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How to get fromMesa to Mayo Clinicby plane, bus (Greyhound), bus, train, or car

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There are 8 ways to get from Mesa to Mayo Clinic by plane, bus (Greyhound), bus, train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Rochester

    best
    1. Fly from Phoenix (PHX) to Rochester (RST)plane plane PHX - RST
    8h
    $93–462

  2. Bus

    1. Take the bus from Phoenix Bus Station to Tulsa Bus Stationbus bus
    2. Take the bus from Tulsa to St. Paulbus bus
    3. Take the bus from Minneapolis / St Paul Airport to Groome Transportation Office - Rochesterbus bus
    43h 31m
    $404–585

  3. Bus, train via Milwaukee

    1. Take the bus from Phoenix Sky Harbor Airport/44th Street Sky Train Station to Flagstaff Train Stationbus bus
    2. Take the train from Flagstaff to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Milwaukeetrain train
    4. Take the bus from Milwaukee to Rochesterbus bus
    47h 4m
    $1,040–1,712

  4. Drive  1,583.7 mi

    1. Drive from Mesa to Mayo Cliniccar car 1,583.7 mi
    27h 39m
    $271–391

  5. Fly to Minneapolis–Saint Paul International Airport, bus

    1. Fly from Phoenix (PHX) to Minneapolis–Saint Paul International Airport (MSP)plane plane PHX - MSP
    2. Take the bus from Minneapolis / St Paul Airport to Groome Transportation Office - Rochesterbus bus
    7h 55m
    $202–482

  6. Fly to The Eastern Iowa Airport, drive

    1. Fly from Phoenix (PHX) to The Eastern Iowa Airport (CID)plane plane PHX - CID
    2. Drive from Cedar-Rapids-Airport-CID to Mayo Cliniccar car
    8h 19m
    $116–457

  7. Bus, train

    1. Take the bus from Phoenix Sky Harbor Airport/44th Street Sky Train Station to Flagstaff Train Stationbus bus
    2. Take the train from Flagstaff to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to St. Paul-Minneapolistrain train
    4. Take the bus from St. Paul to Rochesterbus bus
    2d
    $1,173–1,927

  8. Bus, train #2

    1. Take the bus from Tempe to Tucson Downtownbus bus
    2. Take the train from Tucson Amtrak Station to Chicago Union Stationtrain train
    3. Take the bus from W Jackson Blvd, after S Clinton St to 250 N. Lake St - Madison UW Campusbus bus
    4. Take the bus from Madison to Rochesterbus bus
    2d 17h
    $1,294–2,058

Mesa to Mayo Clinic by tram, bus, train, and foot

Calendar7Weekly Services
Duration47h 4mAverage Duration
Ticket$1,040Cheapest Price
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Comparing Your Travel Options

Map of how to get from Mesa to Mayo Clinic.ExpandLaunch map view
  • Distance: 1,293.6 mi
  • Duration: 8h

What companies run services between Mesa, AZ, USA and Mayo Clinic, MN, USA?

Delta, American Airlines, and Sun Country Airlines fly from Phoenix (PHX) to Rochester (RST) every 4 hours. Alternatively, you can take a vehicle from Mesa Dr/Main St to Mayo Clinic via 44th St/Washington, Phoenix Sky Harbor Airport/44th Street Sky Train Station, 24th St Station, Phoenix Bus Station, Tulsa, St. Paul, Union Depot & Gate A1, MSP Terminal 1 Transit Station, Minneapolis / St Paul Airport, and Groome Transportation Office - Rochester in around 43h 31m.

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