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How to get fromMesa to Sioux Fallsby plane, bus, train, or car

Find Transport to Sioux Falls

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There are 5 ways to get from Mesa to Sioux Falls by plane, bus, train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Phoenix

    best
    1. Fly from Phoenix (PHX) to Sioux Falls (FSD)plane plane PHX - FSD
    6h 5m
    $124–424

  2. Fly from Phoenix-Mesa Gateway Airport

    cheapest
    1. Fly from Phoenix-Mesa Gateway Airport (AZA) to Sioux Falls (FSD)plane plane AZA - FSD
    6h 9m
    $106–466

  3. Bus

    1. Take the bus from Phoenix to Las Cruces, NMbus bus Cbx
    2. Take the bus from Las Cruces to Denverbus bus
    3. Take the bus from Denver to Omahabus bus
    4. Take the bus from Omaha to Sioux Fallsbus bus
    38h 28m
    $314–599

  4. Bus, train

    1. Take the bus from Phoenix Sky Harbor Airport/44th Street Sky Train Station to Flagstaff Train Stationbus bus
    2. Take the train from Flagstaff to Kansas Citytrain train
    3. Take the bus from Kansas City to Sioux Fallsbus bus
    40h 3m
    $534–1,049

  5. Drive 1,366.6 mi

    1. Drive from Mesa to Sioux Fallscar car 1,366.6 mi
    25h 5m
    $250–361

Phoenix (PHX) to Sioux Falls (FSD) flights

Calendar97Weekly Planes
Duration5h 28mAverage Duration
Ticket$97Cheapest Price
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Questions & Answers

Map of how to get from Mesa to Sioux Falls.ExpandLaunch map view
  • Distance: 1,098 mi
  • Duration: 6h 5m

What companies run services between Mesa, AZ, USA and Sioux Falls, SD, USA?

American Airlines, United Airlines, and two other airlines fly from Phoenix (PHX) to Sioux Falls (FSD) hourly. Alternatively, you can take a vehicle from Mesa Dr/Main St to The Bus Stop via 24th St/Washington, Phoenix, Las Cruces, Denver, Omaha, Sioux Falls, and Maple/Career NE corner in around 38h 28m.

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