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How to get fromMemphis to St. Louisby bus (Greyhound, Flixbus), car, or plane

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There are 3 ways to get from Memphis to St. Louis by bus (Greyhound, Flixbus), car, or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus

    best
    1. Take the bus from Memphis Bus Station to St Louis Bus Stationbus bus Greyhound US1173
    6h 58m
    $41–86

  2. Drive 283.3 mi

    1. Drive from Memphis to St. Louiscar car 283.3 mi
    4h 33m
    $52–75

  3. Fly

    1. Fly from Memphis (MEM) to Lambert–St. Louis International Airport (STL)plane plane MEM - STL
    5h 18m
    $104–654

Memphis to St. Louis by bus

Calendar12Weekly Buses
Duration6h 58mAverage Duration
Ticket$41Cheapest Price
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Questions & Answers

Map of how to get from Memphis to St. Louis.ExpandLaunch map view
  • Distance: 305.2 mi
  • Duration: 6h 58m

What companies run services between Memphis, TN, USA and St. Louis, MO, USA?

Greyhound USA operates a bus from Memphis Bus Station to St Louis Bus Station once daily. Tickets cost $40–85 and the journey takes 5h 15m. Flixbus USA also services this route 5 times a week. Alternatively, Southwest Airlines, Delta, and two other airlines fly from Memphis (MEM) to Lambert–St. Louis International Airport (STL) hourly.

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