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How to get fromMemphis to Saint Charlesby bus (Flixbus, Greyhound), car, or plane

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There are 3 ways to get from Memphis to Saint Charles by bus (Flixbus, Greyhound), car, or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus

    best
    1. Take the bus from Memphis Bus Station to St Louis Bus Stationbus bus FlixBus 2510
    7h 53m
    $50–95

  2. Drive 295.8 mi

    1. Drive from Memphis to Saint Charlescar car 295.8 mi
    4h 47m
    $54–78

  3. Fly

    1. Fly from Memphis (MEM) to Lambert–St. Louis International Airport (STL)plane plane MEM - STL
    5h 42m
    $115–655

Memphis to Saint Charles by bus and train

Calendar14Weekly Services
Duration7h 53mAverage Duration
Ticket$50Cheapest Price
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Questions & Answers

Map of how to get from Memphis to Saint Charles.ExpandLaunch map view
  • Distance: 325 mi
  • Duration: 7h 53m

What companies run services between Memphis, TN, USA and Saint Charles, MO, USA?

Flixbus USA operates a bus from Memphis Bus Station to St Louis Bus Station once daily. Tickets cost $45–80 and the journey takes 4h 45m. Greyhound USA also services this route once daily. Alternatively, Southwest Airlines, Delta, and two other airlines fly from Memphis (MEM) to Lambert–St. Louis International Airport (STL) hourly.

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