There are 6 ways to get from Mendon to Hyannis by train, bus, car, plane, or bus (Greyhound)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train, bus
best- Take the train from Forge Park/495 to South Stationtrain Franklin/Foxboro Line
- Take the bus from Boston South Buses to Hyannis Transportation Centerbus Hyannis - South Shore to Logan Airport
3h 53m$54–74Drive 79.5 mi
cheapest- Drive from Mendon to Hyanniscar 79.5 mi
1h 38m$15–21Train, fly
- Take the train from Forge Park/495 to Back Baytrain
- Fly from Boston Logan Airport (BOS) to Barnstable Municipal Airport (HYA)plane BOS - HYA
3h 38m$156–357Train, bus via Boston
- Take the train from Forge Park/495 to South Stationtrain Franklin/Foxboro Line
- Take the bus from Boston to Hyannisbus Bz 0956 / ...
4h$41–64Bus, train
- Take the bus from Milford Library to Framingham MBTA Stationbus
- Take the train from Framingham to South Stationtrain
- Take the bus from Boston South Buses to Hyannis Transportation Centerbus
5h 7m$45–61Bus
- Take the bus from Framingham to Bostonbus Greyhound US0270s
- Take the bus from Boston South Buses to Hyannis Transportation Centerbus Hyannis - South Shore to Logan Airport
5h 7m$49–63
Boston Logan Airport (BOS) to Barnstable Municipal Airport (HYA) flights
Comparing Your Travel Options
The cheapest way to get from Mendon to Hyannis is to drive which costs $14 - $21 and takes 1h 38m.
The fastest way to get from Mendon to Hyannis is to drive which takes 1h 38m and costs $14 - $21.
No, there is no direct bus from Mendon to Hyannis. However, there are services departing from Milford Crossing and arriving at Hyannis Transportation Center via Framingham and Boston South Buses. The journey, including transfers, takes approximately 5h 7m.
The distance between Mendon and Hyannis is 111 miles. The road distance is 80 miles.
The best way to get from Mendon to Hyannis without a car is to train and bus which takes 3h 53m and costs $50 - $75.
It takes approximately 3h 53m to get from Mendon to Hyannis, including transfers.
Mendon to Hyannis bus services, operated by Greyhound USA, depart from Framingham station.
Mendon to Hyannis bus services, operated by Greyhound USA, arrive at Boston station.
Yes, the driving distance between Mendon to Hyannis is 80 miles. It takes approximately 1h 38m to drive from Mendon to Hyannis.
There are 820+ hotels available in Hyannis.
What companies run services between Mendon, MA, USA and Hyannis, MA, USA?
You can take a vehicle from Mendon to Hyannis Transportation Center via Milford Crossing, Framingham MBTA Station, Framingham, Boston, and Boston South Buses in around 5h 7m.
- Website
- capeair.com
Flights from Boston Logan Airport to Barnstable Municipal Airport
- Ave. Duration
- 45 min
- When
- Every day
- Estimated price
- $120–310
Flights from Boston Logan Airport to Barnstable Municipal Airport via Nantucket
- Ave. Duration
- 2h 24m
- When
- Saturday and Sunday
- Estimated price
- $120–310
Train from Forge Park/495 to South Station
- Ave. Duration
- 1h 9m
- Frequency
- Every 2 hours
- Estimated price
- $5–12
- Website
- Massachusetts Bay Transportation Authority
- Website
- MBTA: World Cup 2026
- Adult
- $5–12
Train from Forge Park/495 to Back Bay
- Ave. Duration
- 58 min
- Frequency
- Every 4 hours
- Estimated price
- $5–11
- Website
- Massachusetts Bay Transportation Authority
- Website
- MBTA: World Cup 2026
- Adult
- $5–11
Train from Forge Park/495 to South Station
- Ave. Duration
- 1h 9m
- Frequency
- Every 2 hours
- Estimated price
- $5–12
- Website
- Massachusetts Bay Transportation Authority
- Website
- MBTA: World Cup 2026
- Adult
- $5–12
Train from Framingham to South Station
- Ave. Duration
- 56 min
- Frequency
- Hourly
- Estimated price
- $4–10
- Website
- Massachusetts Bay Transportation Authority
- Website
- MBTA: World Cup 2026
- Adult
- $4–10
- Phone
- +1 (508) 746-0378
- [email protected]
- Website
- Plymouth & Brockton
Bus from Boston South Buses to Hyannis Transportation Center
- Ave. Duration
- 1h 50m
- Frequency
- Hourly
- Estimated price
- $27–35
- Website
- Plymouth & Brockton
- One Way - Adult
- $27–35
Bus from Boston South Buses to Hyannis Transportation Center
- Ave. Duration
- 1h 50m
- Frequency
- Hourly
- Estimated price
- $27–35
- Website
- Plymouth & Brockton
- One Way - Adult
- $27–35
Bus from Boston South Buses to Hyannis Transportation Center
- Ave. Duration
- 1h 50m
- Frequency
- Hourly
- Estimated price
- $27–35
- Website
- Plymouth & Brockton
- One Way - Adult
- $27–35
- Phone
- 1-800-343-9999
- Website
- Peter Pan
Bus from Boston to Hyannis
- Ave. Duration
- 1h 40m
- Frequency
- Every 3 hours
- Estimated price
- $14–25
- Website
- Peter Pan
Bus from Milford Library to Framingham MBTA Station
- Ave. Duration
- 56 min
- Frequency
- Every 3 hours
- Estimated price
- $2
- Website
- MetroWest Regional Transit Authority
- Schedules at
- MetroWest Regional Transit Authority Fixed Routes
- Seniors 65+
- $1
- Students 6-18
- $1
- Adult
- $2
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Framingham to Boston
- Ave. Duration
- 50 min
- Frequency
- Once daily
- Estimated price
- $3–6
- Website
- Greyhound
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