There are 10 ways to get from Mexico City to Santa Ana by plane, bus, train, or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Benito Juárez International Airport to John Wayne Airport Orange County
best- Fly from Benito Juárez International Airport (MEX) to John Wayne Airport Orange County (SNA)plane MEX - SNA
6h 29m$159–687Bus via Morelia
cheapest- Take the bus from Terminal Poniente - Observatorio to Moreliabus
- Take the bus from Morelia to Santa Anabus
45h 30m$120–305Bus, train via San Antonio
- Take the bus from Terminal Central de Autobuses del Norte to San Antoniobus
- Take the train from San Antonio Station to Los Angelestrain
- Take the train from Los Angeles to Santa Anatrain
2d 3h$911–1,440Drive 1,794.3 mi
- Drive from Mexico City to Santa Anacar 1,794.3 mi
33h 7m$395–571Fly Benito Juárez International Airport to Tijuana International Airport, bus
- Fly from Benito Juárez International Airport (MEX) to Tijuana International Airport (TIJ)plane MEX - TIJ
- Take the bus from Tijuana Aeropuerto, B.C. to Santa Anabus
8h$130–317Fly Felipe Ángeles International Airport to Tijuana International Airport, bus
- Fly from Felipe Ángeles International Airport (NLU) to Tijuana International Airport (TIJ)plane NLU - TIJ
- Take the bus from Tijuana Aeropuerto, B.C. to Santa Anabus
8h 39m$128–326Fly Licenciado Adolfo López Mateos International Airport to Tijuana International Airport, bus
- Fly from Licenciado Adolfo López Mateos International Airport (TLC) to Tijuana International Airport (TIJ)plane TLC - TIJ
- Take the bus from Tijuana Aeropuerto, B.C. to Santa Anabus
8h 58m$168–360Fly Benito Juárez International Airport to Los Angeles International Airport, train
- Fly from Benito Juárez International Airport (MEX) to Los Angeles International Airport (LAX)plane MEX - LAX
- Take the train from Los Angeles to Santa Anatrain
8h 33m$176–325Bus
- Take the bus from Terminal Central de Autobuses del Norte to Tijuanabus
- Take the bus from Tijuana Central, B.C. to Santa Anabus Lxus 3126 / ...
47h 21m$204–466Bus, train
- Take the bus from Terminal Central de Autobuses del Norte to Los Angelesbus
- Take the train from Los Angeles to Santa Anatrain Pacific Surfliner
2d 10h$217–262
Mexico City to Santa Ana by bus
Comparing Your Travel Options
The cheapest way to get from Mexico City to Santa Ana is to fly and bus which costs $120 - $330 and takes 8h 39m.
The fastest way to get from Mexico City to Santa Ana is to fly which takes 6h 29m and costs $150 - $700.
No, there is no direct bus from Mexico City to Santa Ana. However, there are services departing from Terminal Poniente - Observatorio and arriving at Santa Ana via Morelia. The journey, including transfers, takes approximately 45h 30m.
The distance between Mexico City and Santa Ana is 1535 miles. The road distance is 1804.7 miles.
The best way to get from Mexico City to Santa Ana without a car is to bus via Morelia which takes 45h 30m and costs $120 - $310.
It takes approximately 6h 29m to get from Mexico City to Santa Ana, including transfers.
Mexico City to Santa Ana bus services, operated by Autovías La Línea, depart from Terminal Poniente - Observatorio station.
The best way to get from Mexico City to Santa Ana is to fly which takes 6h 29m and costs $150 - $700. Alternatively, you can bus via Morelia, which costs $120 - $310 and takes 45h 30m.
Mexico City to Santa Ana bus services, operated by Autovías La Línea, arrive at Morelia station.
Santa Ana is 2h behind Mexico City. It is currently 4:49 PM in Mexico City and 2:49 PM in Santa Ana.
What companies run services between Mexico City, Mexico and Santa Ana, CA, USA?
Aeroméxico, United Airlines, and three other airlines fly from Benito Juárez International Airport (MEX) to John Wayne Airport Orange County (SNA) every 4 hours. Alternatively, you can take a bus from Terminal Poniente - Observatorio to Santa Ana via Morelia in around 45h 30m.
