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How to get fromMemphis Central Station to St. Louisby bus (Flixbus, Greyhound), train, bus, car, or plane

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There are 5 ways to get from Memphis Central Station to St. Louis by bus (Flixbus, Greyhound), train, bus, car, or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus

    best
    1. Take the bus from Memphis Bus Station to St Louis Bus Stationbus bus FlixBus 2510
    6h 23m
    $41–86

  2. Train, bus

    1. Take the train from Memphis to Carbondaletrain train City of New Orleans
    2. Take the bus from Carbondale to St. Louisbus bus Amtrak Thruway Connecting Service
    7h 28m
    $86–195

  3. Drive 283.4 mi

    1. Drive from Memphis Central Station to St. Louiscar car 283.4 mi
    4h 33m
    $52–75

  4. Fly from Memphis

    1. Fly from Memphis (MEM) to Lambert–St. Louis International Airport (STL)plane plane MEM - STL
    6h 34m
    $115–655

  5. Bus to Jonesboro Municipal Airport, fly

    1. Take the bus from Memphis Bus Station to Jonesborobus bus
    2. Fly from Jonesboro Municipal Airport (JBR) to Lambert–St. Louis International Airport (STL)plane plane JBR - STL
    6h 32m
    $183–588

Memphis Central Station to St. Louis by bus

Calendar14Weekly Buses
Duration6h 23mAverage Duration
Ticket$41Cheapest Price
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Questions & Answers

Map of how to get from Memphis Central Station to St. Louis.ExpandLaunch map view
  • Distance: 302.2 mi
  • Duration: 6h 23m

What companies run services between Memphis Central Station, TN, USA and St. Louis, MO, USA?

Flixbus USA operates a bus from Memphis Bus Station to St Louis Bus Station once daily. Tickets cost $45–80 and the journey takes 4h 45m. Greyhound USA also services this route once daily. Alternatively, Southwest Airlines, Delta, and two other airlines fly from Memphis (MEM) to Lambert–St. Louis International Airport (STL) hourly.

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