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How to get fromMexico to Panama Cityby plane, bus, or car

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There are 8 ways to get from Mexico to Panama City by plane, bus, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Benito Juárez International Airport

    best
    1. Fly from Benito Juárez International Airport (MEX) to Tocumen International Airport (PTY)plane plane MEX - PTY
    6h 37m
    $348–740

  2. Fly from Felipe Ángeles International Airport

    cheapest
    1. Fly from Felipe Ángeles International Airport (NLU) to Tocumen International Airport (PTY)plane plane NLU - PTY
    11h 1m
    $141–493

  3. Bus

    1. Take the bus from México City to Tapachulabus bus
    2. Take the bus from Tapachula to Guatemana Aguilar Batresbus bus
    3. Take the bus from Guatemala Aguilar Batres to Terminal San Carlos - Ticabusbus bus
    4. Take the bus from Terminal Tica Bus San Salvador to Terminal Tica Bus San Josébus bus
    5. Take the bus from Terminal Tica Bus San José to Terminal Tica Bus Panamábus bus
    2d 20h
    $201–290

  4. Drive  3,152.7 km

    1. Drive from Mexico City to Panama Citycar car 3,152.7 km
    44h 56m
    $429–619

  5. Fly from Miguel Hidalgo Y Costilla Guadalajara International Airport

    1. Fly from Miguel Hidalgo Y Costilla Guadalajara International Airport (GDL) to Tocumen International Airport (PTY)plane plane GDL - PTY
    7h 59m
    $146–496

  6. Fly from Del Bajío International Airport

    1. Fly from Del Bajío International Airport (BJX) to Tocumen International Airport (PTY)plane plane BJX - PTY
    9h 47m
    $640–2,142

  7. Fly from Hermanos Serdán International Airport

    1. Fly from Hermanos Serdán International Airport (PBC) to Tocumen International Airport (PTY)plane plane PBC - PTY
    11h 1m
    $200–794

  8. Fly from Querétaro Intercontinental Airport

    1. Fly from Querétaro Intercontinental Airport (QRO) to Tocumen International Airport (PTY)plane plane QRO - PTY
    11h 3m
    $171–646

Benito Juárez International Airport (MEX) to Tocumen International Airport (PTY) flights

Calendar61Weekly Planes
Duration4h 18mAverage Duration
Ticket$106Cheapest Price
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Comparing Your Travel Options

Map of how to get from Mexico to Panama City.ExpandLaunch map view
  • Distance: 2,441.3 km
  • Duration: 6h 37m

What companies run services between Mexico and Panama City, Panama?

Aeroméxico, Copa Airlines, and Avianca - Aerovías del Continente Americano S.A. fly from Benito Juárez International Airport (MEX) to Tocumen International Airport (PTY) every 3 hours. Alternatively, you can take a bus from México City to Terminal Tica Bus Panamá via Tapachula, Guatemala Aguilar Batres, Terminal San Carlos - Ticabus, Terminal Tica Bus San Salvador, and Terminal Tica Bus San José in around 2d 20h.

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