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How to get fromMesa to Panama City Beachby plane, bus (Greyhound), bus, train, or car

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There are 7 ways to get from Mesa to Panama City Beach by plane, bus (Greyhound), bus, train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Northwest Florida Beaches International Airport

    best
    1. Fly from Phoenix (PHX) to Northwest Florida Beaches International Airport (ECP)plane plane PHX - ECP
    7h 22m
    $172–617

  2. Fly to Pensacola International Airport, bus

    cheapest
    1. Fly from Phoenix (PHX) to Pensacola International Airport (PNS)plane plane PHX - PNS
    2. Take the bus from Pensacola Airport to Panama City Beach Bus Stationbus bus
    10h 18m
    $126–503

  3. Bus

    1. Take the bus from Phoenix to El Pasobus bus Cbx
    2. Take the bus from El Paso Bus Station to Houston Bus Stationbus bus
    3. Take the bus from Houston Bus Station to Panama City Beach Bus Stationbus bus
    38h 41m
    $280–513

  4. Bus, train

    1. Take the bus from Tempe to Tucson Downtownbus bus
    2. Take the train from Tucson Amtrak Station to New Orleans Union Passenger Terminaltrain train
    3. Take the bus from New Orleans Bus Station to Mobile Bus Stationbus bus
    4. Take the bus from Mobile Bus Station to Panama City Beach Bus Stationbus bus
    47h 58m
    $553–1,139

  5. Drive 1,737.7 mi

    1. Drive from Mesa to Panama City Beachcar car 1,737.7 mi
    28h 53m
    $318–459

  6. Fly to Destin–Fort Walton Beach Airport, drive

    1. Fly from Phoenix (PHX) to Destin–Fort Walton Beach Airport (VPS)plane plane PHX - VPS
    2. Drive from Destin–Fort Walton Beach Airport (VPS) to Panama City Beachcar car
    8h 36m
    $132–568

  7. Fly to Dothan Regional Airport, drive

    1. Fly from Phoenix (PHX) to Dothan Regional Airport (DHN)plane plane PHX - DHN
    2. Drive from Dothan Regional Airport (DHN) to Panama City Beachcar car
    11h 18m
    $159–478

Phoenix (PHX) to Northwest Florida Beaches International Airport (ECP) flights

Calendar59Weekly Planes
Duration6h 9mAverage Duration
Ticket$125Cheapest Price
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Questions & Answers

Map of how to get from Mesa to Panama City Beach.ExpandLaunch map view
  • Distance: 1,578.4 mi
  • Duration: 7h 22m

What companies run services between Mesa, AZ, USA and Panama City Beach, FL, USA?

Southwest Airlines, United Airlines, and American Airlines fly from Phoenix (PHX) to Northwest Florida Beaches International Airport (ECP) every 4 hours. Alternatively, you can take a bus from University Dr & Mesa Dr to Panama City Beach via University Dr & Rural Rd, University Dr/Rural Rd, Priest Dr/Washington St, Washington St & Priest Dr, Washington St & 25th St, Phoenix, El Paso, El Paso Bus Station, Houston Bus Station, and Panama City Beach Bus Station in around 38h 41m.

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