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How to get fromMendrisio to Spoletoby train (Trenitalia), train, bus, car, or plane

Find Transport to Spoleto

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There are 9 ways to get from Mendrisio to Spoleto by train (Trenitalia), train, bus, car, or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train via Rome

    best
    1. Take the train from Mendrisio to Milano Centraletrain train
    2. Take the train from Milano Centrale to Roma Tiburtinatrain train
    3. Take the train from Roma Tiburtina to Spoletotrain train
    6h 43m
    €100–168

  2. Train, bus

    cheapest
    1. Take the train from Mendrisio to Milano Centraletrain train
    2. Take the bus from Milan to Perugia Train Station Bus Stopbus bus
    3. Take the train from Perugia to Spoletotrain train Re
    10h 18m
    €37–62

  3. Drive  565.6 km

    1. Drive from Mendrisio to Spoletocar car 565.6 km
    5h 45m
    €102–148

  4. Train to Milan Linate Airport, fly to Fiumicino International Airport, train

    1. Take the train from Mendrisio to Monzatrain train
    2. Fly from Milan Linate Airport (LIN) to Fiumicino International Airport (FCO)plane plane LIN - FCO
    3. Take the train from Roma Termini to Spoletotrain train
    6h 44m
    €77–224

  5. Train

    1. Take the train from Mendrisio to Milano Centraletrain train Re80
    2. Take the train from Milano Centrale to Spoletotrain train Ic
    8h 30m
    €77–144

  6. Bus

    1. Take the bus from Como to Florence Villa Constanza Bus Stationbus bus
    2. Take the bus from Florence Villa Constanza Bus Station to Folignobus bus 443 / ...
    11h 21m
    €85–124

  7. Train to Milan Linate Airport, fly to Raffaello Sanzio Airport, train

    1. Take the train from Mendrisio to Monzatrain train
    2. Fly from Milan Linate Airport (LIN) to Raffaello Sanzio Airport (AOI)plane plane LIN - AOI
    3. Take the train from Jesi to Spoletotrain train
    7h 36m
    €115–382

  8. Train, train to Turin Caselle Airport, fly to Fiumicino International Airport

    1. Take the train from Mendrisio to Milano Centraletrain train
    2. Take the train from Milano Centrale to Torino Porta di Susatrain train
    3. Fly from Turin Caselle Airport (TRN) to Fiumicino International Airport (FCO)plane plane TRN - FCO
    4. Take the train from Roma Termini to Spoletotrain train
    8h 15m
    €74–269

  9. Train, train to Genoa Cristoforo Colombo Airport, fly to Fiumicino International Airport

    1. Take the train from Mendrisio to Milano Centraletrain train
    2. Take the train from Milano Centrale to Genova P.Za Principetrain train
    3. Fly from Genoa Cristoforo Colombo Airport (GOA) to Fiumicino International Airport (FCO)plane plane GOA - FCO
    4. Take the train from Roma Termini to Spoletotrain train
    8h 49m
    €98–269

Mendrisio to Spoleto by train

Calendar109Weekly Trains
Duration6h 43mAverage Duration
Ticket€100Cheapest Price
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Comparing Your Travel Options

Map of how to get from Mendrisio to Spoleto.ExpandLaunch map view
  • Distance: 734.8 km
  • Duration: 6h 43m

What companies run services between Mendrisio, Switzerland and Spoleto, Italy?

You can take a train from Mendrisio to Spoleto via Milano Centrale and Roma Tiburtina in around 6h 43m. Alternatively, you can take a bus from Mendrisio, Autosilo to Spoleto P. Vittoria via Chiasso - Stazione, Como - Chiesa di San Zenone, Como, Florence Villa Constanza Bus Station, Foligno, and Foligno - V. Roma Farmacia Afam. in around 11h 21m.

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