Rome2Rio

How to get fromMexico City to Santa Cruzby plane, train, bus, bus (Greyhound, Amtrak), car, subway, taxi, bus (Amtrak), or bus (Greyhound, Flixbus, Amtrak)

Find Transport to Santa Cruz

See all options

There are 11 ways to get from Mexico City to Santa Cruz by plane, train, bus, bus (Greyhound, Amtrak), car, subway, taxi, bus (Amtrak), or bus (Greyhound, Flixbus, Amtrak)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Benito Juárez International Airport to San Francisco International Airport, Caltrain, bus

    best
    1. Fly from Benito Juárez International Airport (MEX) to San Francisco International Airport (SFO)plane plane MEX - SFO
    2. Take the train from Millbrae Caltrain Southbound to San Jose Diridon Caltrain Southboundtrain train
    3. Take the bus from Diridon Station to Soquel Ave & Frontbus bus
    8h 59m
    $455–1,037
  2. Fly Benito Juárez International Airport to Monterey Regional Airport

    cheapest
    1. Fly from Benito Juárez International Airport (MEX) to Monterey Regional Airport (MRY)plane plane MEX - MRY
    14h 18m
    $129–570
  3. Bus via Mexicali

    1. Take the bus from Terminal Central Del Sur - Taxqueña to Mexicalibus bus
    2. Take the bus from Mexicali to Tijuanabus bus
    3. Take the bus from San Ysidro Bus Terminal to San Jose Diridon Stationbus bus
    4. Take the bus from Diridon Station to Soquel Ave & Frontbus bus 17
    2d 5h
    $292–538
  4. Drive 2,145.5 mi

    1. Drive from Mexico City to Santa Cruzcar car 2,145.5 mi
    39h 11m
    $392–566
  5. Fly Benito Juárez International Airport to Norman Y. Mineta San José International Airport, bus

    1. Fly from Benito Juárez International Airport (MEX) to Norman Y. Mineta San José International Airport (SJC)plane plane MEX - SJC
    2. Take the bus from Diridon Station to Soquel Ave & Frontbus bus
    10h 13m
    $156–675
  6. Fly Benito Juárez International Airport to Oakland International Airport, BART, bus

    1. Fly from Benito Juárez International Airport (MEX) to Oakland International Airport (OAK)plane plane MEX - OAK
    2. Take the subway from Coliseum to Berryessa / North San Josesubway subway
    3. Take the bus from Diridon Station to Soquel Ave & Frontbus bus
    9h 9m
    $190–633
  7. Bus, taxi to General Francisco Mujica International Airport, fly to Norman Y. Mineta San José International Airport

    1. Take the bus from Terminal Poniente - Observatorio to Caseta Zinapécuarobus bus
    2. Take the taxi from Caseta Zinapécuaro to General Francisco Mujica International Airport (MLM)taxi taxi
    3. Fly from General Francisco Mujica International Airport (MLM) to Norman Y. Mineta San José International Airport (SJC)plane plane MLM - SJC
    4. Take the bus from Diridon Station to Soquel Ave & Frontbus bus
    11h 52m
    $417–1,138
  8. Bus, taxi to General Francisco Mujica International Airport, fly to Oakland International Airport, BART

    1. Take the bus from Terminal Poniente - Observatorio to Caseta Zinapécuarobus bus
    2. Take the taxi from Caseta Zinapécuaro to General Francisco Mujica International Airport (MLM)taxi taxi
    3. Fly from General Francisco Mujica International Airport (MLM) to Oakland International Airport (OAK)plane plane MLM - OAK
    4. Take the subway from Coliseum to Berryessa / North San Josesubway subway
    5. Take the bus from Diridon Station to Soquel Ave & Frontbus bus
    12h 46m
    $321–746
  9. Bus

    1. Take the bus from Terminal Poniente - Observatorio to Moreliabus bus
    2. Take the bus from Morelia to Santa Anabus bus
    3. Take the bus from Santa Ana Bus Stop to San Jose Diridon Stationbus bus
    4. Take the bus from Diridon Station to Soquel Ave & Frontbus bus 17
    2d 7h
    $197–456
  10. Bus #2

    1. Take the bus from Terminal Central de Autobuses del Norte to Nogalesbus bus
    2. Take the bus from Nogales to Gilroybus bus
    3. Take the bus from Gilroy Transit Center to San Jose Diridonbus bus 68
    4. Take the bus from Diridon Station to Ocean & Waterbus bus 17
    2d 10h
    $312–620
  11. Bus #3

    1. Take the bus from Terminal Central de Autobuses del Norte to Los Angelesbus bus
    2. Take the bus from Los Angeles Union Station to San Jose Diridon Stationbus bus
    3. Take the bus from Diridon Station to Soquel Ave & Frontbus bus 17
    2d 17h
    $258–346

Mexico City to Santa Cruz by bus

Calendar7Weekly Buses
Duration2d 7hAverage Duration
Ticket$197Cheapest Price
See schedules

Questions & Answers

What companies run services between Mexico City, Mexico and Santa Cruz, CA, USA?

You can take a bus from Terminal Central Del Sur - Taxqueña to Soquel Ave & Front via Mexicali, Tijuana, San Ysidro Bus Terminal, San Jose Diridon Station, and Diridon Station in around 2d 5h. Alternatively, American Airlines, United Airlines, and Aeroméxico fly from Benito Juárez International Airport (MEX) to Monterey Regional Airport (MRY) every 4 hours.

Airlines
Train operators
Bus operators
Other operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

More Questions & Answers