There are 9 ways to get from Messina to Siena by ferry, train, bus, car, plane, or car ferry
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Ferry, train
best- Take the ferry from Messina Marittima to Villa S.Giovanniferry M1 / ...
- Take the train from Villa S.Giovanni to Firenze S.M.N.train Fr
- Take the train from Firenze S.M.N. to Sienatrain Re
10h 34mBus
cheapest- Take the bus from Messina to Sienabus N597 / ...
11h 30m€45–120Ferry, drive
- Take the ferry from Messina Marittima to Villa San Giovanniferry
- Drive from Villa San Giovanni to Sienacar
8h 46m€142–212Train to Catania–Fontanarossa Airport, fly to Florence Peretola Airport, train
- Take the train from Messina Centrale to Catania Centraletrain
- Fly from Catania–Fontanarossa Airport (CTA) to Florence Peretola Airport (FLR)plane CTA - FLR
- Take the train from Firenze S.M.N. to Sienatrain
7h 32m€48–216Car ferry, train
- Take the carferry from Messina Marittima to Villa San Giovannicarferry
- Take the train from Villa S.Giovanni to Chiusi-Chianciano T.train Ic
- Take the train from Chiusi-Chianciano T. to Sienatrain Re
13h 22m€91–273Bus via Florence
- Take the bus from Messina Main Train Station to Florence Villa Constanza Bus Stationbus Itabus
- Take the bus from Firenze Autostazione to Siena-Via Tozzibus 131R / ...
15h 42m€60–140Train to Catania–Fontanarossa Airport, fly to Pisa International Airport, train
- Take the train from Messina Centrale to Catania Centraletrain
- Fly from Catania–Fontanarossa Airport (CTA) to Pisa International Airport (PSA)plane CTA - PSA
- Take the train from Pisa Centrale to Empolitrain
- Take the train from Empoli to Sienatrain
7h 24m€64–244Train to Catania–Fontanarossa Airport, fly to Bologna Guglielmo Marconi Airport, train
- Take the train from Messina Centrale to Catania Centraletrain
- Fly from Catania–Fontanarossa Airport (CTA) to Bologna Guglielmo Marconi Airport (BLQ)plane CTA - BLQ
- Take the train from Bologna Centrale to Firenze S.M.N.train
- Take the train from Firenze S.M.N. to Sienatrain
8h 20m€49–236Train to Palermo Airport, fly to Pisa International Airport, train
- Take the train from Messina Centrale to Palermo Centraletrain
- Fly from Palermo Airport (PMO) to Pisa International Airport (PSA)plane PMO - PSA
- Take the train from Pisa Centrale to Empolitrain
- Take the train from Empoli to Sienatrain
9h 14m€80–306
Catania–Fontanarossa Airport (CTA) to Florence Peretola Airport (FLR) flights
Comparing Your Travel Options
The cheapest way to get from Messina to Siena is to bus which costs €45 - €120 and takes 11h 30m.
The fastest way to get from Messina to Siena is to train and fly which takes 7h 24m and costs €60 - €250.
Yes, there is a direct bus departing from Messina and arriving at Siena. Services depart twice daily, and operate every day. The journey takes approximately 11h 30m.
The distance between Messina and Siena is 993 km.
The best way to get from Messina to Siena without a car is to ferry and train which takes 10h 34m and costs .
It takes approximately 10h 34m to get from Messina to Siena, including transfers.
Messina to Siena bus services, operated by FlixBus, depart from Messina station.
Messina to Siena bus services, operated by FlixBus, arrive at Siena station.
Book your Messina to Siena bus tickets online with Omio and FlixBus.
There are 2381+ hotels available in Siena.
What companies run services between Messina, Italy and Siena, Italy?
FlixBus operates a bus from Messina to Siena once daily. Tickets cost €80–120 and the journey takes 11h 30m. Itabus S.p.A. also services this route once daily.
