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How to get fromMichigan City to Knoxvilleby train, plane, bus, or car

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There are 10 ways to get from Michigan City to Knoxville by train, plane, bus, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train to Chicago O'Hare International Airport, fly to Mcghee Tyson Airport

    best
    1. Take the train from 11th Street to Van Buren St.train train
    2. Fly from Chicago O'Hare International Airport (ORD) to Mcghee Tyson Airport (TYS)plane plane ORD - TYS
    5h 21m
    $167–686

  2. Drive 495.9 mi

    cheapest
    1. Drive from Michigan City to Knoxvillecar car 495.9 mi
    9h 7m
    $91–131

  3. Train, bus via Farragut

    1. Take the train from 11th Street to Van Buren St.train train Ssl
    2. Take the train from Chicago Union Station to Ny Moynihan Train Hall At Penn Stationtrain train
    3. Take the bus from New York to Knoxvillebus bus Nyc
    36h 21m
    $506–917

  4. Train, bus

    1. Take the train from 11th Street to Millennium Stationtrain train Ssl
    2. Take the bus from Chicago Bus Station to New York City Chinatownbus bus
    3. Take the bus from New York, NY to Knoxville, TNbus bus Ny
    40h 28m
    $272–409

  5. Train to South Bend, fly to Mcghee Tyson Airport

    1. Take the train from 11th Street to South Bend Airporttrain train
    2. Fly from South Bend (SBN) to Mcghee Tyson Airport (TYS)plane plane SBN - TYS
    5h 59m
    $213–928

  6. Train to Chicago Midway International Airport, fly to Mcghee Tyson Airport

    1. Take the train from 11th Street to Van Buren St.train train
    2. Fly from Chicago Midway International Airport (MDW) to Mcghee Tyson Airport (TYS)plane plane MDW - TYS
    4h 53m
    $197–886

  7. Train to Chicago O'Hare International Airport, fly to Chattanooga Metropolitan Airport, drive

    1. Take the train from 11th Street to Van Buren St.train train
    2. Fly from Chicago O'Hare International Airport (ORD) to Chattanooga Metropolitan Airport (CHA)plane plane ORD - CHA
    3. Drive from Chattanooga Metropolitan Airport (CHA) to Knoxvillecar car
    6h 50m
    $140–694

  8. Train to Chicago O'Hare International Airport, fly to Asheville Regional Airport, drive

    1. Take the train from 11th Street to Van Buren St.train train
    2. Fly from Chicago O'Hare International Airport (ORD) to Asheville Regional Airport (AVL)plane plane ORD - AVL
    3. Drive from Asheville-Airport-AVL to Knoxvillecar car
    7h 23m
    $94–391

  9. Train to Chicago Midway International Airport, fly to Nashville, drive

    1. Take the train from 11th Street to Van Buren St.train train
    2. Fly from Chicago Midway International Airport (MDW) to Nashville (BNA)plane plane MDW - BNA
    3. Drive from Nashville-Airport-BNA to Knoxvillecar car
    7h 21m
    $117–506

  10. Train, bus via Ossining

    1. Take the train from 11th Street to Van Buren St.train train Ssl
    2. Take the train from Chicago Union Station to Croton-Harmon Amtrak Stationtrain train
    3. Take the train from Croton-Harmon to 125th Street - Harlemtrain train
    4. Take the bus from New York, NY to Knoxville, TNbus bus Ny
    36h 58m
    $461–844

Chicago O'Hare International Airport (ORD) to Mcghee Tyson Airport (TYS) flights

Calendar75Weekly Planes
Duration2h 58mAverage Duration
Ticket$108Cheapest Price
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Questions & Answers

Map of how to get from Michigan City to Knoxville.ExpandLaunch map view
  • Distance: 561 mi
  • Duration: 5h 21m

What companies run services between Michigan City, IN, USA and Knoxville, TN, USA?

There is no direct connection from Michigan City to Knoxville. However, you can take the train to Van Buren St., walk to Jackson-Blue, take the subway to O'Hare, walk to Chicago O'Hare International Airport (ORD) airport, fly to Mcghee Tyson Airport (TYS), then take the taxi to Knoxville. Alternatively, you can take a train from 11th Street to Knoxville via Van Buren St., Michigan & Van Buren, Clinton & Jackson, Chicago Union Station, Ny Moynihan Train Hall At Penn Station, 34 St-Herald Sq, East Broadway, New York, and Knoxville in around 36h 21m.

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