There are 5 ways to get from Mendoza to Santa Cruz by bus, car, plane, or bus (Flixbus)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus
best- Take the bus from Terminal Mendoza to Terminal Sur de Santiagobus Santiago
- Take the bus from Terminal Sur de Santiago to Terminal de Buses Santa Cruzbus Santiago
9h 6m$19–53Bus via Hospital
cheapest- Take the bus from Terminal Mendoza to Terminal Alameda - Turbusbus Mendoza
- Take the bus from Terminal Sur de Santiago to Hospitalbus Santiago
11h 11m$18–83Drive 519.6 km
- Drive from Mendoza to Santa Cruzcar 519.6 km
6h 45m$65–93Fly, bus
- Fly from Governor Francisco Gabrielli International Airport (MDZ) to Comodoro Arturo Merino Benítez International Airport (SCL)plane MDZ - SCL
- Take the bus from Terminal Sur de Santiago to Santa Cruzbus
7h$69–252Bus via Santa Cruz
- Take the bus from Terminal Mendoza to Terminal Sur de Santiagobus Santiago
- Take the bus from Terminal Sur de Santiago to Santa Cruzbus FlixBus CL027
9h 7m$26–75
Mendoza to Santa Cruz by bus
Questions & Answers
The cheapest way to get from Mendoza to Santa Cruz is to bus which costs $19 - $55 and takes 9h 6m.
The fastest way to get from Mendoza to Santa Cruz is to drive which takes 6h 45m and costs $60 - $95.
No, there is no direct bus from Mendoza to Santa Cruz. However, there are services departing from Terminal Mendoza and arriving at Terminal de Buses Santa Cruz via Terminal Sur de Santiago. The journey, including transfers, takes approximately 9h 6m.
The distance between Mendoza and Santa Cruz is 534 km. The road distance is 519.6 km.
The best way to get from Mendoza to Santa Cruz without a car is to bus which takes 9h 6m and costs $19 - $55.
It takes approximately 9h 6m to get from Mendoza to Santa Cruz, including transfers.
Mendoza to Santa Cruz bus services, operated by Chi-Ar Internacional, depart from Terminal Mendoza station.
Mendoza to Santa Cruz bus services, operated by Chi-Ar Internacional, arrive at Terminal Sur de Santiago station.
Santa Cruz is 1h behind Mendoza. It is currently 6:07 AM in Mendoza and 5:07 AM in Santa Cruz.
Yes, the driving distance between Mendoza to Santa Cruz is 520 km. It takes approximately 6h 45m to drive from Mendoza to Santa Cruz.
What companies run services between Mendoza, Argentina and Santa Cruz, O'Higgins, Chile?
You can take a bus from Terminal Mendoza to Terminal de Buses Santa Cruz via Terminal Sur de Santiago in around 9h 6m.
- Website
- jetsmart.com
Flights from Governor Francisco Gabrielli International Airport to Comodoro Arturo Merino Benítez International Airport
- Ave. Duration
- 1h 6m
- When
- Every day
- Estimated price
- $55–160
- Website
- skyairline.com
Flights from Governor Francisco Gabrielli International Airport to Comodoro Arturo Merino Benítez International Airport
- Ave. Duration
- 1h 3m
- When
- Every day
- Estimated price
- $55–180
- Website
- latam.com
Flights from Governor Francisco Gabrielli International Airport to Comodoro Arturo Merino Benítez International Airport
- Ave. Duration
- 1h
- When
- Every day
- Estimated price
- $70–270
- Phone
- +56 9 5950 0854
- [email protected]
- Website
- Chi-Ar Internacional
Bus from Terminal Mendoza to Terminal Sur de Santiago
- Ave. Duration
- 6h
- Frequency
- Twice daily
- Estimated price
- $38
- Schedules at
- Chi-Ar Internacional
Bus from Terminal Mendoza to Terminal Sur de Santiago
- Ave. Duration
- 6h
- Frequency
- Twice daily
- Estimated price
- $38
- Schedules at
- Chi-Ar Internacional
- Phone
- 0800 122 2282
- [email protected]
- Website
- Cata International
Bus from Terminal Mendoza to Terminal Sur de Santiago
- Ave. Duration
- 9h
- Frequency
- Twice daily
- Estimated price
- $18–44
- Website
- Cata International
- Ejecutivo
- $23–35
