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How to get fromMiddleburg to Fort Myersby bus (Flixbus), taxi, train, bus, car, plane, or bus (Amtrak)

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There are 9 ways to get from Middleburg to Fort Myers by bus (Flixbus), taxi, train, bus, car, plane, or bus (Amtrak)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus

    best
    1. Take the bus from Keystone Heights Senior Center to Gainesville RTS Downtown Stationbus bus 903
    2. Take the bus from Gainesville to Tampa Bus Stationbus bus
    3. Take the bus from Tampa Bus Station to Fort Myers Bus Stopbus bus
    10h
    $64–95

  2. Drive 265.9 mi

    cheapest
    1. Drive from Middleburg to Fort Myerscar car 265.9 mi
    5h 31m
    $49–71

  3. Taxi, train, bus

    1. Take the taxi from Middleburg to Jacksonvilletaxi taxi
    2. Take the train from Jacksonville to Tampatrain train
    3. Take the bus from Tampa Bus Station to Fort Myers Bus Stopbus bus
    10h 31m
    $152–267

  4. Taxi to Jacksonville, fly to Ft. Myers

    1. Take the taxi from Middleburg to Jacksonville-Airport-JAXtaxi taxi
    2. Fly from Jacksonville (JAX) to Ft. Myers (RSW)plane plane JAX - RSW
    6h 34m
    $396–927

  5. Bus via Orlando (Flixbus)

    1. Take the bus from Jacksonville to Orlando Bus Stationbus bus FlixBus 2433 / ...
    2. Take the bus from Orlando Bus Station to Fort Myers Bus Stopbus bus FlixBus 2421
    10h 43m
    $86–131

  6. Bus #2

    1. Take the bus from Jacksonville to Wildwood Amtrak Stationbus bus Amtrak Thruway Connecting Service
    2. Take the bus from Wildwood to Fort Myersbus bus Houston
    11h 28m
    $137–193

  7. Taxi to Jacksonville, fly to Fort Lauderdale–Hollywood International Airport, bus

    1. Take the taxi from Middleburg to Jacksonville-Airport-JAXtaxi taxi
    2. Fly from Jacksonville (JAX) to Fort Lauderdale–Hollywood International Airport (FLL)plane plane JAX - FLL
    3. Take the bus from Fort Lauderdale International Airport to Fort Myers Bus Stopbus bus
    5h 35m
    $241–702

  8. Taxi to Jacksonville, fly to Miami International Airport, bus

    1. Take the taxi from Middleburg to Jacksonville-Airport-JAXtaxi taxi
    2. Fly from Jacksonville (JAX) to Miami International Airport (MIA)plane plane JAX - MIA
    3. Take the bus from Miami Airport Station to Fort Myers Bus Stopbus bus
    6h 41m
    $175–512

  9. Taxi to Gainesville Regional Airport, fly to Miami International Airport, bus

    1. Take the taxi from Middleburg to Gainesville-Airport-GNVtaxi taxi
    2. Fly from Gainesville Regional Airport (GNV) to Miami International Airport (MIA)plane plane GNV - MIA
    3. Take the bus from Miami Airport Station to Fort Myers Bus Stopbus bus
    6h 43m
    $217–537

Jacksonville (JAX) to Ft. Myers (RSW) flights

Calendar70Weekly Planes
Duration5h 28mAverage Duration
Ticket$99Cheapest Price
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Questions & Answers

Map of how to get from Middleburg to Fort Myers.ExpandLaunch map view
  • Distance: 321 mi
  • Duration: 10h

What companies run services between Middleburg, FL, USA and Fort Myers, FL, USA?

You can take a vehicle from Middleburg to Fort Myers Bus Stop via Penney Farms Commons Building, Keystone Heights Senior Center, Gainesville, and Tampa Bus Station in around 10h.

Airlines
Train operators
Bus operators
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