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How to get fromMexico Beach to Florida Keysby car, plane, taxi, or shuttle

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There are 6 ways to get from Mexico Beach to Florida Keys by car, plane, taxi, or shuttle

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Drive  678.9 mi

    best
    1. Drive from Mexico Beach to Florida Keyscar car 678.9 mi
    13h 30m
    $124–179

  2. Drive to Tallahassee, fly to Key West International Airport

    1. Drive from Mexico Beach to Tallahassee (TLH)car car
    2. Fly from Tallahassee (TLH) to Key West International Airport (EYW)plane plane TLH - EYW
    8h 51m
    $165–520

  3. Drive to Destin–Fort Walton Beach Airport, fly to Key West International Airport

    1. Drive from Mexico Beach to Destin–Fort Walton Beach Airport (VPS)car car
    2. Fly from Destin–Fort Walton Beach Airport (VPS) to Key West International Airport (EYW)plane plane VPS - EYW
    9h 3m
    $149–428

  4. Taxi to Northwest Florida Beaches International Airport, fly to Key West International Airport

    1. Take the taxi from Tyndall Pkwy & Walmart Parking Lot to Northwest Florida Beaches International Airport (ECP)taxi taxi
    2. Fly from Northwest Florida Beaches International Airport (ECP) to Key West International Airport (EYW)plane plane ECP - EYW
    9h 21m
    $214–536

  5. Drive to Tallahassee, fly to Miami International Airport, shuttle

    1. Drive from Mexico Beach to Tallahassee (TLH)car car
    2. Fly from Tallahassee (TLH) to Miami International Airport (MIA)plane plane TLH - MIA
    3. Take a shuttle bus from Miami, FL - International Airport to Big Pine Key, FLshuttle bus
    9h 11m
    $245–690

  6. Drive to Destin–Fort Walton Beach Airport, fly to Miami International Airport, shuttle

    1. Drive from Mexico Beach to Destin–Fort Walton Beach Airport (VPS)car car
    2. Fly from Destin–Fort Walton Beach Airport (VPS) to Miami International Airport (MIA)plane plane VPS - MIA
    3. Take a shuttle bus from Miami, FL - International Airport to Big Pine Key, FLshuttle bus
    9h 26m
    $229–578

Tallahassee (TLH) to Key West International Airport (EYW) flights

Calendar56Weekly Planes
Duration5h 2mAverage Duration
Ticket$70Cheapest Price
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Comparing Your Travel Options

Map of how to get from Mexico Beach to Florida Keys.ExpandLaunch map view
  • Distance: 678.9 mi
  • Duration: 13h 30m

What companies run services between Mexico Beach, FL, USA and Florida Keys, FL, USA?

You can drive from Mexico Beach to Florida Keys in around 13h 30m.

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