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How to get fromMexico City to Cayo Santa Maríaby plane or bus

Find Transport to Cayo Santa María

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There are 4 ways to get from Mexico City to Cayo Santa María by plane or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Benito Juárez International Airport to Abel Santamaría Airport, bus

    best
    1. Fly from Benito Juárez International Airport (MEX) to Abel Santamaría Airport (SNU)plane plane MEX - SNU
    2. Take the bus from Santa Clara to Cayo Santa Maríabus bus
    11h 36m
    $141–585

  2. Fly Benito Juárez International Airport to Juan Gualberto Gómez International Airport, bus

    1. Fly from Benito Juárez International Airport (MEX) to Juan Gualberto Gómez International Airport (VRA)plane plane MEX - VRA
    2. Take the bus from Varadero Airport to Santa Clarabus bus
    3. Take the bus from Santa Clara to Cayo Santa Maríabus bus
    22h 4m
    $145–594

  3. Fly Benito Juárez International Airport to José Martí International Airport, bus

    1. Fly from Benito Juárez International Airport (MEX) to José Martí International Airport (HAV)plane plane MEX - HAV
    2. Take the bus from Havana Airport to Matanzasbus bus
    3. Take the bus from Matanzas to Santa Clarabus bus
    4. Take the bus from Santa Clara to Cayo Santa Maríabus bus
    15h 11m
    $261–1,340

  4. Fly Felipe Ángeles International Airport to José Martí International Airport, bus

    1. Fly from Felipe Ángeles International Airport (NLU) to José Martí International Airport (HAV)plane plane NLU - HAV
    2. Take the bus from Havana Airport to Matanzasbus bus
    3. Take the bus from Matanzas to Santa Clarabus bus
    4. Take the bus from Santa Clara to Cayo Santa Maríabus bus
    15h 11m
    $214–500

Benito Juárez International Airport (MEX) to Abel Santamaría Airport (SNU) flights

Calendar7Weekly Planes
Duration6h 10mAverage Duration
Ticket$123Cheapest Price
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Questions & Answers

Map of how to get from Mexico City to Cayo Santa María.ExpandLaunch map view
  • Distance: 2,149.4 km
  • Duration: 11h 36m

What companies run services between Mexico City, Mexico and Cayo Santa María, Villa Clara, Cuba?

There is no direct connection from Mexico City to Cayo Santa María. However, you can take the line 4 bus to Terminal 1 - Aeropuerto, walk to Benito Juárez International Airport (MEX) airport, fly to Abel Santamaría Airport (SNU), take the taxi to Santa Clara, then take the bus to Cayo Santa María. Alternatively, you can take the line 4 bus to Terminal 1 - Aeropuerto, walk to Benito Juárez International Airport (MEX) airport, fly to Juan Gualberto Gómez International Airport (VRA), walk to Varadero Airport, take the bus to Santa Clara, then take the bus to Cayo Santa María.

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