- Website
- volaris.com
Flights from Benito Juárez International Airport to John Wayne Airport Orange County via Las Vegas
- Ave. Duration
- 9h 6m
- When
- Monday, Thursday, Friday, and Sunday
- Estimated price
- $250–750
Flights from Benito Juárez International Airport to Tijuana International Airport
- Ave. Duration
- 3h 38m
- When
- Every day
- Estimated price
- $110–270
Flights from Benito Juárez International Airport to Tijuana International Airport via Hermosillo
- Ave. Duration
- 6h 42m
- When
- Every day
- Estimated price
- $110–270
Flights from Benito Juárez International Airport to Tijuana International Airport via Los Mochis
- Ave. Duration
- 5h 30m
- When
- Every day
- Estimated price
- $110–270
Flights from Benito Juárez International Airport to Tijuana International Airport via Culiacan
- Ave. Duration
- 7h 22m
- When
- Every day
- Estimated price
- $110–270
Flights from Felipe Ángeles International Airport to Tijuana International Airport
- Ave. Duration
- 3h 29m
- When
- Every day
- Estimated price
- $100–270
Flights from Licenciado Adolfo López Mateos International Airport to Tijuana International Airport
- Ave. Duration
- 3h 28m
- When
- Every day
- Estimated price
- $150–310
Flights from Licenciado Adolfo López Mateos International Airport to Tijuana International Airport via Guadalajara
- Ave. Duration
- 5h 57m
- When
- Every day
- Estimated price
- $150–310
Flights from Licenciado Adolfo López Mateos International Airport to Tijuana International Airport via Puerto Vallarta
- Ave. Duration
- 5h 30m
- When
- Every day
- Estimated price
- $150–310
Flights from Benito Juárez International Airport to Los Angeles International Airport
- Ave. Duration
- 4h 5m
- When
- Every day
- Estimated price
- $150–280
Flights from Benito Juárez International Airport to Los Angeles International Airport via Guadalajara
- Ave. Duration
- 6h 32m
- When
- Every day
- Estimated price
- $150–280
- Website
- aeromexico.com
Flights from Benito Juárez International Airport to John Wayne Airport Orange County
- Ave. Duration
- 4h 20m
- When
- Every day
- Estimated price
- $130–650
Flights from Benito Juárez International Airport to Tijuana International Airport
- Ave. Duration
- 3h 54m
- When
- Every day
- Estimated price
- $100–490
Flights from Benito Juárez International Airport to Los Angeles International Airport
- Ave. Duration
- 4h 19m
- When
- Every day
- Estimated price
- $80–360
Flights from Benito Juárez International Airport to Los Angeles International Airport via Guadalajara
- Ave. Duration
- 6h 15m
- When
- Every day
- Estimated price
- $80–360
- Website
- vivaaerobus.com
Flights from Benito Juárez International Airport to Tijuana International Airport
- Ave. Duration
- 3h 31m
- When
- Every day
- Estimated price
- $95–280
Flights from Felipe Ángeles International Airport to Tijuana International Airport
- Ave. Duration
- 3h 29m
- When
- Every day
- Estimated price
- $75–270
Flights from Licenciado Adolfo López Mateos International Airport to Tijuana International Airport via San Jose Cabo
- Ave. Duration
- 6h 26m
- When
- Every day
- Estimated price
- $120–230
Flights from Licenciado Adolfo López Mateos International Airport to Tijuana International Airport via Monterrey
- Ave. Duration
- 7h 27m
- When
- Monday, Tuesday, Wednesday, Thursday, Saturday, and Sunday
- Estimated price
- $120–230
Flights from Licenciado Adolfo López Mateos International Airport to Tijuana International Airport via Puerto Vallarta
- Ave. Duration
- 7h 54m
- When
- Every day
- Estimated price
- $120–230
Flights from Benito Juárez International Airport to Los Angeles International Airport
- Ave. Duration
- 3h 50m
- When
- Every day
- Estimated price
- $150–280
Flights from Benito Juárez International Airport to Los Angeles International Airport via Guadalajara
- Ave. Duration
- 5h 52m
- When
- Every day
- Estimated price
- $150–280
- Website
- delta.com
Flights from Benito Juárez International Airport to Los Angeles International Airport
- Ave. Duration
- 4h 19m
- When
- Every day
- Estimated price
- $80–360
Flights from Benito Juárez International Airport to Los Angeles International Airport via Guadalajara
- Ave. Duration
- 6h 15m
- When
- Every day
- Estimated price
- $80–360
- Website
- united.com
Flights from Benito Juárez International Airport to John Wayne Airport Orange County via Houston
- Ave. Duration
- 8h 15m
- When
- Every day
- Estimated price
- $170–750
- Website
- flyfrontier.com
Flights from Benito Juárez International Airport to John Wayne Airport Orange County via Las Vegas
- Ave. Duration
- 9h 6m
- When
