There are 6 ways to get from Memphis to Winston-Salem by plane, bus (Greyhound), car, bus, or bus (Greyhound, Flixbus)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly to Piedmont Triad International Airport
best- Fly from Memphis (MEM) to Piedmont Triad International Airport (GSO)plane MEM - GSO
6h 3m$100–494Bus (Greyhound)
- Take the bus from Memphis Bus Station to Atlanta Bus Stationbus Greyhound US0610
- Take the bus from Atlanta Bus Station to Winston Salem(Trans Center)bus Greyhound US0670
16h 41m$126–201Drive 628.1 mi
- Drive from Memphis to Winston-Salemcar 628.1 mi
11h 5m$108–156Fly to Charlotte Douglas International Airport, bus
- Fly from Memphis (MEM) to Charlotte Douglas International Airport (CLT)plane MEM - CLT
- Take the bus from Charlotte Bus Station to Winston Salem(Trans Center)bus
6h 27m$139–778Fly to Raleigh-Durham International Airport, bus
- Fly from Memphis (MEM) to Raleigh-Durham International Airport (RDU)plane MEM - RDU
- Take the bus from Durham to Winston Salem(Trans Center)bus
7h 39m$141–729Bus via Charlotte
- Take the bus from Memphis Bus Station to Atlanta Bus Stationbus
- Take the bus from Atlanta Downtown to Charlotte Bus Stationbus
- Take the bus from Charlotte Bus Station to Winston Salem(Trans Center)bus
17h 5m$123–195
Memphis to Winston-Salem by bus (Greyhound)
Comparing Your Travel Options
The cheapest way to get from Memphis to Winston-Salem is to drive which costs $100 - $160 and takes 11h 5m.
The fastest way to get from Memphis to Winston-Salem is to fly which takes 6h 3m and costs $100 - $500.
No, there is no direct bus from Memphis to Winston-Salem. However, there are services departing from 2ND STREET at ADAMS AVENUE and arriving at Winston Salem(Trans Center) via Memphis Bus Station and Atlanta Bus Station. The journey, including transfers, takes approximately 16h 41m.
The distance between Memphis and Winston-Salem is 608 miles. The road distance is 631.7 miles.
The best way to get from Memphis to Winston-Salem without a car is to bus which takes 16h 41m and costs $120 - $210.
It takes approximately 6h 3m to get from Memphis to Winston-Salem, including transfers.
Memphis to Winston-Salem bus services, operated by Greyhound USA, depart from Memphis Bus Station.
The best way to get from Memphis to Winston-Salem is to fly which takes 6h 3m and costs $100 - $500. Alternatively, you can bus, which costs $120 - $210 and takes 16h 41m.
Memphis to Winston-Salem bus services, operated by Greyhound USA, arrive at Atlanta Bus Station.
Winston-Salem is 1h ahead of Memphis. It is currently 10:57 PM in Memphis and 11:57 PM in Winston-Salem.
What companies run services between Memphis, TN, USA and Winston-Salem, NC, USA?
Delta, American Airlines, and United Airlines fly from Memphis (MEM) to Piedmont Triad International Airport (GSO) every 2 hours. Alternatively, you can take a bus from 2ND STREET at ADAMS AVENUE to Winston Salem(Trans Center) via Memphis Bus Station and Atlanta Bus Station in around 16h 41m.
- Website
- delta.com
Flights from Memphis to Piedmont Triad International Airport via Atlanta
- Ave. Duration
- 4h 12m
- When
- Every day
- Estimated price
- $85–480
Flights from Memphis to Piedmont Triad International Airport via Detroit
- Ave. Duration
- 6h 1m
- When
- Every day
- Estimated price
- $120–600
Flights from Memphis to Charlotte Douglas International Airport via Atlanta
- Ave. Duration
- 3h 45m
- When
- Every day
- Estimated price
- $130–750
Flights from Memphis to Raleigh-Durham International Airport via Atlanta
- Ave. Duration
- 4h 2m
- When
- Every day
- Estimated price
- $120–700
- Website
- aa.com
Flights from Memphis to Piedmont Triad International Airport via Charlotte Douglas International Airport
- Ave. Duration
- 4h 4m
- When
- Every day
- Estimated price
- $80–470
Flights from Memphis to Piedmont Triad International Airport via Reagan Washington
- Ave. Duration
- 5h 37m
- When
- Sunday and Saturday
- Estimated price
- $110–600
Flights from Memphis to Piedmont Triad International Airport via Chicago O'Hare
- Ave. Duration
- 6h 40m
- When
- Every day
- Estimated price
- $120–600
Flights from Memphis to Charlotte Douglas International Airport
- Ave. Duration
- 1h 54m
- When
- Every day
- Estimated price
- $120–750
Flights from Memphis to Raleigh-Durham International Airport via Charlotte Douglas International Airport
- Ave. Duration
- 4h 16m
- When
- Thursday, Friday, and Sunday
- Estimated price
- $120–700
- Website
- southwest.com
Flights from Memphis to Charlotte Douglas International Airport via Nashville
- Ave. Duration
- 3h 37m
- When
- Monday, Thursday, Friday, and Sunday
- Estimated price
- $120–750
Flights from Memphis to Raleigh-Durham International Airport via Nashville
- Ave. Duration
- 3h 57m
- When
- Tuesday, Wednesday, Monday, Thursday, Friday, and Sunday
- Estimated price
- $120–700
- Website
- united.com
Flights from Memphis to Piedmont Triad International Airport via Chicago O'Hare
- Ave. Duration
- 6h 1m
- When
- Every day
- Estimated price
- $120–600
- Website
- flybreeze.com
Flights from Memphis to Raleigh-Durham International Airport
- Ave. Duration
- 1h 56m
- When
- Monday and Friday
- Estimated price
- $250–1,500
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Memphis Bus Station to Atlanta Bus Station
- Ave. Duration
- 7h 35m
- Frequency
- 4 times a day
- Estimated price
- $70–110
- Website
- Greyhound
Bus from Atlanta Bus Station to Winston Salem(Trans Center)
- Ave. Duration
- 6h 20m
- Frequency
- 4 times a day
- Estimated price
- $55–90
- Website
- Greyhound
Bus from Charlotte Bus Station to Winston Salem(Trans Center)
- Ave. Duration
- 1h 25m
- Frequency
- 4 times a day
- Estimated price
- $14–21
- Website
- Greyhound
Bus from Durham to Winston Salem(Trans Center)
- Ave. Duration
- 1h 45m
- Frequency
- Every 4 hours
- Estimated price
- $14–22
- Website
- Greyhound
Bus from Memphis Bus Station to Atlanta Bus Station
- Ave. Duration
- 7h 35m
- Frequency
- 4 times a day
- Estimated price
- $70–110
- Website
- Greyhound
Bus from Charlotte Bus Station to Winston Salem(Trans Center)
- Ave. Duration
- 1h 25m
- Frequency
- 4 times a day
- Estimated price
- $14–21
- Website
- Greyhound
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Atlanta Downtown to Charlotte Bus Station
- Ave. Duration
- 4h 10m
- Frequency
- Once daily
- Estimated price
- $35–60
- Schedules at
- Flixbus USA
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Booking & Getting There
Yes, the driving distance between Memphis to Winston-Salem is 632 miles. It takes approximately 11h 5m to drive from Memphis to Winston-Salem.
Book your Memphis to Winston-Salem bus tickets online with Omio.
There are 151+ hotels available in Winston-Salem.



