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How to get fromMemphis to Florenceby plane, bus (Greyhound), car, bus, or train

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There are 6 ways to get from Memphis to Florence by plane, bus (Greyhound), car, bus, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Florence Regional Airport

    best
    1. Fly from Memphis (MEM) to Florence Regional Airport (FLO)plane plane MEM - FLO
    5h 41m
    $101–494
  2. Bus

    1. Take the bus from Memphis Bus Station to Atlanta Bus Stationbus bus Greyhound US0610
    2. Take the bus from Atlanta to Florencebus bus Ses 987 / ...
    15h 58m
    $106–211
  3. Drive 667.2 mi

    1. Drive from Memphis to Florencecar car 667.2 mi
    11h 7m
    $122–176
  4. Fly to Myrtle Beach, bus

    1. Fly from Memphis (MEM) to Myrtle Beach (MYR)plane plane MEM - MYR
    2. Take the bus from Myrtle Beach to Florencebus bus
    7h 42m
  5. Fly to Fayetteville Municipal Airport, train

    1. Fly from Memphis (MEM) to Fayetteville Municipal Airport (FAY)plane plane MEM - FAY
    2. Take the train from Fayetteville Amtrak Station to Florence Stationtrain train
    8h 31m
    $133–565
  6. Bus via Sumter

    1. Take the bus from Memphis Bus Station to Atlanta Bus Stationbus bus
    2. Take the bus from Atlanta to Sumterbus bus
    3. Take the bus from Sumter Bus Stop to Florence Bus Stationbus bus
    17h 28m

Memphis to Florence by bus

Calendar28Weekly Buses
Duration15h 58mAverage Duration
Ticket$106Cheapest Price
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Questions & Answers

What companies run services between Memphis, TN, USA and Florence, SC, USA?

American Airlines flies from Memphis (MEM) to Florence Regional Airport (FLO) once daily. Alternatively, you can take a bus from 2ND STREET at ADAMS AVENUE to Florence via Memphis Bus Station and Atlanta in around 15h 58m.

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