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How to get fromMexicali to Panama Cityby plane, bus, or car

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There are 4 ways to get from Mexicali to Panama City by plane, bus, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly

    best
    1. Fly from General Rodolfo Sánchez Taboada International Airport (MXL) to Tocumen International Airport (PTY)plane plane MXL - PTY
    8h 28m
    $328–1,035

  2. Bus via Mexico City

    cheapest
    1. Take the bus from Mexicali to México Politécnicobus bus
    2. Take the bus from Mexico City Politécnico Station to Tapachulabus bus
    3. Take the bus from Tapachula to San Salvadorbus bus
    4. Take the bus from Terminal San Carlos - CCA to Terminal Atlántico Nortebus bus
    5. Take the bus from Terminal Tica Bus San José to Terminal Tica Bus Panamábus bus
    4d 8h
    $286–416

  3. Drive 5,740.3 km

    1. Drive from Mexicali to Panama Citycar car 5,740.3 km
    3d 1h
    $786–1,135

  4. Bus

    1. Take the bus from Calexico Bus Station to Los Angeles Downtownbus bus
    2. Take the bus from Los Angeles to Managuabus bus
    3. Take the bus from Managua to Terminal NicaBusbus bus
    4. Take the bus from Terminal Tica Bus San José to Terminal Tica Bus Panamábus bus
    5d 14h

General Rodolfo Sánchez Taboada International Airport (MXL) to Tocumen International Airport (PTY) flights

Calendar29Weekly Planes
Duration9h 10mAverage Duration
Ticket$252Cheapest Price
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Questions & Answers

Map of how to get from Mexicali to Panama City.ExpandLaunch map view
  • Distance: 4,563.1 km
  • Duration: 8h 28m

What companies run services between Mexicali, Mexico and Panama City, Panama?

Volaris, Copa Airlines, and two other airlines fly from General Rodolfo Sánchez Taboada International Airport (MXL) to Tocumen International Airport (PTY) 4 times a day. Alternatively, you can take a bus from Mexicali to Terminal Tica Bus Panamá via Mexico City Politécnico Station, Tapachula, San Salvador, Terminal San Carlos - CCA, Terminal Atlántico Norte, and Terminal Tica Bus San José in around 4d 8h.

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