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How to get fromMiddlesboro to Columbiaby car, plane, or bus

Find Transport to Columbia

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There are 3 ways to get from Middlesboro to Columbia by car, plane, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Drive, fly

    best
    1. Drive from Middlesboro to Mcghee Tyson Airport (TYS)car car
    2. Fly from Mcghee Tyson Airport (TYS) to Columbia (CAE)plane plane TYS - CAE
    6h 11m
    $165–1,021

  2. Drive 283.3 mi

    cheapest
    1. Drive from Middlesboro to Columbiacar car 283.3 mi
    5h 19m
    $52–75

  3. Drive, bus

    1. Drive from Middlesboro to Londoncar car
    2. Take the bus from London to Atlanta Bus Stationbus bus
    3. Take the bus from Atlanta to Camdenbus bus
    4. Take the bus from Camden to Columbia, SCbus bus Nyc
    15h 22m
    $119–221

Mcghee Tyson Airport (TYS) to Columbia (CAE) flights

Calendar142Weekly Planes
Duration4h 25mAverage Duration
Ticket$158Cheapest Price
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Questions & Answers

Map of how to get from Middlesboro to Columbia.ExpandLaunch map view
  • Distance: 288.7 mi
  • Duration: 6h 11m

What companies run services between Middlesboro, KY, USA and Columbia, SC, USA?

There is no direct connection from Middlesboro to Columbia. However, you can drive to Mcghee Tyson Airport (TYS) airport, fly to Columbia (CAE), walk to Columbia Metropolitan Airport, then take the line 91 bus to Assembly Gervais North. Alternatively, you can take a vehicle from Middlesboro to Sumter Laurel South via London, Atlanta, Camden, Columbia, SC, and Broad Marley South in around 15h 22m.

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