There are 6 ways to get from Mexicali to Santa Ana by bus (Greyhound), bus, train, car, plane, or tram
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus via Tijuana
best- Take the bus from Mexicali to Tijuanabus
- Take the bus from San Ysidro to Santa Anabus Lxus 3126 / ...
4h 47m$37–61Bus
cheapest- Take the bus from Mexicali to Tijuanabus
- Take the bus from Tijuana - Plaza El Mexicano to Santa Anabus Tijuana
8h 14m$32–88Bus, train
- Take the bus from Mexicali to Tijuanabus
- Take the train from San Diego to Santa Anatrain Pacific Surfliner
6h 6m$71–128Drive 200.2 mi
- Drive from Mexicali to Santa Anacar 200.2 mi
3h 45m$37–53Fly to Jack Northrop Field/Hawthorne Municipal Airport, tram, line 4 bus, train
- Fly from Imperial County Airport (IPL) to Jack Northrop Field/Hawthorne Municipal Airport (HHR)plane IPL - HHR
- Take the tram from Hawthorne / Lennox Station to Norwalk Stationtram
- Take the bus from C Line Station to Metrolink Stationbus
- Take the train from Norwalk / Santa Fe Springs to Santa Anatrain
4h 26mFly to Los Angeles International Airport, train
- Fly from Imperial County Airport (IPL) to Los Angeles International Airport (LAX)plane IPL - LAX
- Take the train from Los Angeles to Santa Anatrain
4h 43m$170–698
Mexicali to Santa Ana by bus and foot
Comparing Your Travel Options
The cheapest way to get from Mexicali to Santa Ana is to drive which costs $35 - $55 and takes 3h 45m.
The fastest way to get from Mexicali to Santa Ana is to drive which takes 3h 45m and costs $35 - $55.
No, there is no direct bus from Mexicali to Santa Ana. However, there are services departing from Mexicali and arriving at Santa Ana via San Ysidro. The journey, including transfers, takes approximately 4h 47m.
The distance between Mexicali and Santa Ana is 211 miles. The road distance is 201.4 miles.
The best way to get from Mexicali to Santa Ana without a car is to bus via Tijuana which takes 4h 47m and costs $35 - $65.
It takes approximately 4h 47m to get from Mexicali to Santa Ana, including transfers.
Mexicali to Santa Ana bus services, operated by Omnibus de Mexico, depart from Mexicali station.
Mexicali to Santa Ana bus services, operated by Omnibus de Mexico, arrive at Tijuana station.
Yes, the driving distance between Mexicali to Santa Ana is 201 miles. It takes approximately 3h 45m to drive from Mexicali to Santa Ana.
Book your Mexicali to Santa Ana bus tickets online with Omio.
What companies run services between Mexicali, Mexico and Santa Ana, CA, USA?
You can take a bus from Mexicali to Santa Ana via Tijuana and San Ysidro in around 4h 47m.
- Website
- advancedaircharters.com
Flights from Imperial County Airport to Jack Northrop Field/Hawthorne Municipal Airport
- Ave. Duration
- 1h
- When
- Every day
- Estimated price
- $120–170
- Website
- iflysouthern.com
Flights from Imperial County Airport to Los Angeles International Airport
- Ave. Duration
- 1h 31m
- When
- Every day
- Estimated price
- $140–600
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from San Diego to Santa Ana
- Ave. Duration
- 2h 1m
- Frequency
- Hourly
- Estimated price
- $50–80
- Website
- Amtrak
Train from Los Angeles to Santa Ana
- Ave. Duration
- 50 min
- Frequency
- Hourly
- Estimated price
- $19–30
- Website
- Amtrak
- Phone
- +1-323-466-3876
- [email protected]
- Website
- Metro Los Angeles
Tram from Hawthorne / Lennox Station to Norwalk Station
- Ave. Duration
- 23 min
- Frequency
- Every 15 minutes
- Estimated price
- $1–2
- Website
- Metro Los Angeles
- Phone
- (800) 371-LINK (5465)
- Website
- Metrolink Trains
Train from Norwalk / Santa Fe Springs to Santa Ana
- Ave. Duration
- 30 min
- Frequency
- Every 4 hours
- Estimated price
- $7–10
- Website
- Metrolink Trains
- Phone
- +52 664 104 7400
- [email protected]
- Website
- abc.com.mx
Bus from Mexicali to Tijuana
- Ave. Duration
- 2h 5m
- Frequency
- Every 3 hours
- Estimated price
- $19–35
- Schedules at
- abc.com.mx
- Book at
- abc.com.mx
Bus from Mexicali to Tijuana
- Ave. Duration
- 2h 5m
- Frequency
- Every 3 hours
- Estimated price
- $19–35
- Schedules at
- abc.com.mx
- Book at
- abc.com.mx
- Phone
- +1 866 691 9732
- [email protected]
- Website
- Limousine Express
Bus from San Ysidro to Santa Ana
- Ave. Duration
- 1h 30m
- Frequency
- 5 times a day
- Estimated price
- $30–45
- Website
- Limousine Express
- One Way
- $30–45
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from San Ysidro to Santa Ana
- Ave. Duration
- 2h 10m
- Frequency
- Twice daily
- Estimated price
- $18–28
- Website
- Greyhound
- Phone
- +1 562-929-5550
- Website
- Norwalk California Transit System
Bus from C Line Station to Metrolink Station
- Ave. Duration
- 18 min
- Frequency
- Hourly
- Website
- Norwalk California Transit System
- Phone
- +52 55 5141 4300
- [email protected]
- Website
- odm.com.mx
Bus from Mexicali to Tijuana
- Ave. Duration
- 2h 40m
- Frequency
- Every 30 minutes
- Estimated price
- $30–45
- Schedules at
- odm.com.mx
- Book at
- odm.com.mx
- Phone
- +52 55 4440 3187
- [email protected]
- Website
- autobuseselite.com.mx
Bus from Mexicali to Tijuana
- Ave. Duration
- 2h 48m
- Frequency
- 5 times a day
- Estimated price
- $23–35
- Schedules at
- autobuseselite.com.mx
- Book at
- autobuseselite.com.mx
- Phone
- +52 644 410 2444
- [email protected]
- Website
- tufesa.com.mx
Bus from Mexicali to Tijuana
- Ave. Duration
- 2h 40m
- Frequency
- Every 4 hours
- Estimated price
- $12–25
- Schedules at
- tufesa.com.mx
- Book at
- tufesa.com.mx
- Plus
- $12–25
- Titanium
- $13–25
- Phone
- +52 55 4440 3187
- [email protected]
- Website
- chihuahuenses.com.mx
Bus from Mexicali to Tijuana
- Ave. Duration
- 2h 20m
- Frequency
- Twice daily
- Estimated price
- $25–40
- Schedules at
- chihuahuenses.com.mx
- Book at
- chihuahuenses.com.mx
- Phone
- +52 664 299 0487
- [email protected]
- Website
- acnautobuses.com
Bus from Mexicali to Tijuana
- Ave. Duration
- 3h
- Frequency
- Once daily
- Estimated price
- $35–55
- Schedules at
- acnautobuses.com
- Book at
- acnautobuses.com
- Phone
- +1-800-231-2222
- [email protected]
- Website
- Greyhound Mexico
Bus from Tijuana - Plaza El Mexicano to Santa Ana
- Ave. Duration
- 4h 20m
- Frequency
- 3 times a day
- Estimated price
- $20–35
- Schedules at
- Greyhound Mexico
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Booking & Getting There
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