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How to get fromMemphis to Saint Charlesby bus (Greyhound, Flixbus), car, or plane

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There are 3 ways to get from Memphis to Saint Charles by bus (Greyhound, Flixbus), car, or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus

    best
    1. Take the bus from Memphis Bus Station to St Louis Bus Stationbus bus Greyhound US1173
    8h 23m
    $45–85

  2. Drive 295.8 mi

    1. Drive from Memphis to Saint Charlescar car 295.8 mi
    4h 47m
    $54–78

  3. Fly

    1. Fly from Memphis (MEM) to Lambert–St. Louis International Airport (STL)plane plane MEM - STL
    5h 43m
    $105–605

Memphis to Saint Charles by bus and train

Calendar12Weekly Services
Duration8h 23mAverage Duration
Ticket$45Cheapest Price
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Questions & Answers

Map of how to get from Memphis to Saint Charles.ExpandLaunch map view
  • Distance: 326.6 mi
  • Duration: 8h 23m

What companies run services between Memphis, TN, USA and Saint Charles, MO, USA?

Greyhound USA operates a bus from Memphis Bus Station to St Louis Bus Station once daily. Tickets cost $40–80 and the journey takes 5h 15m. Flixbus USA also services this route 5 times a week. Alternatively, Southwest Airlines, Delta, and two other airlines fly from Memphis (MEM) to Lambert–St. Louis International Airport (STL) hourly.

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