- Website
- ryanair.com
Flights from Catania–Fontanarossa Airport to Pisa International Airport
- Ave. Duration
- 1h 35m
- When
- Every day
- Estimated price
- €35–190
Flights from Catania–Fontanarossa Airport to Bologna Guglielmo Marconi Airport
- Ave. Duration
- 1h 40m
- When
- Every day
- Estimated price
- €35–210
Flights from Catania–Fontanarossa Airport to Bologna Guglielmo Marconi Airport via Bari
- Ave. Duration
- 3h 50m
- When
- Monday, Wednesday, Thursday, and Saturday
- Estimated price
- €35–210
Flights from Catania–Fontanarossa Airport to Bologna Guglielmo Marconi Airport via Malta
- Ave. Duration
- 3h 50m
- When
- Tuesday
- Estimated price
- €35–210
Flights from Palermo Airport to Pisa International Airport
- Ave. Duration
- 1h 20m
- When
- Every day
- Estimated price
- €35–200
- Website
- ita-airways.com
Flights from Catania–Fontanarossa Airport to Florence Peretola Airport via Rome
- Ave. Duration
- 3h 45m
- When
- Every day
- Estimated price
- €90–190
Flights from Catania–Fontanarossa Airport to Bologna Guglielmo Marconi Airport via Rome
- Ave. Duration
- 3h 57m
- When
- Every day
- Estimated price
- €85–210
- Website
- flyulendo.com
Flights from Catania–Fontanarossa Airport to Bologna Guglielmo Marconi Airport
- Ave. Duration
- 1h 45m
- When
- Every day
- Estimated price
- €15–95
Flights from Palermo Airport to Pisa International Airport
- Ave. Duration
- 1h 30m
- When
- Every day
- Estimated price
- €16–65
- Website
- volotea.com
Flights from Catania–Fontanarossa Airport to Florence Peretola Airport
- Ave. Duration
- 1h 40m
- When
- Every day
- Estimated price
- €16–110
Flights from Catania–Fontanarossa Airport to Florence Peretola Airport via Rome
- Ave. Duration
- 4h 5m
- When
- Every day
- Estimated price
- €90–190
- Website
- vueling.com
Flights from Catania–Fontanarossa Airport to Florence Peretola Airport
- Ave. Duration
- 1h 35m
- When
- Wednesday and Saturday
- Estimated price
- €35–190
- Phone
- +39 06 5210550
- Website
- Trenitalia Frecce
Train from Villa S.Giovanni to Firenze S.M.N.
- Ave. Duration
- 6h 54m
- Frequency
- 3 times a day
- Estimated price
- €120–210
- Website
- Trenitalia Frecce
Train from Bologna Centrale to Firenze S.M.N.
- Ave. Duration
- 37 min
- Frequency
- Every 30 minutes
- Estimated price
- €12–22
- Website
- Trenitalia Frecce
- Phone
- +39 06 8937 1892
- Website
- Italo Treno
Train from Villa S.Giovanni to Firenze S.M.N.
- Ave. Duration
- 7h 23m
- Frequency
- Once daily
- Estimated price
- €100–180
- Website
- Italo Treno
Train from Bologna Centrale to Firenze S.M.N.
- Ave. Duration
- 41 min
- Frequency
- 5 times a day
- Estimated price
- €11–18
- Website
- Italo Treno
- Phone
- +39.06.5210550
- Website
- Trenitalia
Train from Firenze S.M.N. to Siena
- Ave. Duration
- 1h 30m
- Frequency
- Hourly
- Estimated price
- €11–16
- Website
- Trenitalia
Train from Messina Centrale to Catania Centrale
- Ave. Duration
- 1h 48m
- Frequency
- Hourly
- Estimated price
- €11–16
- Website
- Trenitalia
Train from Firenze S.M.N. to Siena
- Ave. Duration
- 1h 30m
- Frequency
- Hourly
- Estimated price
- €11–16
- Website
- Trenitalia
Train from Chiusi-Chianciano T. to Siena
- Ave. Duration
- 1h 27m
- Frequency
- Every 2 hours
- Estimated price
- €10–15
- Website
- Trenitalia
Train from Messina Centrale to Catania Centrale
- Ave. Duration
- 1h 48m
- Frequency
- Hourly
- Estimated price
- €11–16
- Website
- Trenitalia
Train from Pisa Centrale to Empoli
- Ave. Duration
- 45 min
- Frequency
- Every 30 minutes
- Estimated price
- €5–8
- Website
- Trenitalia
Train from Empoli to Siena
- Ave. Duration
- 1h
- Frequency
- Hourly
- Estimated price
- €7–11
- Website
- Trenitalia
Train from Messina Centrale to Catania Centrale
- Ave. Duration
- 1h 48m
- Frequency
- Hourly
- Estimated price
- €11–16
- Website
- Trenitalia
Train from Bologna Centrale to Firenze S.M.N.
