There are 9 ways to get from Mesa to Santa Maria by plane, bus, train, taxi, car, or bus (Flixbus)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly to San Luis Obispo County Regional Airport, bus
best- Fly from Phoenix (PHX) to San Luis Obispo County Regional Airport (SBP)plane PHX - SBP
- Take the bus from Government Center to Santa Maria Transit Centerbus
6h 40m$185–328Bus
cheapest- Take the bus from Phoenix Sky Harbor Airport/44th Street Sky Train Station to Los Angeles Union Stationbus
- Take the bus from Los Angeles Union Station to Santa Barbara Bus Stopbus
- Take the bus from Chapala at Figueroa to Santa Maria Transit Centerbus
19h 27m$96–160Bus, train via Phoenix, Bus Station (E Buckeye Rd)
- Take the bus from Phoenix Bus Station to Los Angeles Union Stationbus Greyhound US1000 / ...
- Take the train from Los Angeles to Guadalupe Amtrak Stationtrain Pacific Surfliner
16h 10m$118–244Taxi, train
- Take the taxi from Mesa to Maricopa Amtraktaxi
- Take the train from Maricopa Amtrak to Los Angelestrain
- Take the train from Los Angeles to Guadalupe Amtrak Stationtrain
16h 18m$269–515Drive 544.2 mi
- Drive from Mesa to Santa Mariacar 544.2 mi
9h 8m$100–144Fly to Santa Barbara Municipal Airport, bus
- Fly from Phoenix (PHX) to Santa Barbara Municipal Airport (SBA)plane PHX - SBA
- Take the bus from Santa Barbara Airport to Santa Maria Airport, CAbus
6h 50m$213–449Fly to Los Angeles International Airport, bus
- Fly from Phoenix (PHX) to Los Angeles International Airport (LAX)plane PHX - LAX
- Take the bus from Los Angeles Airport, CA to Santa Maria Airport, CAbus
9h 12m$188–364Bus, train
- Take the bus from Phoenix Sky Harbor Airport/44th Street Sky Train Station to Los Angeles Union Station Arrivalsbus FlixBus 2054
- Take the train from Los Angeles to Guadalupe Amtrak Stationtrain Pacific Surfliner
18h 19m$133–254Bus, train #2
- Take the bus from Phoenix to Santa Anabus El Paso
- Take the train from Santa Ana to Guadalupe Amtrak Stationtrain Pacific Surfliner
21h 57m$140–261
Mesa to Santa Maria by tram, bus, foot, and train
Questions & Answers
The cheapest way to get from Mesa to Santa Maria is to bus which costs $95 - $160 and takes 19h 27m.
The fastest way to get from Mesa to Santa Maria is to fly and bus which takes 6h 40m and costs $180 - $330.
No, there is no direct bus from Mesa to Santa Maria. However, there are services departing from University Dr & Mesa Dr and arriving at Santa Maria Transit Center via Tempe, Phoenix Sky Harbor Airport/44th Street Sky Train Station, Los Angeles Union Station, Cabrillo & Anacapa and Chapala at Figueroa. The journey, including transfers, takes approximately 19h 27m.
The distance between Mesa and Santa Maria is 564 miles. The road distance is 547.3 miles.
The best way to get from Mesa to Santa Maria without a car is to bus and train via Phoenix, Bus Station (E Buckeye Rd) which takes 16h 10m and costs $110 - $250.
It takes approximately 6h 40m to get from Mesa to Santa Maria, including transfers.
Mesa to Santa Maria bus services, operated by Flixbus USA, depart from Phoenix Sky Harbor Airport/44th Street Sky Train Station.
Mesa to Santa Maria bus services, operated by Flixbus USA, arrive at Los Angeles Union Station.
Yes, the driving distance between Mesa to Santa Maria is 547 miles. It takes approximately 9h 8m to drive from Mesa to Santa Maria.
There are 96+ hotels available in Santa Maria.
What companies run services between Mesa, AZ, USA and Santa Maria, Santa Barbara County, CA, USA?
You can take a bus from University Dr & Mesa Dr to Santa Maria Transit Center via University Dr & Rural Rd, Tempe, Phoenix Sky Harbor Airport/44th Street Sky Train Station, Los Angeles Union Station, Santa Barbara Bus Stop, Cabrillo & Anacapa, Chapala & Anapamu, and Chapala at Figueroa in around 19h 27m.
