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How to get fromMendrisio to Brusselsby train, plane, train (Trenitalia), bus, car, or train (Trenitalia, TGV)

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There are 9 ways to get from Mendrisio to Brussels by train, plane, train (Trenitalia), bus, car, or train (Trenitalia, TGV)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train to Milano Malpensa Airport, fly to Brussels Airport

    best
    1. Take the train from Mendrisio to Malpensa Aeroporto T1train train
    2. Fly from Milano Malpensa Airport (MXP) to Brussels Airport (BRU)plane plane MXP - BRU
    4h 53m
    €72–250

  2. Train to Milan Linate Airport, fly to Brussels Airport

    cheapest
    1. Take the train from Mendrisio to Monzatrain train
    2. Fly from Milan Linate Airport (LIN) to Brussels Airport (BRU)plane plane LIN - BRU
    5h 24m
    €43–223

  3. Train via Frankfurt Airport (FRA)

    1. Take the train from Lugano to Basel SBBtrain train Ec
    2. Take the train from Basel SBB to Mannheim, Hauptbahnhoftrain train 12 / ...
    3. Take the train from Mannheim, Hauptbahnhof to Frankfurttrain train 47 / ...
    4. Take the train from Frankfurt to Brussels-Nordtrain train 79
    11h 4m
    €137–415

  4. Bus via Lugano

    1. Take the bus from Lugano to Brussels - Midi Train Stationbus bus BlaBlaCar Bus
    13h 3m
    €61–106

  5. Drive  812.1 km

    1. Drive from Mendrisio to Brusselscar car 812.1 km
    8h 24m
    €147–212

  6. Train to Zurich Airport, fly to Brussels Airport

    1. Take the train from Lugano to Zuerich Hbtrain train
    2. Fly from Zurich Airport (ZRH) to Brussels Airport (BRU)plane plane ZRH - BRU
    6h 30m
    €138–341

  7. Train, bus to Il Caravaggio International Airport, fly to Brussels South Charleroi Airport

    1. Take the train from Mendrisio to Milano Centraletrain train
    2. Take the bus from Piazza Luigi di Savoia to Milan Bergamo Orio al Serio Airportbus bus
    3. Fly from Il Caravaggio International Airport (BGY) to Brussels South Charleroi Airport (CRL)plane plane BGY - CRL
    4. Take the train from Charleroi-Central to Bruxelles-Centraltrain train
    7h 9m
    €67–279

  8. Train

    1. Take the train from Lugano to Basel SBBtrain train Ec
    2. Take the train from Mulhouse Ville to Luxembourgtrain train Tgv
    3. Take the train from Luxembourg to Bruxelles-Centraltrain train Ic / ...
    12h 51m
    €130–298

  9. Bus

    1. Take the bus from Como to Bruxelles - Rue du Progrèsbus bus
    16h 1m
    €134–196

Mendrisio to Brussels by train

Calendar70Weekly Trains
Duration11h 4mAverage Duration
Ticket€137Cheapest Price
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Comparing Your Travel Options

Map of how to get from Mendrisio to Brussels.ExpandLaunch map view
  • Distance: 735 km
  • Duration: 4h 53m

What companies run services between Mendrisio, Switzerland and Brussels, Belgium?

You can take a train from Mendrisio to Brussels-Nord via Lugano, Basel SBB, Mannheim, Hauptbahnhof, and Frankfurt in around 11h 4m. Alternatively, BlaBlaCar Bus operates a bus from Lugano to Brussels - Midi Train Station 4 times a day. Tickets cost €55–95 and the journey takes 11h 30m.

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