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How to get fromMestre to Sienaby train, bus, plane, or train (Trenitalia)

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There are 5 ways to get from Mestre to Siena by train, bus, plane, or train (Trenitalia)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train, bus

    best
    1. Take the train from Venezia Mestre to Firenze S.M.N.train train Fr
    2. Take the bus from Firenze Autostazione to Siena-Via Tozzibus bus 131R / ...
    3h 37m
    €33–61

  2. Bus via Florence

    cheapest
    1. Take the bus from Venice Mestre Train Station Bus Stop to Florence Villa Constanza Bus Stationbus bus Itabus
    2. Take the bus from Firenze Autostazione to Siena-Via Tozzibus bus 131R / ...
    5h 37m
    €18–27

  3. Bus

    1. Take the bus from Venezia, Viale Stazione (Mestre Stazione - fermata ATVO) to Sienabus bus 541
    4h 45m
    €24–40

  4. Fly, train

    1. Fly from Venice Marco Polo Airport (VCE) to Florence Peretola Airport (FLR)plane plane VCE - FLR
    2. Take the train from Firenze S.M.N. to Sienatrain train
    7h
    €110–236

  5. Train

    1. Take the train from Venezia Mestre to Firenze S.M.N.train train Fr
    2. Take the train from Firenze S.M.N. to Sienatrain train Re
    4h 21m
    €40–72

Mestre to Siena by train and bus

Calendar105Weekly Services
Duration3h 37mAverage Duration
Ticket€33Cheapest Price
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Comparing Your Travel Options

Map of how to get from Mestre to Siena.ExpandLaunch map view
  • Distance: 296.8 km
  • Duration: 3h 37m

What companies run services between Mestre, Italy and Siena, Italy?

FlixBus operates a bus from Venezia, Viale Stazione (Mestre Stazione - fermata ATVO) to Siena 5 times a week. Tickets cost €24–40 and the journey takes 4h 45m. Alternatively, you can take a train from Venezia Mestre to Siena via Firenze S.M.N. in around 4h 21m.

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