There are 6 ways to get from Mendrisio to Florence by train (Trenitalia), bus, car, train, or plane
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train
best- Take the train from Mendrisio to Milano Centraletrain Re80
- Take the train from Milano Centrale to Firenze S.M.N.train Fr
3h 12m€51–155Bus
- Take the bus from Como to Florence Villa Constanza Bus Stationbus
5h 25mDrive 354.3 km
- Drive from Mendrisio to Florencecar 354.3 km
3h 34m€62–90Train to Milano Malpensa Airport, fly
- Take the train from Mendrisio to Malpensa Aeroporto T1train
- Fly from Milano Malpensa Airport (MXP) to Florence Peretola Airport (FLR)plane MXP - FLR
6h 7m€97–257Train via Firenze Santa Maria Novella
- Take the train from Mendrisio to Milano Centraletrain Re80
- Take the train from Milano Centrale to Firenze Santa Maria Novellatrain 8111 / ...
4h 4m€56–145Train to Milan Linate Airport, fly
- Take the train from Mendrisio to Monzatrain
- Fly from Milan Linate Airport (LIN) to Florence Peretola Airport (FLR)plane LIN - FLR
5h 29m€118–281
Mendrisio to Florence by train
Questions & Answers
The cheapest way to get from Mendrisio to Florence is to train which costs €50 - €160 and takes 3h 12m.
The fastest way to get from Mendrisio to Florence is to train which takes 3h 12m and costs €50 - €160.
No, there is no direct bus from Mendrisio to Florence station. However, there are services departing from Mendrisio, Autosilo and arriving at Florence Villa Constanza Bus Station via Como - Franscini and Como. The journey, including transfers, takes approximately 5h 25m.
No, there is no direct train from Mendrisio to Florence. However, there are services departing from Mendrisio and arriving at Firenze S.M.N. via Milano Centrale. The journey, including transfers, takes approximately 3h 12m.
The distance between Mendrisio and Florence is 363 km. The road distance is 354.3 km.
The best way to get from Mendrisio to Florence without a car is to train which takes 3h 12m and costs €50 - €160.
It takes approximately 3h 12m to get from Mendrisio to Florence, including transfers.
Mendrisio to Florence bus services, operated by Onebus, depart from Como station.
Mendrisio to Florence train services, operated by Swiss Federal Railways (SBB CFF FFS), depart from Mendrisio station.
The best way to get from Mendrisio to Florence is to train which takes 3h 12m and costs €50 - €160. Alternatively, you can bus, which costs and takes 5h 25m.
What companies run services between Mendrisio, Switzerland and Florence, Italy?
You can take a train from Mendrisio to Firenze S.M.N. via Milano Centrale in around 3h 12m. Alternatively, Onebus operates a bus from Como to Florence Villa Constanza Bus Station once a week, and the journey takes 3h 7m.
- Website
- ita-airways.com
Flights from Milano Malpensa Airport to Florence Peretola Airport via Zurich
- Ave. Duration
- 3h 55m
- When
- Every day
- Estimated price
- €95–320
Flights from Milano Malpensa Airport to Florence Peretola Airport via Munich
- Ave. Duration
- 3h 52m
- When
- Monday, Wednesday, Friday, Saturday, Sunday, and Tuesday
- Estimated price
- €150–700
Flights from Milano Malpensa Airport to Florence Peretola Airport via Rome
- Ave. Duration
- 3h 40m
- When
- Monday and Saturday
- Estimated price
- €130–490
Flights from Milan Linate Airport to Florence Peretola Airport via Rome
- Ave. Duration
- 3h 27m
- When
- Every day
- Estimated price
- €140–250
Flights from Milan Linate Airport to Florence Peretola Airport via Vienna
- Ave. Duration
- 3h 40m
- When
- Every day
- Estimated price
- €110–400
Flights from Milan Linate Airport to Florence Peretola Airport via Frankfurt
- Ave. Duration
- 4h 10m
- When
- Tuesday, Friday, Saturday, and Sunday
- Estimated price
- €230–1,100
Flights from Milan Linate Airport to Florence Peretola Airport via Munich
- Ave. Duration
- 5h 10m
- When
- Monday, Wednesday, Thursday, and Friday
- Estimated price
- €180–800
- Website
- swiss.com
Flights from Milano Malpensa Airport to Florence Peretola Airport via Zurich
- Ave. Duration
- 3h 55m
- When
- Every day
- Estimated price
- €95–320
Flights from Milano Malpensa Airport to Florence Peretola Airport via Rome
- Ave. Duration
- 3h 40m
- When
- Monday and Saturday
- Estimated price
- €130–490
- Website
- lufthansa.com
Flights from Milano Malpensa Airport to Florence Peretola Airport via Munich
