There are 7 ways to get from Michigan to Knoxville by plane, bus (Greyhound, Flixbus), bus, train, car, or bus (Greyhound)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly from Capital Region International Airport
best- Fly from Capital Region International Airport (LAN) to Mcghee Tyson Airport (TYS)plane LAN - TYS
3h 51m$234–1,042Drive 507.9 mi
cheapest- Drive from Detroit to Knoxvillecar 507.9 mi
8h 34m$93–134Bus via Toledo
- Take the bus from Detroit Bus Station to Toledo Bus Stopbus
- Take the bus from Toledo Bus Stop to New York Midtownbus
- Take the bus from New York to Knoxvillebus Nyc
27h 46m$279–440Bus, train via Farragut
- Take the bus from Detroit Bus Station to Toledo Bus Stopbus
- Take the train from Toledo to Ny Moynihan Train Hall At Penn Stationtrain
- Take the bus from New York to Knoxvillebus Nyc
30h 49m$389–740Fly from Detroit
- Fly from Detroit (DTW) to Mcghee Tyson Airport (TYS)plane DTW - TYS
3h 29m$197–972Bus
- Take the bus from Detroit Bus Station to Port Authority Bus Terminalbus Greyhound US0420
- Take the bus from New York to Knoxvillebus Nyc
30h 52m$286–446Bus, train
- Take the bus from Detroit Bus Station to Toledo Bus Stopbus
- Take the train from Toledo to Ny Moynihan Train Hall At Penn Stationtrain
- Take the bus from New York, NY to Knoxville, TNbus Ny
30h 53m$344–650
Capital Region International Airport (LAN) to Mcghee Tyson Airport (TYS) flights
Questions & Answers
The cheapest way to get from Michigan to Knoxville is to drive which costs $90 - $140 and takes 8h 34m.
The fastest way to get from Michigan to Knoxville is to fly which takes 3h 29m and costs $190 - $1,000.
No, there is no direct bus from Michigan station to Knoxville. However, there are services departing from Detroit Bus Station and arriving at Knoxville via Toledo Bus Stop and New York. The journey, including transfers, takes approximately 27h 46m.
The distance between Michigan and Knoxville is 503 miles. The road distance is 510.8 miles.
The best way to get from Michigan to Knoxville without a car is to bus via Toledo which takes 27h 46m and costs $270 - $440.
It takes approximately 3h 51m to get from Michigan to Knoxville, including transfers.
Michigan to Knoxville bus services, operated by Greyhound USA, depart from Detroit Bus Station.
The best way to get from Michigan to Knoxville is to fly which takes 3h 51m and costs $230 - $1,100. Alternatively, you can bus via Toledo, which costs $270 - $440 and takes 27h 46m.
Michigan to Knoxville bus services, operated by Greyhound USA, arrive at Toledo Bus Stop station.
Yes, the driving distance between Michigan to Knoxville is 511 miles. It takes approximately 8h 34m to drive from Michigan to Knoxville.
What companies run services between Michigan, USA and Knoxville, TN, USA?
Delta, American Airlines, and United Airlines fly from Capital Region International Airport (LAN) to Mcghee Tyson Airport (TYS) every 4 hours. Alternatively, you can take a bus from Detroit Bus Station to Knoxville via Toledo Bus Stop, New York Midtown, 23 St, East Broadway, New York, and Knoxville in around 27h 46m.