- Monday, Thursday, Friday, and Sunday
- Estimated price
- $250–750
Flights from Benito Juárez International Airport to Los Angeles International Airport
- Ave. Duration
- 4h 5m
- When
- Every day
- Estimated price
- $150–280
- Website
- aa.com
Flights from Benito Juárez International Airport to John Wayne Airport Orange County via Phoenix
- Ave. Duration
- 8h 27m
- When
- Thursday and Sunday
- Estimated price
- $140–650
Flights from Benito Juárez International Airport to Los Angeles International Airport
- Ave. Duration
- 4h 9m
- When
- Every day
- Estimated price
- $80–360
- Website
- csair.com
Flights from Benito Juárez International Airport to Tijuana International Airport
- Ave. Duration
- 4h
- When
- Wednesday, Friday, and Sunday
- Estimated price
- $320–700
- Website
- hainanairlines.com
Flights from Benito Juárez International Airport to Tijuana International Airport
- Ave. Duration
- 3h 35m
- When
- Every day
- Estimated price
- $340–800
- Website
- mexicana.gob.mx
Flights from Felipe Ángeles International Airport to Tijuana International Airport
- Ave. Duration
- 3h 30m
- When
- Every day
- Estimated price
- $90–420
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from San Antonio Station to Los Angeles
- Ave. Duration
- 28h 50m
- Frequency
- 6 times a week
- Estimated price
- $750–1,200
- Website
- Amtrak
Train from Los Angeles to Santa Ana
- Ave. Duration
- 50 min
- Frequency
- Hourly
- Estimated price
- $19–30
- Website
- Amtrak
Train from Los Angeles to Santa Ana
- Ave. Duration
- 50 min
- Frequency
- Hourly
- Estimated price
- $19–30
- Website
- Amtrak
Train from Los Angeles to Santa Ana
- Ave. Duration
- 50 min
- Frequency
- Hourly
- Estimated price
- $19–30
- Website
- Amtrak
- Phone
- 800 622 22 22
- [email protected]
- Website
- Autovías
Bus from Terminal Poniente - Observatorio to Morelia
- Ave. Duration
- 4h
- Frequency
- Hourly
- Estimated price
- $29–65
- Website
- Autovías
- Phone
- +52 800 800 0386
- [email protected]
- Website
- ETN Turistar
Bus from Terminal Poniente - Observatorio to Morelia
- Ave. Duration
- 4h
- Frequency
- Once daily
- Estimated price
- $40–75
- Website
- ETN Turistar
- Phone
- +52 664 299 0487
- [email protected]
- Website
- acnautobuses.com
Bus from Morelia to Santa Ana
- Ave. Duration
- 40h 30m
- Frequency
- Once daily
- Estimated price
- $90–230
- Schedules at
- acnautobuses.com
- Book at
- acnautobuses.com
- Phone
- +1 800 923 1799
- [email protected]
- Website
- Omnibus Express (OMEX VIP)
Bus from Terminal Central de Autobuses del Norte to San Antonio
- Ave. Duration
- 20h 2m
- Frequency
- Once daily
- Estimated price
- $140–210
- Schedules at
- Omnibus Express (OMEX VIP)
- Phone
- +1 866 691 9732
- [email protected]
- Website
- Limousine Express
Bus from Tijuana Aeropuerto, B.C. to Santa Ana
- Ave. Duration
- 2h 30m
- Frequency
- 5 times a day
- Estimated price
- $30–45
- Website
- Limousine Express
- One Way
- $30–45
Bus from Tijuana Aeropuerto, B.C. to Santa Ana
- Ave. Duration
- 2h 30m
- Frequency
- 5 times a day
- Estimated price
- $30–45
- Website
- Limousine Express
- One Way
- $30–45
Bus from Tijuana Aeropuerto, B.C. to Santa Ana
- Ave. Duration
- 2h 30m
- Frequency
- 5 times a day
- Estimated price
- $30–45
- Website
- Limousine Express
- One Way
- $30–45
Bus from Tijuana Central, B.C. to Santa Ana
- Ave. Duration
- 3h 30m
- Frequency
- 5 times a day
- Estimated price
- $30–45
- Website
- Limousine Express
- One Way
- $30–45
- Phone
- +52 55 5141 4300
- [email protected]
- Website
- odm.com.mx
Bus from Terminal Central de Autobuses del Norte to Tijuana
- Ave. Duration
- 42h 51m
- Frequency
- Every 4 hours
- Estimated price
- $170–430
- Schedules at
- odm.com.mx
- Book at
- odm.com.mx
- Phone
- +52 55 4440 3187
- [email protected]
- Website
- autobuseselite.com.mx
Bus from Terminal Central de Autobuses del Norte to Tijuana
- Ave. Duration
- 44h
- Frequency
- Every 4 hours
- Estimated price
- $170–340
- Schedules at
- autobuseselite.com.mx
- Book at
- autobuseselite.com.mx
- Phone
- +1 213 368 1172
- [email protected]
- Website
- busesusatours.com
Bus from Terminal Central de Autobuses del Norte to Los Angeles
- Ave. Duration
- 2d 8h
- Frequency
- Once a week
- Estimated price
- $190–230
- Schedules at
- busesusatours.com
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Booking & Getting There
Yes, the driving distance between Mexico City to Santa Ana is 1805 miles. It takes approximately 33h 7m to drive from Mexico City to Santa Ana.
Book your Mexico City to Santa Ana bus tickets online with Omio.
There are 113+ hotels available in Santa Ana.

































