Rome2Rio

How to get fromMichigan City to Mayo Clinicby train, plane, bus, or car

Find Transport to Mayo Clinic

See all options

There are 9 ways to get from Michigan City to Mayo Clinic by train, plane, bus, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train to Chicago O'Hare International Airport, fly to Rochester

    best
    1. Take the train from 11th Street to Van Buren St.train train
    2. Fly from Chicago O'Hare International Airport (ORD) to Rochester (RST)plane plane ORD - RST
    5h 58m
    $53–346

  2. Train, bus via Milwaukee

    1. Take the train from 11th Street to Van Buren St.train train Ssl
    2. Take the train from Chicago Union Station to Milwaukeetrain train
    3. Take the bus from Milwaukee to Rochesterbus bus
    10h 53m
    $110–174

  3. Train, bus

    1. Take the train from 11th Street to Van Buren St.train train Ssl
    2. Take the train from Chicago Union Station to St. Paul-Minneapolistrain train
    3. Take the bus from St. Paul to Rochester, MNbus bus
    12h 53m
    $170–326

  4. Drive 403.1 mi

    1. Drive from Michigan City to Mayo Cliniccar car 403.1 mi
    6h 52m
    $74–107

  5. Train to South Bend, fly to Minneapolis–Saint Paul International Airport, bus

    1. Take the train from 11th Street to South Bend Airporttrain train
    2. Fly from South Bend (SBN) to Minneapolis–Saint Paul International Airport (MSP)plane plane SBN - MSP
    3. Take the bus from Minneapolis / St Paul Airport to Groome Transportation Office - Rochesterbus bus
    6h 24m
    $135–530

  6. Train to Chicago O'Hare International Airport, fly to Minneapolis–Saint Paul International Airport, bus

    1. Take the train from 11th Street to Van Buren St.train train
    2. Fly from Chicago O'Hare International Airport (ORD) to Minneapolis–Saint Paul International Airport (MSP)plane plane ORD - MSP
    3. Take the bus from Minneapolis / St Paul Airport to Groome Transportation Office - Rochesterbus bus
    7h 41m
    $284–518

  7. Train to Chicago Midway International Airport, fly to Minneapolis–Saint Paul International Airport, bus

    1. Take the train from 11th Street to Van Buren St.train train
    2. Fly from Chicago Midway International Airport (MDW) to Minneapolis–Saint Paul International Airport (MSP)plane plane MDW - MSP
    3. Take the bus from Minneapolis / St Paul Airport to Groome Transportation Office - Rochesterbus bus
    7h 30m
    $139–548

  8. Train, bus via Gary

    1. Take the train from 11th Street to Garytrain train Ssl
    2. Take the bus from Gary Bus Station to Chicago Bus Stationbus bus
    3. Take the bus from Chicago Bus Station to Milwaukee Intermodal Stationbus bus
    4. Take the bus from Milwaukee to Rochesterbus bus
    11h 36m
    $94–143

  9. Train, bus #2

    1. Take the train from 11th Street to Van Buren St.train train Ssl
    2. Take the bus from W Jackson Blvd, after S Clinton St to 250 N. Lake St - Madison UW Campusbus bus
    3. Take the bus from Madison to Rochesterbus bus
    11h 42m
    $88–144

Chicago O'Hare International Airport (ORD) to Rochester (RST) flights

Calendar35Weekly Planes
Duration1h 53mAverage Duration
Ticket$44Cheapest Price
See schedules

Questions & Answers

Map of how to get from Michigan City to Mayo Clinic.ExpandLaunch map view
  • Distance: 349.8 mi
  • Duration: 5h 58m

What companies run services between Michigan City, IN, USA and Mayo Clinic, MN, USA?

There is no direct connection from Michigan City to Mayo Clinic. However, you can take the train to Van Buren St., walk to Jackson-Blue, take the subway to O'Hare, walk to Chicago O'Hare International Airport (ORD) airport, fly to Rochester (RST), walk to Rochester - Airport, take the shuttle to Rochester, then walk to Mayo Clinic. Alternatively, you can take a train from 11th Street to Mayo Clinic via Van Buren St., Michigan & Van Buren, Clinton & Jackson, Chicago Union Station, Milwaukee, Milwaukee, and Rochester in around 10h 53m.

Airlines
Train operators
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound