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How to get fromMiddlesboro to Birminghamby car, plane, or bus

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There are 5 ways to get from Middlesboro to Birmingham by car, plane, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Drive to Mcghee Tyson Airport, fly

    best
    1. Drive from Middlesboro to Mcghee Tyson Airport (TYS)car car
    2. Fly from Mcghee Tyson Airport (TYS) to Birmingham–Shuttlesworth International Airport (BHM)plane plane TYS - BHM
    4h 46m
    $138–788

  2. Drive 314.4 mi

    cheapest
    1. Drive from Middlesboro to Birminghamcar car 314.4 mi
    5h 38m
    $58–83

  3. Drive, bus via Nashville

    1. Drive from Middlesboro to Knoxvillecar car
    2. Take the bus from Knoxville to Nashvillebus bus Nyc
    3. Take the bus from Nashville Bus Station to Birmingham Intermodal Facilitybus bus
    9h 22m
    $86–140

  4. Drive to Tri-Cities Regional Tn/Va Airport, fly

    1. Drive from Middlesboro to Tri-Cities-Regional-Airport-TRIcar car
    2. Fly from Tri-Cities Regional Tn/Va Airport (TRI) to Birmingham–Shuttlesworth International Airport (BHM)plane plane TRI - BHM
    5h 14m
    $112–544

  5. Drive, bus (Greyhound)

    1. Drive from Middlesboro to Londoncar car
    2. Take the bus from London to Atlanta Bus Stationbus bus
    3. Take the bus from Atlanta Bus Station to Birmingham Intermodal Facilitybus bus
    10h 31m
    $76–149

Mcghee Tyson Airport (TYS) to Birmingham–Shuttlesworth International Airport (BHM) flights

Calendar89Weekly Planes
Duration4h 12mAverage Duration
Ticket$114Cheapest Price
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Questions & Answers

Map of how to get from Middlesboro to Birmingham.ExpandLaunch map view
  • Distance: 298 mi
  • Duration: 4h 46m

What companies run services between Middlesboro, KY, USA and Birmingham, AL, USA?

There is no direct connection from Middlesboro to Birmingham. However, you can drive to Mcghee Tyson Airport (TYS) airport, fly to Birmingham–Shuttlesworth International Airport (BHM), then take the taxi to Birmingham. Alternatively, you can take a vehicle from Middlesboro to Birmingham Intermodal Facility via Knoxville, Nashville, Charlotte Pike & Lellyett St Eb, Central 5Th Ave - Bay 1, Central 4Th Ave - Bay 13, Fulton Station Outbound, and Nashville Bus Station in around 9h 22m.

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