- Ave. Duration
- 1h 51m
- Frequency
- Twice daily
- Estimated price
- €11–15
- Website
- Trenitalia
Train from Firenze S.M.N. to Siena
- Ave. Duration
- 1h 30m
- Frequency
- Hourly
- Estimated price
- €11–16
- Website
- Trenitalia
Train from Messina Centrale to Palermo Centrale
- Ave. Duration
- 2h 54m
- Frequency
- Every 4 hours
- Estimated price
- €26–40
- Website
- Trenitalia
Train from Pisa Centrale to Empoli
- Ave. Duration
- 45 min
- Frequency
- Every 30 minutes
- Estimated price
- €5–8
- Website
- Trenitalia
Train from Empoli to Siena
- Ave. Duration
- 1h
- Frequency
- Hourly
- Estimated price
- €7–11
- Website
- Trenitalia
- Phone
- +39 06 68475475
- Website
- Trenitalia Intercity
Train from Villa S.Giovanni to Chiusi-Chianciano T.
- Ave. Duration
- 9h 25m
- Frequency
- Once a week
- Estimated price
- €80–160
- Website
- Trenitalia Intercity
Train from Bologna Centrale to Firenze S.M.N.
- Ave. Duration
- 1h 16m
- Frequency
- Once daily
- Estimated price
- €9–18
- Website
- Trenitalia Intercity
Train from Messina Centrale to Palermo Centrale
- Ave. Duration
- 3h 3m
- Frequency
- Twice daily
- Estimated price
- €23–45
- Website
- Trenitalia Intercity
- Phone
- +49 30 300 137 300
- [email protected]
- Website
- Flixbus
Bus from Messina to Siena
- Ave. Duration
- 11h 30m
- Frequency
- Once daily
- Estimated price
- €80–120
- Website
- Flixbus
- Phone
- +39 06 88 93 82 32
- Website
- Itabus S.p.A.
Bus from Messina to Siena
- Ave. Duration
- 13h 15m
- Frequency
- Once daily
- Estimated price
- €45–85
- Website
- Itabus S.p.A.
Bus from Messina Main Train Station to Florence Villa Constanza Bus Station
- Ave. Duration
- 13h 40m
- Frequency
- Twice daily
- Estimated price
- €50–90
- Website
- Itabus S.p.A.
- Phone
- +39 0362 185 0590
- [email protected]
- Website
- Onebus
Bus from Messina Main Train Station to Florence Villa Constanza Bus Station
- Ave. Duration
- 14h 14m
- Frequency
- 3 times a week
- Estimated price
- €95–140
- Website
- Onebus
- Phone
- +39 800 142 424
- [email protected]
- Website
- at-bus.it
Bus from Firenze Autostazione to Siena-Via Tozzi
- Ave. Duration
- 1h 15m
- Frequency
- Hourly
- Estimated price
- €5–6
- Schedules at
- at-bus.it
- Phone
- +39.06.5210550
- Website
- Trenitalia
Ferry from Messina Marittima to Villa S.Giovanni
- Ave. Duration
- 20 min
- Frequency
- Hourly
- Website
- Trenitalia
- Phone
- 3409848540
- [email protected]
- Website
- blujetlines.it
Ferry from Messina Marittima to Villa San Giovanni
- Ave. Duration
- 20 min
- Frequency
- Hourly
- Estimated price
- €2–3
- Schedules at
- blujetlines.it
- Phone
- +39.090.57.37
- [email protected]
- Website
- carontetourist.it
Car ferry from Messina Marittima to Villa San Giovanni
- Ave. Duration
- 30 min
- Frequency
- Hourly
- Estimated price
- €1–100
- Schedules at
- carontetourist.it
- Passenger
- €3
- Car
- €35–100
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