- Semi Cama
- $18–26
- Ejecutivo Individual
- $26–35
Bus from Terminal Mendoza to Terminal Sur de Santiago
- Ave. Duration
- 9h
- Frequency
- Twice daily
- Estimated price
- $18–44
- Website
- Cata International
- Ejecutivo
- $23–35
- Semi Cama
- $18–26
- Ejecutivo Individual
- $26–35
- Phone
- 0810 122 1122
- [email protected]
- Website
- andesmar.com
Bus from Terminal Mendoza to Terminal Sur de Santiago
- Ave. Duration
- 9h
- Frequency
- Twice daily
- Estimated price
- $15–41
- Schedules at
- andesmar.com
- Book at
- andesmar.com
- Bed
- $18–26
- Semi bed
- $15–21
Bus from Terminal Mendoza to Terminal Sur de Santiago
- Ave. Duration
- 9h
- Frequency
- Twice daily
- Estimated price
- $15–41
- Schedules at
- andesmar.com
- Book at
- andesmar.com
- Bed
- $18–26
- Semi bed
- $15–21
- Phone
- +56 9 7242 8977
- [email protected]
- Website
- mathostour.cl
Bus from Terminal Mendoza to Terminal Sur de Santiago
- Ave. Duration
- 8h 30m
- Frequency
- Once daily
- Estimated price
- $38
- Schedules at
- mathostour.cl
- Book at
- kupos.cl
Bus from Terminal Mendoza to Terminal Sur de Santiago
- Ave. Duration
- 8h 30m
- Frequency
- Once daily
- Estimated price
- $38
- Schedules at
- mathostour.cl
- Book at
- kupos.cl
- Phone
- 0810 122 1122
- [email protected]
- Website
- COITRAM
Bus from Terminal Mendoza to Terminal Sur de Santiago
- Ave. Duration
- 7h
- Frequency
- Twice a week
- Estimated price
- $34
- Schedules at
- COITRAM
Bus from Terminal Mendoza to Terminal Sur de Santiago
- Ave. Duration
- 7h
- Frequency
- Twice a week
- Estimated price
- $34
- Schedules at
- COITRAM
- [email protected]
- Website
- Expreso Santa Cruz
Bus from Terminal Sur de Santiago to Terminal de Buses Santa Cruz
- Ave. Duration
- 3h
- Frequency
- Every 30 minutes
- Estimated price
- $7
- Schedules at
- Expreso Santa Cruz
- Phone
- +56 22 683 8528
- [email protected]
- Website
- Andimar
Bus from Terminal Sur de Santiago to Terminal de Buses Santa Cruz
- Ave. Duration
- 2h 50m
- Frequency
- Hourly
- Estimated price
- $4–11
- Schedules at
- Andimar
- Semi Cama
- $4–9
- Cama
- $5–11
Bus from Terminal Sur de Santiago to Hospital
- Ave. Duration
- 2h 41m
- Frequency
- Hourly
- Estimated price
- $4–11
- Schedules at
- Andimar
- Semi Cama
- $4–8
- Cama
- $5–11
Bus from Terminal Sur de Santiago to Terminal de Buses Santa Cruz
- Ave. Duration
- 3h 20m
- Frequency
- Every 30 minutes
- Estimated price
- $4–11
- Schedules at
- TranSantin
- Road
- $4–11
- Phone
- +56 2 2666 5505
- [email protected]
- Website
- Buses Jetsur
Bus from Terminal Sur de Santiago to Terminal de Buses Santa Cruz
- Ave. Duration
- 3h 13m
- Frequency
- 4 times a day
- Estimated price
- $10–13
- Website
- Buses Jetsur
- Website
- Flixbus Chile
Bus from Terminal Sur de Santiago to Santa Cruz
- Ave. Duration
- 2h 40m
- Frequency
- Hourly
- Estimated price
- $19–35
- Schedules at
- Flixbus Chile
Bus from Terminal Sur de Santiago to Santa Cruz
- Ave. Duration
- 2h 40m
- Frequency
- Hourly
- Estimated price
- $19–35
- Schedules at
- Flixbus Chile
- Phone
- +56 600 600 0018
- [email protected]
- Website
- pullmanbus.cl
Bus from Terminal Sur de Santiago to Santa Cruz
- Ave. Duration
- 3h
- Frequency
- 4 times a day
- Estimated price
- $12–35
- Schedules at
- pullmanbus.cl
- Book at
- pullmanbus.cl
- Salón Cama
- $14–35
Bus from Terminal Sur de Santiago to Santa Cruz
- Ave. Duration
- 3h
- Frequency
- 4 times a day
- Estimated price
- $12–35
- Schedules at
- pullmanbus.cl
- Book at
- pullmanbus.cl
- Salón Cama
- $14–35
- Phone
- +56 22 822 7500
- [email protected]
- Website
- turbus.cl
Bus from Terminal Mendoza to Terminal Alameda - Turbus
- Semi Cama
- $13–20
- Cama
- $18–25
- Premium
- $60–75
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