There are 5 ways to get from Mexicali to Santa Ana by bus, car, plane, or shuttle
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus
best- Take the bus from Mexicali to Santa Anabus Plus / ...
7h 16m$700–1,900Drive 522.9 km
- Drive from Mexicali to Santa Anacar 522.9 km
6h 49m$926–1,337Fly General Rodolfo Sánchez Taboada International Airport to Hermosillo International Airport, bus
- Fly from General Rodolfo Sánchez Taboada International Airport (MXL) to Hermosillo International Airport (HMO)plane MXL - HMO
- Take the bus from Hermosillo to Santa Anabus
4h 40m$3,007–7,860Bus to Tijuana International Airport, fly to Hermosillo International Airport, bus
- Take the bus from Mexicali to Tijuana International Airportbus
- Fly from Tijuana International Airport (TIJ) to Hermosillo International Airport (HMO)plane TIJ - HMO
- Take the bus from Hermosillo to Santa Anabus
8h 1m$2,078–5,361Fly Imperial County Airport to Phoenix, shuttle, bus
- Fly from Imperial County Airport (IPL) to Phoenix (PHX)plane IPL - PHX
- Take a shuttle bus from Sky Harbor International Airport to Nogales
- Take the bus from Nogales to Santa Anabus
8h 25m$5,583–8,275
Mexicali to Santa Ana by bus
Questions & Answers
The cheapest way to get from Mexicali to Santa Ana is to bus which costs $700 - $1900 and takes 7h 16m.
The fastest way to get from Mexicali to Santa Ana is to fly and bus which takes 4h 40m and costs $3000 - $8000.
Yes, there is a direct bus departing from Mexicali and arriving at Santa Ana. Services depart five times a day, and operate every day. The journey takes approximately 7h 16m.
The distance between Mexicali and Santa Ana is 521 km. The road distance is 522.9 km.
The best way to get from Mexicali to Santa Ana without a car is to bus which takes 7h 16m and costs $700 - $1900.
The bus from Mexicali to Santa Ana takes 7h 16m including transfers and departs five times a day.
Mexicali to Santa Ana bus services, operated by Tufesa Mexico, depart from Mexicali station.
Mexicali to Santa Ana bus services, operated by Tufesa Mexico, arrive at Santa Ana station.
Yes, the driving distance between Mexicali to Santa Ana is 523 km. It takes approximately 6h 49m to drive from Mexicali to Santa Ana.
Book your Mexicali to Santa Ana bus tickets online with 12go.asia.
What companies run services between Mexicali, Mexico and Santa Ana, Sonora, Mexico?
Tufesa Mexico operates a bus from Mexicali to Santa Ana hourly. Tickets cost $700–1,100 and the journey takes 7h 16m. Three other operators also service this route.
- Website
- volaris.com
Flights from General Rodolfo Sánchez Taboada International Airport to Hermosillo International Airport
- Ave. Duration
- 1h 11m
- When
- Tuesday and Thursday
- Estimated price
- $1,300–5,000
Flights from Tijuana International Airport to Hermosillo International Airport
- Ave. Duration
- 1h 23m
- When
- Every day
- Estimated price
- $1,400–3,600
- Website
- iflysouthern.com
Flights from Imperial County Airport to Phoenix
- Ave. Duration
- 1h 38m
- When
- Every day
- Estimated price
- $1,800–4,200
- Phone
- +52 644 410 2444
- [email protected]
- Website
- tufesa.com.mx
Bus from Mexicali to Santa Ana
- Ave. Duration
- 7h 16m
- Frequency
- Hourly
- Estimated price
- $700–1,100
- Schedules at
- tufesa.com.mx
- Book at
- tufesa.com.mx
- Plus
