There are 6 ways to get from Mesa to Buffalo by plane, bus, train, bus (Greyhound), or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly to Buffalo Niagara International Airport
best- Fly from Phoenix (PHX) to Buffalo Niagara International Airport (BUF)plane PHX - BUF
7h 13m$193–855Bus, train via Flagstaff
- Take the bus from Phoenix Sky Harbor Airport/44th Street Sky Train Station to Flagstaff Train Stationbus
- Take the train from Flagstaff to Chicago Union Stationtrain
- Take the train from Chicago Union Station to Buffalo Depew Stationtrain
2d 2h$614–1,487Bus
- Take the bus from Love's Chandler to 285 S East End Ave - Pomonabus
- Take the bus from Montclair Transcenter to St Louis Bus Stationbus
- Take the bus from St Louis Bus Station to Columbusbus
- Take the bus from Columbus - Mound St to Buffalo, NYbus
2d 20h$472–860Drive 2,174.6 mi
- Drive from Mesa to Buffalocar 2,174.6 mi
35h 39m$397–574Fly to Rochester, bus
- Fly from Phoenix (PHX) to Rochester (ROC)plane PHX - ROC
- Take the bus from Rochester Bus Stop to Buffalobus
10h 17m$280–1,144Bus, train
- Take the bus from Tempe to Tucson Downtownbus
- Take the train from Tucson Amtrak Station to Chicago Union Stationtrain
- Take the train from Chicago Union Station to Buffalo Depew Stationtrain
2d 21h$711–1,641
Mesa to Buffalo by tram, bus, and train
Questions & Answers
The cheapest way to get from Mesa to Buffalo is to fly which costs $190 - $900 and takes 7h 13m.
The fastest way to get from Mesa to Buffalo is to fly which takes 7h 13m and costs $190 - $900.
No, there is no direct bus from Mesa to Buffalo. However, there are services departing from Love's Chandler and arriving at Buffalo, NY via East End Ave and Mission Blvd E, Montclair Transcenter, St Louis Bus Station and Columbus - Mound St. The journey, including transfers, takes approximately 2 days 20h.
The distance between Mesa and Buffalo is 1941 miles. The road distance is 2187.3 miles.
The best way to get from Mesa to Buffalo without a car is to bus and train via Flagstaff which takes 2 days 2h and costs $600 - $1,500.
It takes approximately 7h 13m to get from Mesa to Buffalo, including transfers.
Mesa to Buffalo bus services, operated by Tufesa, depart from Love's Chandler station.
The best way to get from Mesa to Buffalo is to fly which takes 7h 13m and costs $190 - $900. Alternatively, you can bus, which costs $470 - $900 and takes 2 days 20h.
Mesa to Buffalo bus services, operated by Tufesa, arrive at 285 S East End Ave - Pomona station.
Buffalo is 3h ahead of Mesa. It is currently 11:00 AM in Mesa and 2:00 PM in Buffalo.
What companies run services between Mesa, AZ, USA and Buffalo, NY, USA?
Southwest Airlines, United Airlines, and Delta fly from Phoenix (PHX) to Buffalo Niagara International Airport (BUF) every 4 hours. Alternatively, you can take a vehicle from Mesa to Buffalo, NY via Love's Chandler, 285 S East End Ave - Pomona, East End Ave and Mission Blvd E, Montclair Transit Center, Montclair Transcenter, St Louis Bus Station, and Columbus - Mound St in around 2d 20h.
- Website
- southwest.com
Flights from Phoenix to Buffalo Niagara International Airport
- Ave. Duration
- 4h 10m
- When
- Saturday
- Estimated price
- $190–850
Flights from Phoenix to Buffalo Niagara International Airport via Chicago Midway
- Ave. Duration
- 6h 2m
- When
- Every day
- Estimated price
- $190–850
Flights from Phoenix to Buffalo Niagara International Airport via Denver
- Ave. Duration
- 6h 3m
- When
- Sunday, Tuesday, Wednesday, and Saturday
- Estimated price
- $200–850
Flights from Phoenix to Buffalo Niagara International Airport via Nashville
- Ave. Duration
- 6h 10m
- When
- Tuesday and Wednesday
- Estimated price
- $210–900
Flights from Phoenix to Rochester via Chicago Midway
- Ave. Duration
- 6h 33m
- When
- Every day
- Estimated price
- $250–1,100
Flights from Phoenix to Rochester via Baltimore
- Ave. Duration
- 8h 27m
- When
- Every day
- Estimated price
- $280–1,200
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Flagstaff to Chicago Union Station
- Ave. Duration
- 32h 43m
- Frequency
- Once daily
- Estimated price
- $450–1,000
- Website
- Amtrak
Train from Chicago Union Station to Buffalo Depew Station
- Ave. Duration
- 10h 23m
- Frequency
- Twice daily
- Estimated price
- $140–310
- Website
- Amtrak
Train from Tucson Amtrak Station to Chicago Union Station
- Ave. Duration
- 2d 3h
- Frequency
- 3 times a week
- Estimated price
- $550–1,300
- Website
- Amtrak
Train from Chicago Union Station to Buffalo Depew Station
- Ave. Duration
- 10h 23m
- Frequency
- Twice daily
- Estimated price
- $140–310
- Website
- Amtrak
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Phoenix Sky Harbor Airport/44th Street Sky Train Station to Flagstaff Train Station
- Ave. Duration
- 2h 25m
- Frequency
- Once daily
- Estimated price
- $20–35
- Schedules at
- Flixbus USA
Bus from Rochester Bus Stop to Buffalo
- Ave. Duration
- 1h 30m
- Frequency
- 5 times a day
- Estimated price
- $10–17
- Schedules at
- Flixbus USA
Bus from Tempe to Tucson Downtown
- Ave. Duration
- 1h 45m
- Frequency
- 5 times a day
- Estimated price
- $15–25
- Schedules at
- Flixbus USA
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More Questions & Answers
Yes, the driving distance between Mesa to Buffalo is 2187 miles. It takes approximately 35h 39m to drive from Mesa to Buffalo.
There are 266+ hotels available in Buffalo.







