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How to get fromMesa to Indianapolisby plane, bus (Greyhound), bus, train, or car

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There are 5 ways to get from Mesa to Indianapolis by plane, bus (Greyhound), bus, train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly

    best
    1. Fly from Phoenix (PHX) to Indianapolis (IND)plane plane PHX - IND
    6h 15m
    $184–804

  2. Bus (Greyhound)

    1. Take the bus from Phoenix Bus Station to St Louis Bus Stationbus bus Greyhound US1210
    2. Take the bus from St Louis Bus Station to Indianapolis Union Stationbus bus Greyhound US0421
    37h 46m
    $267–512

  3. Bus, train via Flagstaff

    1. Take the bus from Tempe to Flagstaff Train Stationbus bus
    2. Take the train from Flagstaff to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Indianapolistrain train
    43h 49m
    $635–1,272

  4. Drive 1,679.4 mi

    1. Drive from Mesa to Indianapoliscar car 1,679.4 mi
    27h 5m
    $307–443

  5. Bus, train

    1. Take the bus from Tempe to Tucson Downtownbus bus
    2. Take the train from Tucson Amtrak Station to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Indianapolistrain train
    2d 14h
    $778–1,660

Mesa to Indianapolis by tram and bus (Greyhound)

Calendar14Weekly Services
Duration37h 46mAverage Duration
Ticket$267Cheapest Price
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Questions & Answers

Map of how to get from Mesa to Indianapolis.ExpandLaunch map view
  • Distance: 1,511.8 mi
  • Duration: 6h 15m

What companies run services between Mesa, AZ, USA and Indianapolis, IN, USA?

American Airlines, Southwest Airlines, and United Airlines fly from Phoenix (PHX) to Indianapolis (IND) every 4 hours. Alternatively, you can take a vehicle from Mesa Dr/Main St to Indianapolis Union Station via 44th St/Washington, Phoenix Sky Harbor Airport/44th Street Sky Train Station, 24th St Station, Phoenix Bus Station, and St Louis Bus Station in around 37h 46m.

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