There are 4 ways to get from Mendoza to Santa Cruz de la Sierra by plane, bus, or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly
best- Fly from Governor Francisco Gabrielli International Airport (MDZ) to Viru Viru International Airport (VVI)plane MDZ - VVI
9h$263–555Bus via Santiago
cheapest- Take the bus from Terminal Mendoza to Terminal Sur de Santiagobus Santiago
- Take the bus from Terminal Alameda - Turbus to Santa Cruzbus Santa Cruz
47h$59–84Bus
- Take the bus from Terminal Mendoza to Santa Cruzbus
31h$100–150Drive 2,110.9 km
- Drive from Mendoza to Santa Cruz de la Sierracar 2,110.9 km
26h 21m$189–272
Governor Francisco Gabrielli International Airport (MDZ) to Viru Viru International Airport (VVI) flights
Questions & Answers
The cheapest way to get from Mendoza to Santa Cruz de la Sierra is to bus via Santiago which costs $55 - $85 and takes 47h.
The fastest way to get from Mendoza to Santa Cruz de la Sierra is to fly which takes 9h and costs $260 - $600.
Yes, there is a direct bus departing from Terminal Mendoza and arriving at Santa Cruz. Services depart twice a week, and operate every day. The journey takes approximately 31h.
The distance between Mendoza and Santa Cruz de la Sierra is 1811 km. The road distance is 2110.9 km.
The best way to get from Mendoza to Santa Cruz de la Sierra without a car is to bus which takes 31h and costs $100 - $150.
It takes approximately 9h to get from Mendoza to Santa Cruz de la Sierra, including transfers.
Mendoza to Santa Cruz de la Sierra bus services, operated by Autobuses Quirquincho, depart from Terminal Mendoza station.
The best way to get from Mendoza to Santa Cruz de la Sierra is to fly which takes 9h and costs $260 - $600. Alternatively, you can bus, which costs $100 - $150 and takes 31h.
Mendoza to Santa Cruz de la Sierra bus services, operated by Autobuses Quirquincho, arrive at Santa Cruz station.
Santa Cruz de la Sierra is 1h behind Mendoza. It is currently 3:59 AM in Mendoza and 2:59 AM in Santa Cruz de la Sierra.
What companies run services between Mendoza, Argentina and Santa Cruz de la Sierra, Bolivia?
Aerolíneas Argentinas, LATAM Chile, and three other airlines fly from Governor Francisco Gabrielli International Airport (MDZ) to Viru Viru International Airport (VVI) once daily. Alternatively, Autobuses Quirquincho operates a bus from Terminal Mendoza to Santa Cruz twice a week. Tickets cost $100–150 and the journey takes 31h.
- Website
- boa.bo
Flights from Governor Francisco Gabrielli International Airport to Viru Viru International Airport via Ezeiza
- Ave. Duration
- 6h 8m
- When
- Wednesday and Monday
- Estimated price
- $280–800
Flights from Governor Francisco Gabrielli International Airport to Viru Viru International Airport via Sao Paulo
- Ave. Duration
- 7h 5m
- When
- Thursday, Friday, and Sunday
- Estimated price
- $310–1,000
Flights from Governor Francisco Gabrielli International Airport to Viru Viru International Airport via Rio De Janeiro-Galeao
- Ave. Duration
- 7h 40m
- When
- Friday and Sunday
- Estimated price
- $320–950
- Website
- aerolineas.com.ar
Flights from Governor Francisco Gabrielli International Airport to Viru Viru International Airport via Buenos Aires Jorge Newbery
- Ave. Duration
- 8h 10m
- When
- Friday
- Estimated price
- $250–470
Flights from Governor Francisco Gabrielli International Airport to Viru Viru International Airport via Cordoba, Buenos Aires Jorge Newbery
- Ave. Duration
- 11h 5m
- When
- Friday
- Estimated price
- $250–470
- Website
- latam.com
Flights from Governor Francisco Gabrielli International Airport to Viru Viru International Airport via Santiago
- Ave. Duration
- 13h 6m
- When
- Tuesday
- Estimated price
- $200–750
- Phone
- +59171291772
- Website
- Autobuses Quirquincho
Bus from Terminal Mendoza to Santa Cruz
- Ave. Duration
- 31h
- Frequency
- Twice a week
- Estimated price
- $100–150
- Schedules at
- Autobuses Quirquincho
- Phone
- +56 9 5950 0854
- [email protected]
- Website
- Chi-Ar Internacional
Bus from Terminal Mendoza to Terminal Sur de Santiago
- Ave. Duration
- 6h
- Frequency
- Twice daily
- Estimated price
- $39
- Schedules at
- Chi-Ar Internacional
- Phone
- 0800 122 2282
- [email protected]
- Website
- Cata International
Bus from Terminal Mendoza to Terminal Sur de Santiago
- Ave. Duration
- 9h
- Frequency
- Twice daily
- Estimated price
- $18–44
- Website
- Cata International
- Ejecutivo
- $23–35
- Semi Cama
- $18–26
- Ejecutivo Individual
- $26–35
- Phone
- 0810 122 1122
- [email protected]
- Website
- andesmar.com
Bus from Terminal Mendoza to Terminal Sur de Santiago
- Ave. Duration
- 9h
- Frequency
- Twice daily
- Estimated price
- $15–40
- Schedules at
- andesmar.com
- Book at
- andesmar.com
- Bed
- $18–26
- Semi bed
- $15–21
- Phone
- +56 9 7242 8977
- [email protected]
- Website
- mathostour.cl
Bus from Terminal Mendoza to Terminal Sur de Santiago
- Ave. Duration
- 8h 30m
- Frequency
- Once daily
- Estimated price
- $39
- Schedules at
- mathostour.cl
- Book at
- kupos.cl
- Phone
- 0810 122 1122
- [email protected]
- Website
- COITRAM
Bus from Terminal Mendoza to Terminal Sur de Santiago
- Ave. Duration
- 7h
- Frequency
- Twice a week
- Estimated price
- $34
- Schedules at
- COITRAM
- Phone
- +591 2527 7355
- [email protected]
- Website
- Jet Nort Super Class
Bus from Terminal Alameda - Turbus to Santa Cruz
- Ave. Duration
- 40h
- Frequency
- 4 times a week
- Estimated price
- $44
- Schedules at
- Jet Nort Super Class
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More Questions & Answers
Yes, the driving distance between Mendoza to Santa Cruz de la Sierra is 2111 km. It takes approximately 26h 21m to drive from Mendoza to Santa Cruz de la Sierra.
There are 726+ hotels available in Santa Cruz de la Sierra.




















