There are 5 ways to get from Mesa to Des Moines by plane, bus, train, bus (Greyhound), or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly from Phoenix
best- Fly from Phoenix (PHX) to Des Moines (DSM)plane PHX - DSM
4h 45m$199–623Fly from Phoenix-Mesa Gateway Airport
cheapest- Fly from Phoenix-Mesa Gateway Airport (AZA) to Des Moines (DSM)plane AZA - DSM
5h 4m$181–775Bus, train
- Take the bus from Phoenix Sky Harbor Airport/44th Street Sky Train Station to Flagstaff Train Stationbus
- Take the train from Flagstaff to Kansas Citytrain
- Take the bus from Kansas City Bus Station to Des Moinesbus
34h 30m$389–892Bus
- Take the bus from Phoenix Bus Station to Tulsa Bus Stationbus Greyhound US1210
- Take the bus from Tulsa to Des Moinesbus Jefferson Lines 802
34h 43m$262–452Drive 1,376.6 mi
- Drive from Mesa to Des Moinescar 1,376.6 mi
24h 12m$252–363
Mesa to Des Moines by tram, bus, train, and foot
Questions & Answers
The cheapest way to get from Mesa to Des Moines is to drive which costs $250 - $370 and takes 24h 12m.
The fastest way to get from Mesa to Des Moines is to fly which takes 4h 45m and costs $190 - $650.
No, there is no direct bus from Mesa to Des Moines. However, there are services departing from University Dr & Mesa Dr and arriving at Des Moines via 24th St/Baseline PNR, Phoenix Bus Station and Tulsa. The journey, including transfers, takes approximately 34h 43m.
The distance between Mesa and Des Moines is 1173 miles. The road distance is 1384.7 miles.
The best way to get from Mesa to Des Moines without a car is to bus and train which takes 34h 30m and costs $380 - $900.
It takes approximately 4h 45m to get from Mesa to Des Moines, including transfers.
Mesa to Des Moines bus services, operated by Greyhound USA, depart from Phoenix Bus Station.
The best way to get from Mesa to Des Moines is to fly which takes 4h 45m and costs $190 - $650. Alternatively, you can bus, which costs $260 - $460 and takes 34h 43m.
Mesa to Des Moines bus services, operated by Greyhound USA, arrive at Tulsa Bus Station.
Des Moines is 2h ahead of Mesa. It is currently 12:05 PM in Mesa and 2:05 PM in Des Moines.
What companies run services between Mesa, AZ, USA and Des Moines, IA, USA?
American Airlines, Southwest Airlines, and two other airlines fly from Phoenix (PHX) to Des Moines (DSM) every 4 hours. Alternatively, you can take a bus from University Dr & Mesa Dr to Des Moines via 24th St/Baseline PNR, 24th St & Buckeye Rd, Phoenix Bus Station, and Tulsa in around 34h 43m.
- Website
- southwest.com
Flights from Phoenix to Des Moines
- Ave. Duration
- 2h 45m
- When
- Sunday
- Estimated price
- $140–700
Flights from Phoenix to Des Moines via Denver
- Ave. Duration
- 5h 1m
- When
- Monday, Thursday, Friday, Sunday, and Saturday
- Estimated price
- $150–700
Flights from Phoenix to Des Moines via Las Vegas
- Ave. Duration
- 5h
- When
- Sunday, Monday, Thursday, and Friday
- Estimated price
- $170–750
- Website
- united.com
Flights from Phoenix to Des Moines via Denver
- Ave. Duration
- 4h 46m
- When
- Every day
- Estimated price
- $150–700
- Website
- allegiantair.com
Flights from Phoenix-Mesa Gateway Airport to Des Moines
- Ave. Duration
- 2h 42m
- When
- Friday, Wednesday, Saturday, and Monday
- Estimated price
- $160–750
- Website
- flyfrontier.com
Flights from Phoenix to Des Moines via Denver
- Ave. Duration
- 5h 16m
- When
- Monday and Friday
- Estimated price
- $180–600
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Flagstaff to Kansas City
- Ave. Duration
- 24h 27m
- Frequency
- Once daily
- Estimated price
- $340–800
- Website
- Amtrak
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Phoenix Sky Harbor Airport/44th Street Sky Train Station to Flagstaff Train Station
- Ave. Duration
- 2h 25m
- Frequency
- Once daily
- Estimated price
- $20–35
- Schedules at
- Flixbus USA
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Kansas City Bus Station to Des Moines
- Ave. Duration
- 3h 10m
- Frequency
- Once daily
- Estimated price
- $27–55
- Website
- Greyhound
Bus from Phoenix Bus Station to Tulsa Bus Station
- Ave. Duration
- 22h 45m
- Frequency
- Twice daily
- Estimated price
- $160–300
- Website
- Greyhound
- Phone
- +1-858-800-8898
- Website
- jeffersonlines.com
Bus from Tulsa to Des Moines
- Ave. Duration
- 8h 25m
- Frequency
- Once daily
- Estimated price
- $100–150
- Book at
- Jefferson Lines
- Adult
- $100–150
Want to know more about travelling around United States
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More Questions & Answers
Yes, the driving distance between Mesa to Des Moines is 1385 miles. It takes approximately 24h 12m to drive from Mesa to Des Moines.
Book your Mesa to Des Moines bus tickets online with Omio.
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