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How to get fromMexico City to Santiago de Cubaby plane, shuttle, or bus

Find Transport to Santiago de Cuba

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There are 6 ways to get from Mexico City to Santiago de Cuba by plane, shuttle, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Felipe Ángeles International Airport to Frank País International Airport, shuttle

    best
    1. Fly from Felipe Ángeles International Airport (NLU) to Frank País International Airport (HOG)plane plane NLU - HOG
    2. Take a shuttle bus from Hotel Pernik Holguin to Melia Santiago de Cubashuttle bus
    20h 55m
    $176–700

  2. Fly Benito Juárez International Airport to Ignacio Agramonte International Airport, bus

    cheapest
    1. Fly from Benito Juárez International Airport (MEX) to Ignacio Agramonte International Airport (CMW)plane plane MEX - CMW
    2. Take the bus from Camagüey to Santiago de Cubabus bus
    13h 54m
    $114–559

  3. Fly Benito Juárez International Airport to Antonio Maceo International Airport

    1. Fly from Benito Juárez International Airport (MEX) to Antonio Maceo International Airport (SCU)plane plane MEX - SCU
    10h 22m
    $143–655

  4. Fly Felipe Ángeles International Airport to Antonio Maceo International Airport

    1. Fly from Felipe Ángeles International Airport (NLU) to Antonio Maceo International Airport (SCU)plane plane NLU - SCU
    10h 22m
    $186–715

  5. Fly Benito Juárez International Airport to Frank País International Airport, shuttle

    1. Fly from Benito Juárez International Airport (MEX) to Frank País International Airport (HOG)plane plane MEX - HOG
    2. Take a shuttle bus from Hotel Pernik Holguin to Melia Santiago de Cubashuttle bus
    12h 30m
    $163–690

  6. Fly Felipe Ángeles International Airport to Ignacio Agramonte International Airport, bus

    1. Fly from Felipe Ángeles International Airport (NLU) to Ignacio Agramonte International Airport (CMW)plane plane NLU - CMW
    2. Take the bus from Camagüey to Santiago de Cubabus bus
    19h 54m
    $147–569

Felipe Ángeles International Airport (NLU) to Frank País International Airport (HOG) flights

Calendar9Weekly Planes
Duration21h 59mAverage Duration
Ticket$143Cheapest Price
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Questions & Answers

Map of how to get from Mexico City to Santiago de Cuba.ExpandLaunch map view
  • Distance: 2,558.9 km
  • Duration: 20h 55m

What companies run services between Mexico City, Mexico and Santiago de Cuba?

Aeroméxico, Sky High Aviation Services, and three other airlines fly from Benito Juárez International Airport (MEX) to Antonio Maceo International Airport (SCU) twice daily.

Airlines
Bus operators

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