There are 6 ways to get from Melrose Park to Indianapolis by bus (Greyhound), train (Amtrak), car, bus, plane, or bus (Flixbus)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus via Kedzie-Homan (Greyhound)
best- Take the bus from Chicago Bus Station to Indianapolis Union Stationbus Greyhound US0100 / ...
5h 29m$37–60Drive 191.8 mi
cheapest- Drive from Melrose Park to Indianapoliscar 191.8 mi
3h 29m$33–48Train (Amtrak)
- Take the train from Chicago Union Station to Indianapolistrain Cardinal
6h 30m$107–178Line 303 bus to Chicago O'Hare International Airport, fly
- Take the bus from Broadway Ave & Division St to Rosemont CTA Station - Bus Stop Fbus
- Fly from Chicago O'Hare International Airport (ORD) to Indianapolis (IND)plane ORD - IND
3h 49m$506–860Bus (Flixbus)
- Take the bus from Chicago Bus Station to Indianapolisbus FlixBus 2511 / ...
6h 20m$35–51Line 309 bus to Chicago Midway International Airport, fly
- Take the bus from Lake St & 19th Ave to Lake St & Austin Blvdbus
- Fly from Chicago Midway International Airport (MDW) to Indianapolis (IND)plane MDW - IND
4h 31m$81–608
Melrose Park to Indianapolis by bus and subway (Greyhound)
Comparing Your Travel Options
The cheapest way to get from Melrose Park to Indianapolis is to drive which costs $30 - $50 and takes 3h 29m.
The fastest way to get from Melrose Park to Indianapolis is to drive which takes 3h 29m and costs $30 - $50.
No, there is no direct bus from Melrose Park to Indianapolis station. However, there are services departing from Broadway Ave & Division St and arriving at Indianapolis Union Station via Harrison & Kedzie and Chicago Bus Station. The journey, including transfers, takes approximately 5h 29m.
No, there is no direct train from Melrose Park to Indianapolis. However, there are services departing from Melrose Park and arriving at Indianapolis via Chicago Union Station. The journey, including transfers, takes approximately 6h 30m.
The distance between Melrose Park and Indianapolis is 195 miles. The road distance is 192.9 miles.
The best way to get from Melrose Park to Indianapolis without a car is to bus via Kedzie-Homan which takes 5h 29m and costs $35 - $65.
It takes approximately 5h 29m to get from Melrose Park to Indianapolis, including transfers.
Melrose Park to Indianapolis bus services, operated by Greyhound USA, depart from Chicago Bus Station.
Melrose Park to Indianapolis train services, operated by Amtrak, depart from Chicago Union Station.
The best way to get from Melrose Park to Indianapolis is to bus via Kedzie-Homan which takes 5h 29m and costs $35 - $65. Alternatively, you can train, which costs $100 - $180 and takes 6h 30m.
What companies run services between Melrose Park, IL, USA and Indianapolis, IN, USA?
Greyhound USA operates a bus from Chicago Bus Station to Indianapolis Union Station every 3 hours. Tickets cost $30–50 and the journey takes 3h 5m. Alternatively, Amtrak operates a train from Chicago Union Station to Indianapolis 3 times a week. Tickets cost $100–170 and the journey takes 4h 54m.
- Website
- united.com
Flights from Chicago O'Hare International Airport to Indianapolis
- Ave. Duration
- 1h 16m
- When
- Every day
- Estimated price
- $45–350
- Website
- aa.com
Flights from Chicago O'Hare International Airport to Indianapolis
- Ave. Duration
- 1h 13m
- When
- Every day
- Estimated price
- $45–350
- Website
- southwest.com
Flights from Chicago Midway International Airport to Indianapolis
- Ave. Duration
- 1h 2m
- When
- Every day
- Estimated price
- $75–600
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Chicago Union Station to Indianapolis
- Ave. Duration
- 4h 54m
- Frequency
- 3 times a week
- Estimated price
- $100–170
- Website
- Amtrak
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Chicago Bus Station to Indianapolis Union Station
- Ave. Duration
- 3h 5m
- Frequency
- Every 3 hours
- Estimated price
- $30–50
- Website
- Greyhound
- Phone
- +1(847) 364-7223
- [email protected]
- Website
- Pace Bus
Bus from Broadway Ave & Division St to Rosemont CTA Station - Bus Stop F
- Ave. Duration
- 25 min
- Frequency
- Hourly
- Estimated price
- $1–3
- Website
- Pace Bus
- Schedules at
- Pace Bus Routes, Schedules and Maps
- Adult
- $1–3
Bus from Lake St & 19th Ave to Lake St & Austin Blvd
- Ave. Duration
- 23 min
- Frequency
- Every 30 minutes
- Estimated price
- $1–3
- Website
- Pace Bus
- Schedules at
- Pace Bus Routes, Schedules and Maps
- Adult
- $1–3
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Chicago Bus Station to Indianapolis
- Ave. Duration
- 3h 45m
- Frequency
- Every 2 hours
- Estimated price
- $29–45
- Schedules at
- Flixbus USA
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Booking & Getting There
Melrose Park to Indianapolis bus services, operated by Greyhound USA, arrive at Indianapolis Union Station.
Indianapolis is 1h ahead of Melrose Park. It is currently 5:49 PM in Melrose Park and 6:49 PM in Indianapolis.
Melrose Park to Indianapolis train services, operated by Amtrak, arrive at Indianapolis station.
Yes, the driving distance between Melrose Park to Indianapolis is 193 miles. It takes approximately 3h 29m to drive from Melrose Park to Indianapolis.
There are 910+ hotels available in Indianapolis.






