There are 7 ways to get from Mesa to Santa Cruz by plane, bus, bus (Amtrak), train, car, subway, or taxi
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly to Norman Y. Mineta San José International Airport, bus
best- Fly from Phoenix (PHX) to Norman Y. Mineta San José International Airport (SJC)plane PHX - SJC
- Take the bus from Diridon Station to Soquel Ave & Frontbus
5h 26m$198–266Bus
cheapest- Take the bus from Phoenix to Gilroybus
- Take the bus from Gilroy Transit Center to San Jose Diridonbus 68
- Take the bus from Diridon Station to Soquel Ave & Frontbus 17
21h 3m$121–166Bus, train
- Take the bus from Phoenix Bus Station to Los Angeles Union Stationbus
- Take the train from Los Angeles to San Josetrain
- Take the bus from Diridon Station to Soquel Ave & Frontbus 17
21h 6m$197–407Drive 722.7 mi
- Drive from Mesa to Santa Cruzcar 722.7 mi
12h 9m$132–191Fly to San Francisco International Airport, Caltrain, bus
- Fly from Phoenix (PHX) to San Francisco International Airport (SFO)plane PHX - SFO
- Take the train from Millbrae Caltrain Southbound to San Jose Diridon Caltrain Southboundtrain
- Take the bus from Diridon Station to Soquel Ave & Frontbus
6h 8m$167–938Fly to Oakland International Airport, BART, bus
- Fly from Phoenix (PHX) to Oakland International Airport (OAK)plane PHX - OAK
- Take the subway from Coliseum to Berryessa / North San Josesubway
- Take the bus from Diridon Station to Soquel Ave & Frontbus
6h 14m$342–484Taxi, train, bus
- Take the taxi from Mesa to Maricopa Amtraktaxi
- Take the train from Maricopa Amtrak to Los Angelestrain
- Take the train from Los Angeles to San Josetrain
- Take the bus from Diridon Station to Ocean & Waterbus 17
21h 15m$350–670
Mesa to Santa Cruz by tram, bus, and foot
Questions & Answers
The cheapest way to get from Mesa to Santa Cruz is to bus which costs $120 - $170 and takes 21h 3m.
The fastest way to get from Mesa to Santa Cruz is to fly and bus which takes 5h 26m and costs $190 - $270.
No, there is no direct bus from Mesa to Santa Cruz. However, there are services departing from McDowell Rd & Central Av and arriving at Soquel Ave & Front via Phoenix, Gilroy Transit Center and Diridon Station. The journey, including transfers, takes approximately 21h 3m.
The distance between Mesa and Santa Cruz is 675 miles. The road distance is 726.9 miles.
The best way to get from Mesa to Santa Cruz without a car is to bus which takes 21h 3m and costs $120 - $170.
It takes approximately 5h 26m to get from Mesa to Santa Cruz, including transfers.
Mesa to Santa Cruz bus services, operated by Tufesa, depart from Phoenix station.
Mesa to Santa Cruz bus services, operated by Tufesa, arrive at Gilroy station.
Yes, the driving distance between Mesa to Santa Cruz is 727 miles. It takes approximately 12h 9m to drive from Mesa to Santa Cruz.
There are 126+ hotels available in Santa Cruz.
What companies run services between Mesa, AZ, USA and Santa Cruz, CA, USA?
You can take a vehicle from Mesa Dr/Main St to Soquel Ave & Front via Downtown Phx Hub/Washington St, Downtown Phx Hub/Central Ave, McDowell/Central Ave, McDowell Rd & Central Av, McDowell Rd & 27th Av, Phoenix, Gilroy, Gilroy Transit Center, San Jose Diridon, and Diridon Station in around 21h 3m.
