Union Stationbus bus Greyhound US0100 / ...
    5h 29m
    $37–60
  2. Drive  191.8 mi

    cheapest
    1. Drive from Melrose Park to Indianapoliscar car 191.8 mi
    3h 29m
    $33–48
  3. Train (Amtrak)

    1. Take the train from Chicago Union Station to Indianapolistrain train Cardinal
    6h 30m
    $107–178
  4. Line 303 bus to Chicago O'Hare International Airport, fly

    1. Take the bus from Broadway Ave & Division St to Rosemont CTA Station - Bus Stop Fbus bus
    2. Fly from Chicago O'Hare International Airport (ORD) to Indianapolis (IND)plane plane ORD - IND
    3h 49m
    $506–860
  5. Bus (Flixbus)

    1. Take the bus from Chicago Bus Station to Indianapolisbus bus FlixBus 2511 / ...
    6h 20m
    $35–51
  6. Line 309 bus to Chicago Midway International Airport, fly

    1. Take the bus from Lake St & 19th Ave to Lake St & Austin Blvdbus bus
    2. Fly from Chicago Midway International Airport (MDW) to Indianapolis (IND)plane plane MDW - IND
    4h 31m
    $81–608

Melrose Park to Indianapolis by bus and subway (Greyhound)

Calendar70Weekly Services
Duration5h 29mAverage Duration
Ticket$37Cheapest Price
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Comparing Your Travel Options

What companies run services between Melrose Park, IL, USA and Indianapolis, IN, USA?

Greyhound USA operates a bus from Chicago Bus Station to Indianapolis Union Station every 3 hours. Tickets cost $30–50 and the journey takes 3h 5m. Alternatively, Amtrak operates a train from Chicago Union Station to Indianapolis 3 times a week. Tickets cost $100–170 and the journey takes 4h 54m.

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