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How to get fromMesa to Buffaloby plane, bus, train, bus (Greyhound), or car

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There are 6 ways to get from Mesa to Buffalo by plane, bus, train, bus (Greyhound), or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Buffalo Niagara International Airport

    best
    1. Fly from Phoenix (PHX) to Buffalo Niagara International Airport (BUF)plane plane PHX - BUF
    6h 53m
    $254–1,131

  2. Bus, train via Flagstaff

    1. Take the bus from Tempe to Flagstaff Train Stationbus bus
    2. Take the train from Flagstaff to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Buffalo Depew Stationtrain train
    2d 2h
    $747–1,632

  3. Bus

    1. Take the bus from Love's Chandler to 285 S East End Ave - Pomonabus bus
    2. Take the bus from Montclair Transcenter to St Louis Bus Stationbus bus
    3. Take the bus from St Louis Bus Station to Wilson & Ferrell Shell Station - Columbusbus bus
    4. Take the bus from N Wilson Rd & Ferrell Pl - Columbus to Buffalo, NYbus bus
    2d 19h
    $507–915

  4. Drive 2,174.6 mi

    1. Drive from Mesa to Buffalocar car 2,174.6 mi
    35h 39m
    $397–574

  5. Fly to Rochester, bus

    1. Fly from Phoenix (PHX) to Rochester (ROC)plane plane PHX - ROC
    2. Take the bus from Rochester Bus Stop to Buffalobus bus
    10h 13m
    $281–1,146

  6. Bus, train

    1. Take the bus from Tempe to Tucson Downtownbus bus
    2. Take the train from Tucson Amtrak Station to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Buffalo Depew Stationtrain train
    2d 20h
    $890–2,020

Mesa to Buffalo by tram, bus, and train

Calendar7Weekly Services
Duration2d 2hAverage Duration
Ticket$747Cheapest Price
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Questions & Answers

Map of how to get from Mesa to Buffalo.ExpandLaunch map view
  • Distance: 1,933.6 mi
  • Duration: 6h 53m

What companies run services between Mesa, AZ, USA and Buffalo, NY, USA?

Southwest Airlines, United Airlines, and two other airlines fly from Phoenix (PHX) to Buffalo Niagara International Airport (BUF) every 4 hours. Alternatively, you can take a vehicle from Mesa to Buffalo, NY via Love's Chandler, 285 S East End Ave - Pomona, East End Ave and Mission Blvd E, Montclair Transit Center, Montclair Transcenter, St Louis Bus Station, and N Wilson Rd & Ferrell Pl - Columbus in around 2d 19h.

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