- Website
- southwest.com
Flights from Phoenix to Norman Y. Mineta San José International Airport
- Ave. Duration
- 1h 52m
- When
- Every day
- Estimated price
- $65–370
Flights from Phoenix to Norman Y. Mineta San José International Airport via Ontario/San Bernardino
- Ave. Duration
- 3h 12m
- When
- Tuesday, Wednesday, and Sunday
- Estimated price
- $70–380
Flights from Phoenix to Norman Y. Mineta San José International Airport via Burbank
- Ave. Duration
- 3h 25m
- When
- Tuesday, Wednesday, and Saturday
- Estimated price
- $70–380
Flights from Phoenix to Norman Y. Mineta San José International Airport via San Diego
- Ave. Duration
- 3h 30m
- When
- Tuesday to Friday
- Estimated price
- $75–390
Flights from Phoenix to Norman Y. Mineta San José International Airport via Las Vegas
- Ave. Duration
- 3h 31m
- When
- Monday, Thursday, Friday, and Sunday
- Estimated price
- $70–370
Flights from Phoenix to Norman Y. Mineta San José International Airport via Long Beach
- Ave. Duration
- 3h 35m
- When
- Tuesday and Wednesday
- Estimated price
- $70–380
Flights from Phoenix to Norman Y. Mineta San José International Airport via Santa Ana
- Ave. Duration
- 3h 35m
- When
- Tuesday and Wednesday
- Estimated price
- $70–380
Flights from Phoenix to San Francisco International Airport
- Ave. Duration
- 2h
- When
- Every day
- Estimated price
- $45–260
Flights from Phoenix to San Francisco International Airport via Las Vegas
- Ave. Duration
- 3h 43m
- When
- Monday, Thursday, Friday, Sunday, Tuesday, and Wednesday
- Estimated price
- $45–260
Flights from Phoenix to Oakland International Airport
- Ave. Duration
- 1h 56m
- When
- Every day
- Estimated price
- $70–390
Flights from Phoenix to Oakland International Airport via Ontario/San Bernardino
- Ave. Duration
- 3h 25m
- When
- Monday, Thursday, and Friday
- Estimated price
- $75–400
Flights from Phoenix to Oakland International Airport via Santa Ana
- Ave. Duration
- 3h 36m
- When
- Sunday, Monday, Thursday, and Friday
- Estimated price
- $75–400
Flights from Phoenix to Oakland International Airport via Las Vegas
- Ave. Duration
- 3h 40m
- When
- Sunday, Monday, Thursday, and Friday
- Estimated price
- $75–390
Flights from Phoenix to Oakland International Airport via Burbank
- Ave. Duration
- 3h 38m
- When
- Monday, Thursday, Friday, and Saturday
- Estimated price
- $75–400
Flights from Phoenix to Oakland International Airport via Long Beach
- Ave. Duration
- 3h 40m
- When
- Tuesday and Wednesday
- Estimated price
- $75–400
- Website
- aa.com
Flights from Phoenix to Norman Y. Mineta San José International Airport
- Ave. Duration
- 1h 50m
- When
- Every day
- Estimated price
- $65–370
Flights from Phoenix to San Francisco International Airport
- Ave. Duration
- 2h 2m
- When
- Every day
- Estimated price
- $45–260
- Website
- united.com
Flights from Phoenix to San Francisco International Airport
- Ave. Duration
- 2h 8m
- When
- Every day
- Estimated price
- $45–260
- Website
- flyfrontier.com
Flights from Phoenix to San Francisco International Airport
- Ave. Duration
- 2h 14m
- When
- Every day
- Estimated price
- $75–270
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Los Angeles to San Jose
- Ave. Duration
- 9h 55m
- Frequency
- Once daily
- Estimated price
- $130–280
- Website
- Amtrak
Train from Maricopa Amtrak to Los Angeles
- Ave. Duration
- 8h 33m
- Frequency
- 6 times a week
- Estimated price
- $130–280
- Website
- Amtrak
Train from Los Angeles to San Jose
- Ave. Duration
- 9h 55m
- Frequency
- Once daily
- Estimated price
- $130–280
- Website
- Amtrak
- Phone
- +1 800-660-4287
- Website
- Cal Train
Train from Millbrae Caltrain Southbound to San Jose Diridon Caltrain Southbound
