There are 5 ways to get from Michigan to Florence by plane, bus (Greyhound), bus, train, or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly
best- Fly from Detroit (DTW) to Florence Regional Airport (FLO)plane DTW - FLO
5h 37m$97–515Bus via Columbus
cheapest- Take the bus from Detroit Bus Station to N Wilson Rd & Ferrell Pl - Columbusbus
- Take the bus from Columbus to Charlottebus
- Take the bus from Charlotte Bus Station to Camdenbus
- Take the bus from Camden to Florence Bus Stationbus
19h 40m$82–188Bus, train
- Take the bus from Detroit Bus Station to Toledo Bus Stopbus
- Take the train from Toledo to Petersburg Amtrak Stationtrain
- Take the train from Petersburg Amtrak Station to Florence Stationtrain
25h 5m$241–587Drive 710.2 mi
- Drive from Detroit to Florencecar 710.2 mi
13h 18m$130–188Bus (Greyhound)
- Take the bus from Detroit Bus Station to Charlotte Bus Stationbus
- Take the bus from Charlotte Bus Station to Camdenbus
- Take the bus from Camden to Florence Bus Stationbus
20h 25m$126–201
Michigan to Florence by bus
Comparing Your Travel Options
The cheapest way to get from Michigan to Florence is to bus via Columbus which costs $80 - $190 and takes 19h 40m.
The fastest way to get from Michigan to Florence is to fly which takes 5h 37m and costs $95 - $550.
No, there is no direct bus from Michigan station to Florence station. However, there are services departing from Detroit Bus Station and arriving at Florence Bus Station via Columbus, Charlotte Bus Station and Camden. The journey, including transfers, takes approximately 19h 40m.
The distance between Michigan and Florence is 609 miles. The road distance is 714.3 miles.
The best way to get from Michigan to Florence without a car is to bus via Columbus which takes 19h 40m and costs $80 - $190.
It takes approximately 5h 37m to get from Michigan to Florence, including transfers.
Michigan to Florence bus services, operated by Greyhound USA, depart from Detroit Bus Station.
The best way to get from Michigan to Florence is to fly which takes 5h 37m and costs $95 - $550. Alternatively, you can bus via Columbus, which costs $80 - $190 and takes 19h 40m.
Michigan to Florence bus services, operated by Greyhound USA, arrive at Charlotte Bus Station.
Yes, the driving distance between Michigan to Florence is 714 miles. It takes approximately 13h 18m to drive from Michigan to Florence.
What companies run services between Michigan, USA and Florence, SC, USA?
American Airlines and Delta fly from Detroit (DTW) to Florence Regional Airport (FLO) 4 times a day. Alternatively, you can take a bus from Detroit Bus Station to Florence Bus Station via Columbus, Charlotte Bus Station, and Camden in around 19h 40m.
- Website
- aa.com
Flights from Detroit to Florence Regional Airport via Charlotte
- Ave. Duration
- 4h 57m
- When
- Every day
- Estimated price
- $85–500
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Toledo to Petersburg Amtrak Station
- Ave. Duration
- 16h 52m
- Frequency
- Once daily
- Estimated price
- $170–390
- Website
- Amtrak
Train from Petersburg Amtrak Station to Florence Station
- Ave. Duration
- 5h 8m
- Frequency
- Twice daily
- Estimated price
- $65–160
- Website
- Amtrak
- Phone
- +1 888-378-3823
- [email protected]
- Website
- Barons Bus
Bus from Detroit Bus Station to N Wilson Rd & Ferrell Pl - Columbus
- Ave. Duration
- 3h 45m
- Frequency
- Twice daily
- Estimated price
- $18–60
- Website
- Barons Bus
Bus from Columbus to Charlotte
- Ave. Duration
- 10h 20m
- Frequency
- Once daily
- Estimated price
- $45–100
- Website
- Barons Bus
Bus from Detroit Bus Station to Toledo Bus Stop
- Ave. Duration
- 1h
- Frequency
- 5 times a day
- Estimated price
- $5–40
- Website
- Barons Bus
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
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Booking & Getting There
Book your Michigan to Florence bus tickets online with Omio and FlixBus.
There are 46+ hotels available in Florence.