- Website
- southwest.com
Flights from Phoenix to Santa Barbara Municipal Airport via Las Vegas
- Ave. Duration
- 3h 40m
- When
- Sunday, Monday, Thursday, Friday, Tuesday, and Wednesday
- Estimated price
- $50–290
Flights from Phoenix to Santa Barbara Municipal Airport via San Diego
- Ave. Duration
- 3h 42m
- When
- Tuesday to Friday
- Estimated price
- $45–280
Flights from Phoenix to Los Angeles International Airport
- Ave. Duration
- 1h 25m
- When
- Every day
- Estimated price
- $35–230
- Website
- aa.com
Flights from Phoenix to San Luis Obispo County Regional Airport
- Ave. Duration
- 1h 41m
- When
- Every day
- Estimated price
- $40–250
Flights from Phoenix to San Luis Obispo County Regional Airport via San Diego
- Ave. Duration
- 3h 50m
- When
- Every day
- Estimated price
- $45–260
Flights from Phoenix to Santa Barbara Municipal Airport
- Ave. Duration
- 1h 33m
- When
- Every day
- Estimated price
- $45–280
Flights from Phoenix to Los Angeles International Airport
- Ave. Duration
- 1h 27m
- When
- Every day
- Estimated price
- $35–230
- Website
- united.com
Flights from Phoenix to San Luis Obispo County Regional Airport via Los Angeles International Airport
- Ave. Duration
- 4h 11m
- When
- Monday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $40–250
Flights from Phoenix to Santa Barbara Municipal Airport via Los Angeles International Airport
- Ave. Duration
- 3h 29m
- When
- Wednesday
- Estimated price
- $45–280
Flights from Phoenix to Los Angeles International Airport
- Ave. Duration
- 1h 37m
- When
- Every day
- Estimated price
- $35–230
- Website
- delta.com
Flights from Phoenix to Los Angeles International Airport
- Ave. Duration
- 1h 33m
- When
- Every day
- Estimated price
- $35–230
- Website
- alaskaair.com
Flights from Phoenix to San Luis Obispo County Regional Airport via San Diego
- Ave. Duration
- 4h 1m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $180–320
- Website
- flyfrontier.com
Flights from Phoenix to Los Angeles International Airport
- Ave. Duration
- 1h 34m
- When
- Every day
- Estimated price
- $95–170
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Los Angeles to Guadalupe Amtrak Station
- Ave. Duration
- 4h 38m
- Frequency
- 3 times a day
- Estimated price
- $60–130
- Website
- Amtrak
Train from Maricopa Amtrak to Los Angeles
- Ave. Duration
- 8h 33m
- Frequency
- 6 times a week
- Estimated price
- $120–280
- Website
- Amtrak
Train from Los Angeles to Guadalupe Amtrak Station
- Ave. Duration
- 4h 38m
- Frequency
- 3 times a day
- Estimated price
- $60–130
- Website
- Amtrak
Train from Los Angeles to Guadalupe Amtrak Station
- Ave. Duration
- 4h 38m
- Frequency
- 3 times a day
- Estimated price
- $60–130
- Website
- Amtrak
Train from Santa Ana to Guadalupe Amtrak Station
- Ave. Duration
- 5h 47m
- Frequency
- Twice daily
- Estimated price
- $70–160
- Website
- Amtrak
- Website
- SoCoTransit
Bus from Government Center to Santa Maria Transit Center
- Ave. Duration
- 1h 4m
- Frequency
- Every 2 hours
- Estimated price
- $2–4
- Website
- SoCoTransit
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Phoenix Bus Station to Los Angeles Union Station
- Ave. Duration
- 7h 10m
- Frequency
- 5 times a day
- Estimated price
- $55–110
- Website
- Greyhound
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Phoenix Bus Station to Los Angeles Union Station
- Ave. Duration
- 9h 15m
- Frequency
- 6 times a week
- Estimated price
- $55–95
- Schedules at
- Flixbus USA
Bus from Phoenix Sky Harbor Airport/44th Street Sky Train Station to Los Angeles Union Station Arrivals
- Ave. Duration
- 9h 34m
- Frequency
- 6 times a week
- Estimated price
- $70–120
- Schedules at
- Flixbus USA
Bus from Phoenix Sky Harbor Airport/44th Street Sky Train Station to Los Angeles Union Station
- Ave. Duration
- 9h 35m
- Frequency
- 6 times a week
- Estimated price
- $70–120
- Schedules at
- Flixbus USA
Bus from Los Angeles Union Station to Santa Barbara Bus Stop
- Ave. Duration
- 2h 10m
- Frequency
- 4 times a week
- Estimated price
- $15–26
- Schedules at
- Flixbus USA
- Phone
- +1 800-470-8818
- [email protected]
- Website
- Central Coast Shuttle
Bus from Santa Barbara Airport to Santa Maria Airport, CA
- Ave. Duration
- 1h 15m
- Frequency
- Every 4 hours
- Estimated price
- $60–75
- Website
- Central Coast Shuttle
- one way non-prepaid
- $65–75
- One-way prepaid 48 hours advance
- $60–70
Bus from Los Angeles Airport, CA to Santa Maria Airport, CA
- Ave. Duration
- 3h 45m
- Frequency
- Every 4 hours
- Estimated price
- $85–105
- Website
- Central Coast Shuttle
- one way non-prepaid
- $90–105
- One-way prepaid 48 hours advance
- $85–100
- Phone
- (805) 692-1902
- [email protected]
- Website
- Clean Air Express
Bus from Chapala at Figueroa to Santa Maria Transit Center
- Ave. Duration
- 1h 37m
- Frequency
- Once daily
- Estimated price
- $7–8
- Website
- Clean Air Express
- [email protected]
- Website
- CBX Cross Border Express
Bus from Phoenix to Santa Ana
- Ave. Duration
- 11h 40m
- Frequency
- Twice daily
- Estimated price
- $65–95
- Schedules at
- CBX Cross Border Express
- Ave. Duration
- 44 min
- Estimated price
- $85–110
Mayflower Cab
- Phone
- +1 (602) 955-1355
VIP Taxi
- Phone
- +1 602-300-3000
- Website
- viptaxi.com
Yellow Cab AZ
- Phone
- +1 480-888-8888
- Website
- yellowcabaz.com
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