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How to get fromMemphis to Des Moinesby plane, bus (Greyhound, Flixbus), car, bus, train, or bus (Flixbus, Amtrak, Greyhound)

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There are 6 ways to get from Memphis to Des Moines by plane, bus (Greyhound, Flixbus), car, bus, train, or bus (Flixbus, Amtrak, Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly

    best
    1. Fly from Memphis (MEM) to Des Moines (DSM)plane plane MEM - DSM
    5h 41m
    $178–872

  2. Drive  598.4 mi

    cheapest
    1. Drive from Memphis to Des Moinescar car 598.4 mi
    10h 52m
    $110–158

  3. Bus via Kansas City

    1. Take the bus from Memphis Bus Station to St Louis Bus Stationbus bus
    2. Take the bus from St Louis Bus Station to Kansas City Bus Stationbus bus
    3. Take the bus from Kansas City to Des Moinesbus bus
    16h 23m
    $126–226

  4. Bus, train

    1. Take the bus from Memphis Bus Station to St Louis Bus Stationbus bus
    2. Take the train from St. Louis to Bloomington-Normaltrain train
    3. Take the bus from Bloomington-Normal to Des Moinesbus bus
    18h 6m
    $121–256

  5. Bus

    1. Take the bus from Memphis Bus Station to Springfield SMTD Transfer Centerbus bus
    2. Take the bus from Springfield to Galesburg Amtrak Stationbus bus
    3. Take the bus from Galesburg to Des Moinesbus bus
    18h 19m
    $117–203

  6. Bus, train via Kansas City

    1. Take the bus from Memphis Bus Station to St Louis Bus Stationbus bus
    2. Take the train from St. Louis to Kansas Citytrain train
    3. Take the bus from Kansas City Bus Station to Des Moinesbus bus
    18h 37m
    $138–306

Memphis to Des Moines by bus

Calendar12Weekly Buses
Duration16h 23mAverage Duration
Ticket$126Cheapest Price
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Questions & Answers

Map of how to get from Memphis to Des Moines.ExpandLaunch map view
  • Distance: 509.1 mi
  • Duration: 5h 41m

What companies run services between Memphis, TN, USA and Des Moines, IA, USA?

Southwest Airlines, Delta, and two other airlines fly from Memphis (MEM) to Des Moines (DSM) hourly. Alternatively, you can take a bus from 2ND STREET at ADAMS AVENUE to Des Moines via Memphis Bus Station, St Louis Bus Station, Kansas City Bus Station, and Kansas City in around 16h 23m.

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