There are 9 ways to get from Mexico City to St. Louis by plane, bus (Flixbus, Greyhound), bus, train, car, or taxi
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Benito Juárez International Airport to Lambert–St. Louis International Airport
best- Fly from Benito Juárez International Airport (MEX) to Lambert–St. Louis International Airport (STL)plane MEX - STL
8h 3m$143–705Fly Benito Juárez International Airport to Barkley Regional Airport, drive
cheapest- Fly from Benito Juárez International Airport (MEX) to Barkley Regional Airport (PAH)plane MEX - PAH
- Drive from Barkley Regional Airport (PAH) to St. Louiscar
11h 16m$130–552Bus
- Take the bus from Terminal Central de Autobuses del Norte to Dallasbus
- Take the bus from Downtown Dallas / Deep Ellum to Oklahoma City Bus Stationbus
- Take the bus from Oklahoma City Bus Station to St Louis Bus Stationbus
42h 34m$294–410Bus, train
- Take the bus from Terminal Central de Autobuses del Norte to San Marcosbus
- Take the train from San Marcos Amtrak to St. Louistrain Texas Eagle
45h 33m$388–822Drive 1,707.2 mi
- Drive from Mexico City to St. Louiscar 1,707.2 mi
31h 9m$312–450Bus, taxi to General Francisco Mujica International Airport, fly to Lambert–St. Louis International Airport
- Take the bus from Terminal Poniente - Observatorio to Caseta Zinapécuarobus
- Take the taxi from Caseta Zinapécuaro to General Francisco Mujica International Airport (MLM)taxi
- Fly from General Francisco Mujica International Airport (MLM) to Lambert–St. Louis International Airport (STL)plane MLM - STL
13h 5m$337–1,249Bus to Hermanos Serdán International Airport, fly to Lambert–St. Louis International Airport
- Take the bus from Terminal Central de Autobuses del Norte to Puebla Terminal CAPUbus
- Fly from Hermanos Serdán International Airport (PBC) to Lambert–St. Louis International Airport (STL)plane PBC - STL
12h 14m$212–933Train, bus
- Take the train from Estación Observatorio to Estación Toluca Centrotrain
- Take the bus from Toluca to San Marcosbus
- Take the train from San Marcos Amtrak to St. Louistrain
45h 51m$384–786Bus, train via Nuevo Laredo
- Take the bus from Terminal Central de Autobuses del Norte to Nuevo Laredobus
- Take the bus from Nuevo Laredo to San Antoniobus
- Take the train from San Antonio Station to St. Louistrain
47h 40m$425–943
Benito Juárez International Airport (MEX) to Lambert–St. Louis International Airport (STL) flights
Comparing Your Travel Options
The cheapest way to get from Mexico City to St. Louis is to fly and drive which costs $130 - $550 and takes 11h 16m.
The fastest way to get from Mexico City to St. Louis is to fly which takes 8h 3m and costs $140 - $750.
No, there is no direct bus from Mexico City to St. Louis station. However, there are services departing from Terminal Central de Autobuses del Norte and arriving at St Louis Bus Station via Downtown Dallas / Deep Ellum and Oklahoma City Bus Station. The journey, including transfers, takes approximately 42h 34m.
The distance between Mexico City and St. Louis is 1458 miles. The road distance is 1717.1 miles.
The best way to get from Mexico City to St. Louis without a car is to bus which takes 42h 34m and costs $290 - $410.
It takes approximately 8h 3m to get from Mexico City to St. Louis, including transfers.
Mexico City to St. Louis bus services, operated by Omnibus Express (OMEX VIP), depart from Terminal Central de Autobuses del Norte station.
The best way to get from Mexico City to St. Louis is to fly which takes 8h 3m and costs $140 - $750. Alternatively, you can bus, which costs $290 - $410 and takes 42h 34m.
Mexico City to St. Louis bus services, operated by Omnibus Express (OMEX VIP), arrive at Dallas station.
St. Louis is 1h ahead of Mexico City. It is currently 7:17 PM in Mexico City and 8:17 PM in St. Louis.
What companies run services between Mexico City, Mexico and St. Louis, MO, USA?
American Airlines, Delta, and three other airlines fly from Benito Juárez International Airport (MEX) to Lambert–St. Louis International Airport (STL) every 2 hours. Alternatively, you can take a bus from Terminal Central de Autobuses del Norte to St Louis Bus Station via Dallas, Downtown Dallas / Deep Ellum, and Oklahoma City Bus Station in around 42h 34m.
- Website
- united.com
Flights from Benito Juárez International Airport to Lambert–St. Louis International Airport via Houston
- Ave. Duration
- 7h 12m
- When
- Every day
- Estimated price
- $140–700
Flights from Benito Juárez International Airport to Lambert–St. Louis International Airport via Chicago O'Hare
- Ave. Duration
- 7h 48m
- When
- Monday, Wednesday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $180–800
Flights from Benito Juárez International Airport to Barkley Regional Airport via Houston
- Ave. Duration
- 8h 52m
- When
- Every day
- Estimated price
- $100–500
Flights from Benito Juárez International Airport to Barkley Regional Airport via Chicago O'Hare
- Ave. Duration
- 6h 47m
- When
- Every day
- Estimated price
- $190–1,100
Flights from General Francisco Mujica International Airport to Lambert–St. Louis International Airport via Houston
- Ave. Duration
- 6h 20m
- When
- Every day
- Estimated price
- $230–1,100
Flights from Hermanos Serdán International Airport to Lambert–St. Louis International Airport via Houston
- Ave. Duration
- 7h 58m
- When
- Every day
- Estimated price
- $190–900
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from San Marcos Amtrak to St. Louis
- Ave. Duration
- 23h 8m
- Frequency
- Once daily
- Estimated price
- $240–600
- Website
- Amtrak
Train from San Marcos Amtrak to St. Louis
- Ave. Duration
- 23h 8m
- Frequency
- Once daily
- Estimated price
- $240–600
- Website
- Amtrak
Train from San Antonio Station to St. Louis
- Ave. Duration
- 24h 42m
- Frequency
- Once daily
- Estimated price
- $250–650
- Website
- Amtrak
- Phone
- +1 800 923 1799
- [email protected]
- Website
- Omnibus Express (OMEX VIP)
Bus from Terminal Central de Autobuses del Norte to Dallas
- Ave. Duration
- 26h 54m
- Frequency
- Once daily
- Estimated price
- $180–230
- Schedules at
- Omnibus Express (OMEX VIP)
Bus from Terminal Central de Autobuses del Norte to San Marcos
- Ave. Duration
- 21h 16m
- Frequency
- Once daily
- Estimated price
- $140–230
- Schedules at
- Omnibus Express (OMEX VIP)
Bus from Toluca to San Marcos
- Ave. Duration
- 19h 11m
- Frequency
- Once daily
- Estimated price
- $140–180
- Schedules at
- Omnibus Express (OMEX VIP)
- Ave. Duration
- 42 min
- Estimated price
- $80–95
Want to know more about travelling around United States
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Booking & Getting There
Yes, the driving distance between Mexico City to St. Louis is 1717 miles. It takes approximately 31h 9m to drive from Mexico City to St. Louis.
Book your Mexico City to St. Louis bus tickets online with Omio.
There are 566+ hotels available in St. Louis.









