There are 5 ways to get from Mesa to Guaymas by plane, bus, or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly to Hermosillo International Airport, bus
best- Fly from Phoenix (PHX) to Hermosillo International Airport (HMO)plane PHX - HMO
- Take the bus from Hermosillo to Guaymasbus
6h 46m$3,547–10,497Bus
cheapest- Take the bus from Phoenix to Guaymasbus San José
11h 58m$1,061–1,511Drive 692.4 km
- Drive from Mesa to Guaymascar 692.4 km
7h 27m$1,453–2,098Fly to Ciudad Obregón International Airport, bus
- Fly from Phoenix (PHX) to Ciudad Obregón International Airport (CEN)plane PHX - CEN
- Take the bus from Ciudad Obregón to Guaymasbus
16h 6m$3,177–10,857Bus via Hermosillo
- Take the bus from Phoenix Bus Station to Hermosillobus
- Take the bus from Hermosillo to Guaymasbus Plus / ...
12h 52m$1,064–2,024
Mesa to Guaymas by tram and bus
Comparing Your Travel Options
The cheapest way to get from Mesa to Guaymas is to bus which costs $1000 - $1600 and takes 11h 58m.
The fastest way to get from Mesa to Guaymas is to fly and bus which takes 6h 46m and costs $3500 - $11000.
No, there is no direct bus from Mesa to Guaymas. However, there are services departing from McDowell Rd & Central Av and arriving at Guaymas via Phoenix. The journey, including transfers, takes approximately 11h 58m.
The distance between Mesa and Guaymas is 660 km. The road distance is 692.4 km.
The best way to get from Mesa to Guaymas without a car is to bus which takes 11h 58m and costs $1000 - $1600.
It takes approximately 6h 46m to get from Mesa to Guaymas, including transfers.
Mesa to Guaymas bus services, operated by Tufesa Mexico, depart from Phoenix station.
Mesa to Guaymas bus services, operated by Tufesa Mexico, arrive at Guaymas station.
Yes, the driving distance between Mesa to Guaymas is 692 km. It takes approximately 7h 27m to drive from Mesa to Guaymas.
There are 141+ hotels available in Guaymas.
What companies run services between Mesa, AZ, USA and Guaymas, Mexico?
Tufesa Mexico operates a bus from Phoenix to Guaymas every 4 hours. Tickets cost $950–1,400 and the journey takes 9h 20m.
- Website
- volaris.com
Flights from Phoenix to Ciudad Obregón International Airport via Guadalajara
- Ave. Duration
- 16h 17m
- When
- Every day
- Estimated price
- $3,400–11,000
Flights from Phoenix to Ciudad Obregón International Airport via Culiacan, Guadalajara
- Ave. Duration
- 19h 19m
- When
- Thursday and Sunday
- Estimated price
- $3,400–11,000
Flights from Phoenix to Ciudad Obregón International Airport via Hermosillo International Airport, Tijuana
- Ave. Duration
- 10h 25m
- When
- Every day
- Estimated price
- $2,900–10,000
- Website
- aa.com
Flights from Phoenix to Hermosillo International Airport
- Ave. Duration
- 1h 28m
- When
- Every day
- Estimated price
- $900–6,000
- Website
- aeromexico.com
Flights from Phoenix to Ciudad Obregón International Airport via Mexico City
- Ave. Duration
- 19h 18m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $2,600–11,000
- Phone
- +52 644 410 2444
- [email protected]
- Website
- tufesa.com.mx
Bus from Hermosillo to Guaymas
- Ave. Duration
- 1h 51m
- Frequency
- Every 3 hours
- Estimated price
- $180–420
- Schedules at
- tufesa.com.mx
- Book at
- tufesa.com.mx
- Plus
- $180–420
- Titanium
- $200–420
Bus from Phoenix to Guaymas
- Ave. Duration
- 9h 20m
- Frequency
- Every 4 hours
- Estimated price
- $950–1,400
- Schedules at
- tufesa.com.mx
- Book at
- tufesa.com.mx
- Plus
- $950–1,400
- Titanium
- $1,000–1,300
Bus from Ciudad Obregón to Guaymas
- Ave. Duration
- 2h
- Frequency
- 3 times a day
