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How to get fromMichigan to Mayo Clinicby plane, bus (Flixbus), car, bus, train, or bus (Amtrak)

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There are 9 ways to get from Michigan to Mayo Clinic by plane, bus (Flixbus), car, bus, train, or bus (Amtrak)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Capital Region International Airport to Rochester

    best
    1. Fly from Capital Region International Airport (LAN) to Rochester (RST)plane plane LAN - RST
    5h 28m
    $90–482

  2. Fly Gerald R. Ford International Airport to Rochester

    cheapest
    1. Fly from Gerald R. Ford International Airport (GRR) to Rochester (RST)plane plane GRR - RST
    7h 52m
    $70–444

  3. Bus

    1. Take the bus from Detroit Bus Station to Milwaukee Intermodal Stationbus bus FlixBus 2550
    2. Take the bus from Milwaukee to Rochesterbus bus Jefferson 966 / ...
    14h 28m
    $129–196

  4. Drive 627.5 mi

    1. Drive from Detroit to Mayo Cliniccar car 627.5 mi
    10h 23m
    $115–166

  5. Fly Detroit to Rochester

    1. Fly from Detroit (DTW) to Rochester (RST)plane plane DTW - RST
    6h 31m
    $78–462

  6. Fly Detroit to Minneapolis–Saint Paul International Airport, bus

    1. Fly from Detroit (DTW) to Minneapolis–Saint Paul International Airport (MSP)plane plane DTW - MSP
    2. Take the bus from Minneapolis / St Paul Airport to Groome Transportation Office - Rochesterbus bus
    6h 22m
    $524–1,254

  7. Fly Gerald R. Ford International Airport to Minneapolis–Saint Paul International Airport, bus

    1. Fly from Gerald R. Ford International Airport (GRR) to Minneapolis–Saint Paul International Airport (MSP)plane plane GRR - MSP
    2. Take the bus from Minneapolis / St Paul Airport to Groome Transportation Office - Rochesterbus bus
    7h 3m
    $141–556

  8. Train, bus

    1. Take the train from Detroit to Chicago Union Stationtrain train
    2. Take the bus from W Jackson Blvd, after S Clinton St to 250 N. Lake St - Madison UW Campusbus bus
    3. Take the bus from Madison to Rochesterbus bus
    16h 31m
    $167–314

  9. Bus via Chicago

    1. Take the bus from Detroit to Chicago Union Stationbus bus
    2. Take the bus from W Jackson Blvd, after S Clinton St to 250 N. Lake St - Madison UW Campusbus bus
    3. Take the bus from Madison to Rochesterbus bus
    16h 49m
    $172–272

Capital Region International Airport (LAN) to Rochester (RST) flights

Calendar21Weekly Planes
Duration5h 59mAverage Duration
Ticket$74Cheapest Price
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Questions & Answers

Map of how to get from Michigan to Mayo Clinic.ExpandLaunch map view
  • Distance: 418.3 mi
  • Duration: 5h 28m

What companies run services between Michigan, USA and Mayo Clinic, MN, USA?

American Airlines flies from Capital Region International Airport (LAN) to Rochester (RST) 3 times a day. Alternatively, you can take a bus from Detroit Bus Station to Mayo Clinic via Milwaukee Intermodal Station, Milwaukee, and Rochester in around 14h 28m.

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