- $700–1,000
- Titanium
- $750–1,100
Bus from Hermosillo to Santa Ana
- Ave. Duration
- 3h
- Frequency
- 3 times a day
- Estimated price
- $222–460
- Schedules at
- tufesa.com.mx
- Book at
- tufesa.com.mx
- Plus
- $230–460
- Titanium
- $250–460
Bus from Hermosillo to Santa Ana
- Ave. Duration
- 3h
- Frequency
- 3 times a day
- Estimated price
- $222–460
- Schedules at
- tufesa.com.mx
- Book at
- tufesa.com.mx
- Plus
- $230–460
- Titanium
- $250–460
- Phone
- +52 55 4440 3187
- [email protected]
- Website
- autobuseselite.com.mx
Bus from Mexicali to Santa Ana
- Ave. Duration
- 7h 53m
- Frequency
- 4 times a day
- Estimated price
- $950–1,400
- Schedules at
- autobuseselite.com.mx
- Book at
- autobuseselite.com.mx
Bus from Hermosillo to Santa Ana
- Ave. Duration
- 2h
- Frequency
- 3 times a day
- Estimated price
- $430–650
- Schedules at
- autobuseselite.com.mx
- Book at
- autobuseselite.com.mx
Bus from Hermosillo to Santa Ana
- Ave. Duration
- 2h
- Frequency
- 3 times a day
- Estimated price
- $430–650
- Schedules at
- autobuseselite.com.mx
- Book at
- autobuseselite.com.mx
- Phone
- +52 55 4440 3187
- [email protected]
- Website
- chihuahuenses.com.mx
Bus from Mexicali to Santa Ana
- Ave. Duration
- 7h 50m
- Frequency
- 4 times a day
- Estimated price
- $900–1,900
- Schedules at
- chihuahuenses.com.mx
- Book at
- chihuahuenses.com.mx
- Phone
- +52 664 299 0487
- [email protected]
- Website
- acnautobuses.com
Bus from Mexicali to Santa Ana
- Ave. Duration
- 6h 10m
- Frequency
- Once daily
- Estimated price
- $850–1,200
- Schedules at
- acnautobuses.com
- Book at
- acnautobuses.com
- Phone
- +52 800 624 6618
- [email protected]
- Website
- albatrosautobuses.mx
Bus from Hermosillo to Santa Ana
- Ave. Duration
- 2h 45m
- Frequency
- Every 30 minutes
- Estimated price
- $160–240
- Schedules at
- albatrosautobuses.mx
- Book at
- albatrosautobuses.mx
Bus from Hermosillo to Santa Ana
- Ave. Duration
- 2h 45m
- Frequency
- Every 30 minutes
- Estimated price
- $160–240
- Schedules at
- albatrosautobuses.mx
- Book at
- albatrosautobuses.mx
Bus from Nogales to Santa Ana
- Ave. Duration
- 1h 40m
- Frequency
- Hourly
- Estimated price
- $130–190
- Schedules at
- albatrosautobuses.mx
- Book at
- albatrosautobuses.mx
- Phone
- +52 55 5141 4300
- [email protected]
- Website
- odm.com.mx
Bus from Hermosillo to Santa Ana
- Ave. Duration
- 3h 9m
- Frequency
- Every 4 hours
- Estimated price
- $600–850
- Schedules at
- odm.com.mx
- Book at
- odm.com.mx
Bus from Hermosillo to Santa Ana
- Ave. Duration
- 3h 9m
- Frequency
- Every 4 hours
- Estimated price
- $600–850
- Schedules at
- odm.com.mx
- Book at
- odm.com.mx
- Phone
- +52 664 104 7400
- [email protected]
- Website
- abc.com.mx
Bus from Mexicali to Tijuana International Airport
- Ave. Duration
- 2h 30m
- Frequency
- Twice daily
- Estimated price
- $340–600
- Schedules at
- abc.com.mx
- Book at
- abc.com.mx
- Phone
- +1-480-710-3441
- [email protected]
- Website
- Airport Shuttle of Phoenix
Shuttle from Sky Harbor International Airport to Nogales
- Ave. Duration
- 3h 30m
- Frequency
- On demand
- Estimated price
- $3,584
- Website
- Airport Shuttle of Phoenix
Want to know more about travelling around Mexico
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
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