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How to get fromMichigan to Louisvilleby bus (Greyhound), car, plane, or bus (Amtrak)

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There are 7 ways to get from Michigan to Louisville by bus (Greyhound), car, plane, or bus (Amtrak)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus

    best
    1. Take the bus from Detroit Bus Station to Cincinnati Bus Stationbus bus Greyhound US0135 / ...
    2. Take the bus from Greyhound Station Cincinnati to Louisville, KY Bus Stationbus bus Cleveland
    7h 50m
    $34–109

  2. Drive 356 mi

    1. Drive from Detroit to Louisvillecar car 356 mi
    6h 5m
    $65–94

  3. Fly Capital Region International Airport to Louisville International Airport

    1. Fly from Capital Region International Airport (LAN) to Louisville International Airport (SDF)plane plane LAN - SDF
    5h 5m
    $110–575

  4. Bus via Indianapolis

    1. Take the bus from Detroit, MI to Indianapolis, INbus bus Detroit
    2. Take the bus from Indianapolis Union Station to Louisville, KYbus bus Chicago
    8h 45m
    $49–114

  5. Fly Detroit to Louisville International Airport

    1. Fly from Detroit (DTW) to Louisville International Airport (SDF)plane plane DTW - SDF
    4h 16m
    $78–485

  6. Fly Detroit to Blue Grass Airport, drive

    1. Fly from Detroit (DTW) to Blue Grass Airport (LEX)plane plane DTW - LEX
    2. Drive from Lexington-Airport-LEX to Louisvillecar car
    4h 21m
    $125–771

  7. Fly Gerald R. Ford International Airport to Louisville International Airport

    1. Fly from Gerald R. Ford International Airport (GRR) to Louisville International Airport (SDF)plane plane GRR - SDF
    7h 6m
    $100–607

Michigan to Louisville by bus

Calendar14Weekly Buses
Duration7h 50mAverage Duration
Ticket$34Cheapest Price
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Questions & Answers

Map of how to get from Michigan to Louisville.ExpandLaunch map view
  • Distance: 358.6 mi
  • Duration: 7h 50m

What companies run services between Michigan, USA and Louisville, KY, USA?

You can take a bus from Detroit Bus Station to Louisville, KY Bus Station via Cincinnati Bus Station and Greyhound Station Cincinnati in around 7h 50m. Alternatively, American Airlines, Delta, and three other airlines fly from Capital Region International Airport (LAN) to Louisville International Airport (SDF) every 4 hours.

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