- Estimated price
- $170–410
- Schedules at
- tufesa.com.mx
- Book at
- tufesa.com.mx
- Plus
- $170–410
- Titanium
- $180–400
Bus from Hermosillo to Guaymas
- Ave. Duration
- 1h 51m
- Frequency
- Every 3 hours
- Estimated price
- $180–420
- Schedules at
- tufesa.com.mx
- Book at
- tufesa.com.mx
- Plus
- $180–420
- Titanium
- $200–420
- Phone
- +52 55 5141 4300
- [email protected]
- Website
- odm.com.mx
Bus from Hermosillo to Guaymas
- Ave. Duration
- 2h
- Frequency
- Every 2 hours
- Estimated price
- $260–750
- Schedules at
- odm.com.mx
- Book at
- odm.com.mx
Bus from Ciudad Obregón to Guaymas
- Ave. Duration
- 2h
- Frequency
- 5 times a day
- Estimated price
- $260–700
- Schedules at
- odm.com.mx
- Book at
- odm.com.mx
Bus from Hermosillo to Guaymas
- Ave. Duration
- 2h
- Frequency
- Every 2 hours
- Estimated price
- $260–750
- Schedules at
- odm.com.mx
- Book at
- odm.com.mx
- Phone
- +52 800 624 6618
- [email protected]
- Website
- albatrosautobuses.mx
Bus from Hermosillo to Guaymas
- Ave. Duration
- 2h
- Frequency
- 3 times a day
- Estimated price
- $140–210
- Schedules at
- albatrosautobuses.mx
- Book at
- albatrosautobuses.mx
Bus from Ciudad Obregón to Guaymas
- Ave. Duration
- 2h
- Frequency
- Once daily
- Estimated price
- $140–210
- Schedules at
- albatrosautobuses.mx
- Book at
- albatrosautobuses.mx
Bus from Hermosillo to Guaymas
- Ave. Duration
- 2h
- Frequency
- 3 times a day
- Estimated price
- $140–210
- Schedules at
- albatrosautobuses.mx
- Book at
- albatrosautobuses.mx
- Phone
- +52 55 4440 3187
- [email protected]
- Website
- futura.com.mx
Bus from Hermosillo to Guaymas
- Ave. Duration
- 2h 9m
- Frequency
- Twice daily
- Estimated price
- $410–600
- Schedules at
- futura.com.mx
- Book at
- futura.com.mx
Bus from Ciudad Obregón to Guaymas
- Ave. Duration
- 2h
- Frequency
- Twice daily
- Estimated price
- $240–550
- Schedules at
- futura.com.mx
- Book at
- futura.com.mx
Bus from Hermosillo to Guaymas
- Ave. Duration
- 2h 9m
- Frequency
- Twice daily
- Estimated price
- $410–600
- Schedules at
- futura.com.mx
- Book at
- futura.com.mx
- Phone
- +52 55 4440 3187
- [email protected]
- Website
- autobuseselite.com.mx
Bus from Hermosillo to Guaymas
- Ave. Duration
- 2h 40m
- Frequency
- Once daily
- Estimated price
- $390–600
- Schedules at
- autobuseselite.com.mx
- Book at
- autobuseselite.com.mx
Bus from Ciudad Obregón to Guaymas
- Ave. Duration
- 2h
- Frequency
- 3 times a day
- Estimated price
- $270–550
- Schedules at
- autobuseselite.com.mx
- Book at
- autobuseselite.com.mx
Bus from Hermosillo to Guaymas
- Ave. Duration
- 2h 40m
- Frequency
- Once daily
- Estimated price
- $390–600
- Schedules at
- autobuseselite.com.mx
- Book at
- autobuseselite.com.mx
- Phone
- +52 55 4440 3187
- [email protected]
- Website
- autobusesaguacaliente.mx
Bus from Ciudad Obregón to Guaymas
- Ave. Duration
- 1h 45m
- Frequency
- 4 times a day
- Estimated price
- $150–250
- Schedules at
- autobusesaguacaliente.mx
- Book at
- autobusesaguacaliente.mx
- Phone
- +52 55 4440 3187
- [email protected]
- Website
- chihuahuenses.com.mx
Bus from Ciudad Obregón to Guaymas
- Ave. Duration
- 1h 45m
- Frequency
- 3 times a day
- Estimated price
- $260–550
- Schedules at
- chihuahuenses.com.mx
- Book at
- chihuahuenses.com.mx
- Phone
- +52 664 299 0487
- [email protected]
- Website
- acnautobuses.com
Bus from Phoenix Bus Station to Hermosillo
- Ave. Duration
- 8h 30m
- Frequency
- Once daily
- Estimated price
- $850–1,200
- Schedules at
- acnautobuses.com
- Book at
- acnautobuses.com
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