- Ave. Duration
- 56 min
- Frequency
- Every 30 minutes
- Estimated price
- $7–10
- Website
- Cal Train
- Schedules at
- Cal Train
- One-way Adult
- $7–10
- Phone
- +1-510-464-6000
- Website
- BART
Subway from Coliseum to Berryessa / North San Jose
- Ave. Duration
- 46 min
- Frequency
- Every 15 minutes
- Estimated price
- $6–9
- Website
- BART
- Phone
- +1 (831) 425-8600
- Website
- Santa Cruz Metro
Bus from Diridon Station to Soquel Ave & Front
- Ave. Duration
- 48 min
- Frequency
- Every 30 minutes
- Estimated price
- $2–7
- Website
- Santa Cruz Metro
Bus from Diridon Station to Soquel Ave & Front
- Ave. Duration
- 48 min
- Frequency
- Every 30 minutes
- Estimated price
- $2–7
- Website
- Santa Cruz Metro
Bus from Diridon Station to Soquel Ave & Front
- Ave. Duration
- 48 min
- Frequency
- Every 30 minutes
- Estimated price
- $2–7
- Website
- Santa Cruz Metro
Bus from Diridon Station to Soquel Ave & Front
- Ave. Duration
- 48 min
- Frequency
- Every 30 minutes
- Estimated price
- $2–7
- Website
- Santa Cruz Metro
Bus from Diridon Station to Soquel Ave & Front
- Ave. Duration
- 48 min
- Frequency
- Every 30 minutes
- Estimated price
- $2–7
- Website
- Santa Cruz Metro
Bus from Diridon Station to Ocean & Water
- Ave. Duration
- 47 min
- Frequency
- Every 30 minutes
- Estimated price
- $2–7
- Website
- Santa Cruz Metro
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Bus from Diridon Station to Soquel Ave & Front
- Ave. Duration
- 51 min
- Frequency
- Every 4 hours
- Estimated price
- $10–15
- Website
- Amtrak
Bus from Gilroy Transit Center to San Jose Diridon
- Ave. Duration
- 45 min
- Frequency
- Twice daily
- Estimated price
- $10–15
- Website
- Amtrak
Bus from Diridon Station to Soquel Ave & Front
- Ave. Duration
- 51 min
- Frequency
- Every 4 hours
- Estimated price
- $10–15
- Website
- Amtrak
Bus from Diridon Station to Soquel Ave & Front
- Ave. Duration
- 51 min
- Frequency
- Every 4 hours
- Estimated price
- $10–15
- Website
- Amtrak
Bus from Diridon Station to Soquel Ave & Front
- Ave. Duration
- 51 min
- Frequency
- Every 4 hours
- Estimated price
- $10–15
- Website
- Amtrak
Bus from Diridon Station to Soquel Ave & Front
- Ave. Duration
- 51 min
- Frequency
- Every 4 hours
- Estimated price
- $10–15
- Website
- Amtrak
- Phone
- +1 833 766 3553
- Website
- Tufesa
Bus from Phoenix to Gilroy
- Ave. Duration
- 15h 20m
- Frequency
- Twice daily
- Estimated price
- $120–150
- Schedules at
- Tufesa
- Adult One way
- $120–150
- Phone
- +52 644 410 2444
- [email protected]
- Website
- tufesa.com.mx
Bus from Phoenix to Gilroy
- Ave. Duration
- 15h 20m
- Frequency
- Once daily
- Estimated price
- $95–130
- Schedules at
- tufesa.com.mx
- Book at
- tufesa.com.mx
- Plus
- $95–130
- Titanium
- $104–109
- Phone
- +1 408-321-2300
- Website
- Santa Clara VTA
Bus from Gilroy Transit Center to San Jose Diridon
- Ave. Duration
- 1h 44m
- Frequency
- Every 20 minutes
- Estimated price
- $2–5
- Website
- Santa Clara VTA
- Adult
- $2–5
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Phoenix Bus Station to Los Angeles Union Station
- Ave. Duration
- 7h 10m
- Frequency
- Every 3 hours
- Estimated price
- $55–110
- Website
- Greyhound
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Phoenix Bus Station to Los Angeles Union Station
- Ave. Duration
- 9h 15m
- Frequency
- Twice daily
- Estimated price
- $60–100
- Schedules at
- Flixbus USA
- Ave. Duration
- 44 min
- Estimated price
- $85–110
Mayflower Cab
- Phone
- +1 (602) 955-1355
VIP Taxi
- Phone
- +1 602-300-3000
- Website
- viptaxi.com
Yellow Cab AZ
- Phone
- +1 480-888-8888
- Website
- yellowcabaz.com
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