- Website
- delta.com
Flights from Capital Region International Airport to Mcghee Tyson Airport via Detroit
- Ave. Duration
- 4h 29m
- When
- Every day
- Estimated price
- $160–950
Flights from Detroit to Mcghee Tyson Airport
- Ave. Duration
- 1h 36m
- When
- Every day
- Estimated price
- $140–900
Flights from Detroit to Mcghee Tyson Airport via Atlanta
- Ave. Duration
- 3h 58m
- When
- Every day
- Estimated price
- $200–1,100
- Website
- aa.com
Flights from Capital Region International Airport to Mcghee Tyson Airport via Reagan Washington
- Ave. Duration
- 4h 42m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $240–1,200
Flights from Capital Region International Airport to Mcghee Tyson Airport via Chicago O'Hare
- Ave. Duration
- 5h 43m
- When
- Every day
- Estimated price
- $190–1,100
Flights from Detroit to Mcghee Tyson Airport via Charlotte
- Ave. Duration
- 4h 2m
- When
- Thursday, Sunday, Monday, and Tuesday
- Estimated price
- $190–1,000
- Website
- united.com
Flights from Capital Region International Airport to Mcghee Tyson Airport via Chicago O'Hare
- Ave. Duration
- 6h 18m
- When
- Every day
- Estimated price
- $190–1,100
- Website
- southwest.com
Flights from Detroit to Mcghee Tyson Airport via Baltimore
- Ave. Duration
- 4h 5m
- When
- Monday, Thursday, and Friday
- Estimated price
- $220–1,100
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Toledo to Ny Moynihan Train Hall At Penn Station
- Ave. Duration
- 15h 11m
- Frequency
- Once daily
- Estimated price
- $200–450
- Website
- Amtrak
Train from Toledo to Ny Moynihan Train Hall At Penn Station
- Ave. Duration
- 15h 11m
- Frequency
- Once daily
- Estimated price
- $200–450
- Website
- Amtrak
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Detroit Bus Station to Toledo Bus Stop
- Ave. Duration
- 1h 5m
- Frequency
- Every 4 hours
- Estimated price
- $8–16
- Website
- Greyhound
Bus from Detroit Bus Station to Toledo Bus Stop
- Ave. Duration
- 1h 5m
- Frequency
- Every 4 hours
- Estimated price
- $8–16
- Website
- Greyhound
Bus from Detroit Bus Station to Port Authority Bus Terminal
- Ave. Duration
- 17h 15m
- Frequency
- Once daily
- Estimated price
- $100–200
- Website
- Greyhound
Bus from Detroit Bus Station to Toledo Bus Stop
- Ave. Duration
- 1h 5m
- Frequency
- Every 4 hours
- Estimated price
- $8–16
- Website
- Greyhound
- Phone
- +1 888-378-3823
- [email protected]
- Website
- Barons Bus
Bus from Detroit Bus Station to Toledo Bus Stop
- Ave. Duration
- 1h
- Frequency
- 3 times a day
- Estimated price
- $5–40
- Website
- Barons Bus
Bus from Detroit Bus Station to Toledo Bus Stop
- Ave. Duration
- 1h
- Frequency
- 3 times a day
- Estimated price
- $5–40
- Website
- Barons Bus
Bus from Detroit Bus Station to Toledo Bus Stop
- Ave. Duration
- 1h
- Frequency
- 3 times a day
- Estimated price
- $5–40
- Website
- Barons Bus
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Toledo Bus Stop to New York Midtown
- Ave. Duration
- 12h 5m
- Frequency
- 6 times a week
- Estimated price
- $90–150
- Schedules at
- Flixbus USA
- Phone
- +1 646-630-7186
- [email protected]
- Website
- Wanda Coach
Bus from New York to Knoxville
- Ave. Duration
- 11h 45m
- Frequency
- Once daily
- Estimated price
- $95–140
- Website
- Wanda Coach
- Book at
- GotoBus.com
- Adult One Way
- $95–140
Bus from New York to Knoxville
- Ave. Duration
- 11h 45m
- Frequency
- Once daily
- Estimated price
- $95–140
- Website
- Wanda Coach
- Book at
- GotoBus.com
- Adult One Way
- $95–140
Bus from New York to Knoxville
- Ave. Duration
- 11h 45m
- Frequency
- Once daily
- Estimated price
- $95–140
- Website
- Wanda Coach
- Book at
- GotoBus.com
- Adult One Way
- $95–140
- Phone
- +1 615-939-8887
- [email protected]
- Website
- New York to Tennessee Bus
Bus from New York, NY to Knoxville, TN
- Ave. Duration
- 12h
- Frequency
- Once daily
- Estimated price
- $95–110
- Website
- New York to Tennessee Bus
- Adult One-way
- $95–110
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Need to know: Greyhound
Read the travel guide
Why you should take the train in the US
Read the travel guide
More Questions & Answers
There are 316+ hotels available in Knoxville.