- Ave. Duration
- 3h 52m
- When
- Monday, Wednesday, Friday, Saturday, Sunday, and Tuesday
- Estimated price
- €150–700
Flights from Milano Malpensa Airport to Florence Peretola Airport via Rome
- Ave. Duration
- 3h 40m
- When
- Saturday
- Estimated price
- €130–490
Flights from Milan Linate Airport to Florence Peretola Airport via Frankfurt
- Ave. Duration
- 4h 10m
- When
- Tuesday, Friday, Saturday, and Sunday
- Estimated price
- €230–1,100
Flights from Milan Linate Airport to Florence Peretola Airport via Munich
- Ave. Duration
- 5h 10m
- When
- Monday, Wednesday, Thursday, and Friday
- Estimated price
- €180–800
- Website
- austrian.com
Flights from Milano Malpensa Airport to Florence Peretola Airport via Rome
- Ave. Duration
- 3h 40m
- When
- Monday and Saturday
- Estimated price
- €130–490
Flights from Milan Linate Airport to Florence Peretola Airport via Rome
- Ave. Duration
- 3h 40m
- When
- Every day
- Estimated price
- €140–250
Flights from Milan Linate Airport to Florence Peretola Airport via Vienna
- Ave. Duration
- 3h 40m
- When
- Every day
- Estimated price
- €110–400
- Website
- airdolomiti.it
Flights from Milano Malpensa Airport to Florence Peretola Airport via Munich
- Ave. Duration
- 3h 52m
- When
- Monday, Wednesday, Friday, Saturday, Sunday, and Tuesday
- Estimated price
- €150–700
Flights from Milan Linate Airport to Florence Peretola Airport via Frankfurt
- Ave. Duration
- 4h 10m
- When
- Tuesday, Friday, Saturday, and Sunday
- Estimated price
- €230–1,100
- Website
- polarair.ru
Flights from Milan Linate Airport to Florence Peretola Airport via Elba Island
- Ave. Duration
- 2h 20m
- When
- Sunday
- Estimated price
- €45–550
- Website
- flexflight.dk
Flights from Milan Linate Airport to Florence Peretola Airport via Elba Island
- Ave. Duration
- 2h 20m
- When
- Sunday
- Estimated price
- €45–550
- Phone
- +41 848 446 688
- Website
- sbb.ch
Train from Mendrisio to Milano Centrale
- Ave. Duration
- 59 min
- Frequency
- Hourly
- Estimated price
- €21–65
- Website
- https://www.sbb.ch/en
Train from Mendrisio to Malpensa Aeroporto T1
- Ave. Duration
- 1h 8m
- Frequency
- Hourly
- Estimated price
- €21–65
- Website
- https://www.sbb.ch/en
Train from Mendrisio to Milano Centrale
- Ave. Duration
- 59 min
- Frequency
- Hourly
- Estimated price
- €21–65
- Website
- https://www.sbb.ch/en
- Phone
- +39 06 68475475
- Website
- trenitalia.com
Train from Milano Centrale to Firenze S.M.N.
- Ave. Duration
- 1h 54m
- Frequency
- Hourly
- Estimated price
- €45–90
- Schedules at
- trenitalia.com
- Phone
- +39 06 8937 1892
- Website
- italotreno.it
Train from Milano Centrale to Firenze S.M.N.
- Ave. Duration
- 2h 41m
- Frequency
- 4 times a day
- Estimated price
- €35–80
- Website
- https://www.italotreno.it/en
Train from Milano Centrale to Firenze Santa Maria Novella
- Ave. Duration
- 2h 25m
- Frequency
- Hourly
- Estimated price
- €35–80
- Website
- https://www.italotreno.it/en
- Phone
- +39 06 68475475
- Website
- trenitalia.com
Train from Milano Centrale to Firenze S.M.N.
- Ave. Duration
- 3h 42m
- Frequency
- 3 times a day
- Estimated price
- €30–70
- Website
- https://www.trenitalia.com/en.html
- Phone
- +39 02 7249 4494
- [email protected]
- Website
- trenord.it
Train from Mendrisio to Malpensa Aeroporto T1
- Ave. Duration
- 1h 8m
- Frequency
- Hourly
- Estimated price
- €5–7
- Website
- https://www.trenord.it/en/
Train from Mendrisio to Monza
- Ave. Duration
- 48 min
- Frequency
- Hourly
- Estimated price
- €4–6
- Website
- https://www.trenord.it/en/
- Phone
- +39 0362 185 0590
- [email protected]
- Website
- onebus.it
Bus from Como to Florence Villa Constanza Bus Station
- Ave. Duration
- 3h 7m
- Frequency
- Once a week
- Website
- https://onebus.it/
Want to know more about travelling around Italy
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More Questions & Answers
Mendrisio to Florence bus services, operated by Onebus, arrive at Florence Villa Constanza Bus Station.
Mendrisio to Florence train services, operated by Swiss Federal Railways (SBB CFF FFS), arrive at Milano Centrale station.
Yes, the driving distance between Mendrisio to Florence is 354 km. It takes approximately 3h 34m to drive from Mendrisio to Florence.
There are 8494+ hotels available in Florence.






















