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How to get fromMichigan to Florenceby plane, bus (Greyhound), bus, train, or car

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There are 6 ways to get from Michigan to Florence by plane, bus (Greyhound), bus, train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Florence Regional Airport

    best
    1. Fly from Detroit (DTW) to Florence Regional Airport (FLO)plane plane DTW - FLO
    5h 47m
    $102–515

  2. Bus via Columbus

    cheapest
    1. Take the bus from Detroit to Columbusbus bus
    2. Take the bus from Columbus to Charlottebus bus
    3. Take the bus from Charlotte Bus Station to Camdenbus bus
    4. Take the bus from Camden to Florence Bus Stationbus bus
    20h 10m
    $84–192

  3. Bus, train

    1. Take the bus from Detroit Bus Station to Toledo Bus Stopbus bus
    2. Take the train from Toledo to Petersburg Amtrak Stationtrain train
    3. Take the train from Petersburg Amtrak Station to Florence Stationtrain train
    25h 5m
    $256–697

  4. Drive  710.2 mi

    1. Drive from Detroit to Florencecar car 710.2 mi
    13h 18m
    $130–188

  5. Fly to Myrtle Beach, bus

    1. Fly from Detroit (DTW) to Myrtle Beach (MYR)plane plane DTW - MYR
    2. Take the bus from Myrtle Beach Bus Station to Florence Bus Stationbus bus
    6h 20m
    $109–503

  6. Bus (Greyhound)

    1. Take the bus from Detroit Bus Station to Charlotte Bus Stationbus bus
    2. Take the bus from Charlotte Bus Station to Camdenbus bus
    3. Take the bus from Camden to Florence Bus Stationbus bus
    20h 25m
    $131–206

Michigan to Florence by bus

Calendar7Weekly Buses
Duration20h 10mAverage Duration
Ticket$84Cheapest Price
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Comparing Your Travel Options

Map of how to get from Michigan to Florence.ExpandLaunch map view
  • Distance: 605.2 mi
  • Duration: 5h 47m

What companies run services between Michigan, USA and Florence, SC, USA?

American Airlines and Delta fly from Detroit (DTW) to Florence Regional Airport (FLO) 3 times a day. Alternatively, you can take a bus from Detroit to Florence Bus Station via Columbus, Charlotte Bus Station, and Camden in around 20h 10m.

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Want to know more about travelling around United States

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Need to know: Greyhound

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