There are 4 ways to get from Mesa to San Diego by tram, plane, bus (Greyhound), car, or bus
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Tram, fly
best- Take the tram from Center/Main St to 44th St/Washingtontram
- Fly from Phoenix (PHX) to San Diego International Airport (SAN)plane PHX - SAN
2h 58m$102–332Bus (Greyhound)
cheapest- Take the bus from Phoenix Bus Station to El Cajon Transit Centerbus Greyhound US0851S
10h 5m$54–127Drive 361.3 mi
- Drive from Mesa to San Diegocar 361.3 mi
6h 10m$66–96Bus via Cross Border Express, San Diego
- Take the bus from Phoenix to Cross Border Express, San Diegobus El Paso
17h 27m$102–179
Mesa to San Diego by tram and bus (Greyhound)
Questions & Answers
The cheapest way to get from Mesa to San Diego is to drive which costs $65 - $95 and takes 6h 10m.
The fastest way to get from Mesa to San Diego is to tram and fly which takes 2h 58m and costs $100 - $340.
No, there is no direct bus from Mesa station to San Diego. However, there are services departing from Phoenix Bus Station and arriving at El Cajon Transit Center via . The journey, including transfers, takes approximately 10h 5m.
The distance between Mesa and San Diego is 319 miles. The road distance is 363.4 miles.
The best way to get from Mesa to San Diego without a car is to bus which takes 10h 5m and costs $50 - $130.
It takes approximately 2h 58m to get from Mesa to San Diego, including transfers.
Mesa to San Diego bus services, operated by Greyhound USA, depart from Phoenix Bus Station.
Mesa to San Diego bus services, operated by Greyhound USA, arrive at El Cajon Transit Center station.
Yes, the driving distance between Mesa to San Diego is 363 miles. It takes approximately 6h 10m to drive from Mesa to San Diego.
Book your Mesa to San Diego bus tickets online with Omio.
What companies run services between Mesa, AZ, USA and San Diego, CA, USA?
Greyhound USA operates a bus from Phoenix Bus Station to El Cajon Transit Center once daily. Tickets cost $50–110 and the journey takes 7h 15m.
- Website
- southwest.com
Flights from Phoenix to San Diego International Airport
- Ave. Duration
- 1h 12m
- When
- Every day
- Estimated price
- $45–310
- Website
- alaskaair.com
Flights from Phoenix to San Diego International Airport
- Ave. Duration
- 1h 29m
- When
- Every day
- Estimated price
- $160–240
- Website
- aa.com
Flights from Phoenix to San Diego International Airport
- Ave. Duration
- 1h 14m
- When
- Every day
- Estimated price
- $45–310
- Website
- flyfrontier.com
Flights from Phoenix to San Diego International Airport
- Ave. Duration
- 1h 11m
- When
- Every day
- Estimated price
- $90–330
- Phone
- +1 (602) 253-5000
- [email protected]
- Website
- valleymetro.org
Tram from Center/Main St to 44th St/Washington
- Ave. Duration
- 41 min
- Frequency
- Every 20 minutes
- Estimated price
- $2
- Website
- https://www.valleymetro.org
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- greyhound.com
Bus from Phoenix Bus Station to El Cajon Transit Center
- Ave. Duration
- 7h 15m
- Frequency
- Once daily
- Estimated price
- $50–110
- Website
- https://www.greyhound.com/
- [email protected]
- Website
- crossborderxpress.com
Bus from Phoenix to Cross Border Express, San Diego
- Ave. Duration
- 13h 35m
- Frequency
- Twice daily
- Estimated price
- $75–110
- Schedules at
- crossborderxpress.com
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